butalbital, aspirin, and caffeine

Product NDC
62135-433
11-digit product format
621350433
Labeler code
62135
Product ID
62135-433_458c094e-5759-0b4a-e063-6394a90aa3f9
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
butalbital, aspirin, and caffeine
Dosage form
CAPSULE
Route
ORAL
Labeler
Chartwell RX, LLC
Application
ANDA086996
Marketing category
ANDA
Marketing start
1985-10-11
Substance
ASPIRIN; BUTALBITAL; CAFFEINE
Active strength
325; 50; 40 mg/1; mg/1; mg/1
Pharmacologic classes
Anti-Inflammatory Agents, Non-Steroidal [CS], Barbiturate [EPC], Barbiturates [CS], Central Nervous System Stimulant [EPC], Central Nervous System Stimulation [PE], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Methylxanthine [EPC], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC], Xanthines [CS]
DEA schedule
CIII
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A086996-002LANORINALASPIRIN; BUTALBITAL; CAFFEINE325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A086996-002AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-112680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-115bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-1179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-111e350fbaab3a…
2024-05-31 18:47 UTC2024-05A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-118072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-115c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-115d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-114b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-1174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-11bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-11782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-1187673890dc5c…
2021-03-12 10:30 UTC2021-03A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-115aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-118869cabd3fbd…
2020-11-12 02:37 UTC2020-11A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-11c0c555d07b60…
2019-12-14 00:12 UTC2019-12A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-113f01610625f2…
2019-09-15 20:21 UTC2019-09A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-11b00525d2431f…
2019-07-19 19:46 UTC2019-07A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAA1985-10-11ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-116a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-111c564ffb4f44…
2023-12-20 04:57 UTC2023-12A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-119b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-113f0d92c62455…
2023-05-13 08:27 UTC2023-05A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11053a50430f4f…
2023-01-26 05:58 UTC2023-01A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-113bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-113a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A086996-002LANORINAL325MG;50MG;40MGCAPSULE / ORALAARS1985-10-11cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A086996-002AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A086996-002AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A086996-002AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A086996-002AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A086996-002AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A086996-002AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A086996-002AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A086996-002AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A086996-002AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A086996-002AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A086996-002AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A086996-002AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A086996-002AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A086996-002AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A086996-002AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A086996-002AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A086996-002AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A086996-002AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A086996-002AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A086996-002AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A086996-002AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A086996-002AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A086996-002AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A086996-002AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A086996-002AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A086996-002AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A086996-002AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A086996-002AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A086996-002AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A086996-002AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A086996-002AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A086996-002AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A086996-002AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A086996-002AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A086996-002AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A086996-002AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A086996-002AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A086996-002AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A086996-002AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A086996-002AA1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
butalbital, aspirin, and caffeine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BUTALBITAL325 mg/1
ASPIRIN50 mg/1
CAFFEINE40 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
KHS0AZ4JVKInternal UNII lookup
R16CO5Y76EInternal UNII lookup
3G6A5W338EInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
238134Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e69d8bb1-ba09-42e2-8372-7f5e0a906174Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
7dea7767-9f52-b60a-5435-33cb9cc28baeProduct name420250124
6338270f-96cb-0ecb-6fbb-0a9bc78001f4Product name720250116
11939cf5-0ea7-5df5-5127-00a7ce07fd7fProduct name520250115
0ca83774-3f79-b837-5d6f-c210102f3bc8Product name620250114
88300afc-e1c4-ad17-c80b-4957f1b809a5Product name520250113
79e1734e-f721-4d46-978a-be382f771672Product name220230110
41b814f3-0166-1c53-c9ef-a0794c7daf9dProduct name320221110
a590be26-846c-8659-a5a1-fb25907965dcProduct name220221110
d7724692-1155-4cc8-a415-22f5fc4aec35Product name620220216
bde672ba-4805-28d0-1986-73543d41b412Product name220210201
2dc76302-91c0-4c35-ad78-99adfb049c4bProduct name120200603
103b151b-b17f-42ac-8624-3ef62f5e2975Product name220200507
e6065d4b-5ae1-476f-a40e-f2851cbb5d2bProduct name220180221
f212291f-05fe-9603-fc7e-bd73e38ce1e6Product name220161129
ade821ba-260a-47e2-bd89-743e27ac9906Product name120161121
182f9ab4-4ab5-c449-200f-87ce2ce8e550Product name220151105
9425d234-4ae1-4b53-adc6-8cc7af6dd657Product name120150929
2a21311a-89e2-0e83-2ebd-117f9798b2b2Product name120140508
332e86c3-7875-ca6e-f934-2206d2b31996Product name120140508
3ed6b849-48b8-8899-c288-6eeb396123b6Product name120140508
56625fcc-aa34-9d30-d0e9-1c1beb37ea21Product name120140508
7dfac40f-a405-cd2e-7c06-3059ec0e1092Product name120140508
9007e8a7-ff50-f9b9-7945-f2a1deadd94eProduct name120140508
96c2be53-8e44-452d-56a2-d255b2f1af2dProduct name120140508
bf8bd5f7-495f-4022-2780-7ded7ea7ea44Product name120140508
d223c173-c39b-d764-47d4-d671d3088815Product name120140508
e01133ad-4dcd-c7f3-454b-2ff569ee160aProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
62135-433-90butalbital, aspirin, and caffeine90 in 1 BOTTLECAPSULE903

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
62135-433-90EA - Each62135-4330ba66f2d-2b9a-4cb6-8c8c-ca2db1593f4512023-01-09

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
62135-433BUTALBITAL, ASPIRIN, AND CAFFEINE CAPSULE [CHARTWELL RX, LLC]2Current NDC, Legacy NDC, 1 package rows20231004_e69d8bb1-ba09-42e2-8372-7f5e0a906174.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
butalbital, aspirin, and caffeineBUTALBITAL, ASPIRIN, AND CAFFEINEChartwell RX, LLCe69d8bb1-ba09-42e2-8372-7f5e0a9061742025-12-09Warnings, Adverse reactionsExact identifier
application applno (ANDA): 086996
application number: ANDA086996
ndc (product): 62135-433
Butalbital, aspirin, and caffeineBUTALBITAL, ASPIRIN, AND CAFFEINESandoz Inc0e5e3842-fc6c-4a24-8e5c-522701f7c2912024-12-02Warnings, Adverse reactionsExact identifier
application applno (ANDA): 086996
application number: ANDA086996
Butalbital, aspirin, and caffeineBUTALBITAL, ASPIRIN, AND CAFFEINELannett Company, Inc.ba60b130-33cd-4db9-92a7-2cab8ded07372021-05-24Warnings, Adverse reactionsExact identifier
application applno (ANDA): 086996
application number: ANDA086996

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
238134butalbital 50 MG / aspirin 325 MG / caffeine 40 MG Oral CapsulePSNe69d8bb1-ba09-42e2-8372-7f5e0a9061743
238134aspirin 325 MG / butalbital 50 MG / caffeine 40 MG Oral CapsuleSCDe69d8bb1-ba09-42e2-8372-7f5e0a9061743
238134ASA 325 MG / butalbital 50 MG / Caffeine 40 MG Oral CapsuleSYe69d8bb1-ba09-42e2-8372-7f5e0a9061743

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
62135-433-906213504339090 CAPSULE in 1 BOTTLE (62135-433-90) 90 capsule2022-12-120000-00-00NoNoCurrent