Brimonidine Tartrate and Timolol Maleate

Product NDC
62332-706
11-digit product format
623320706
Labeler code
62332
Product ID
62332-706_5baf38df-3eb5-41cd-b533-cbf5652dd88d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Brimonidine Tartrate and Timolol Maleate
Dosage form
SOLUTION/ DROPS
Route
OPHTHALMIC
Labeler
Alembic Pharmaceuticals Inc.
Application
ANDA215230
Marketing category
ANDA
Marketing start
2023-08-25
Substance
BRIMONIDINE TARTRATE; TIMOLOL MALEATE
Active strength
2; 5 mg/mL; mg/mL
Pharmacologic classes
Adrenergic alpha-Agonists [MoA], Adrenergic beta-Antagonists [MoA], alpha-Adrenergic Agonist [EPC], beta-Adrenergic Blocker [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATEBRIMONIDINE TARTRATE; TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A215230-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-258072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-259b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215230-001BRIMONIDINE TARTRATE AND TIMOLOL MALEATE0.2%;EQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAB2023-08-25a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A215230-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215230-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A215230-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215230-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215230-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215230-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215230-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215230-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215230-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215230-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215230-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215230-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215230-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215230-001AB18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215230-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A215230-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A215230-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A215230-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A215230-001AB19b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215230-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Brimonidine Tartrate and Timolol Maleate
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BRIMONIDINE TARTRATE2 mg/mL
TIMOLOL MALEATE5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4S9CL2DY2HInternal UNII lookup
P8Y54F701RInternal UNII lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
10e79593-b991-4899-89fd-6fff7a213d81Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c6c0c444-a6ba-2fb5-a7bc-7f0443fa5791Product name420251208
8ec6541e-9842-115f-62bf-f7c9ab3aeddbProduct name320250805
73103a56-9f57-4f32-a306-a42bfa2fea36Product name120250505
425025fc-f910-4afe-815b-58d4486ed4f7Product name420250331
26c5ddae-5c69-622d-e599-5fd583634968Product name420250313
ee780602-134c-4c60-a2f0-e973ba549cd4Product name220250304
726062af-1135-4707-a1d7-57256991bbf9Product name220250226
39b7fcf4-8865-6d40-d24d-9b8c28bd6345Product name520250123
03f77cb2-b4ad-3c11-8781-787b5ece4291Product name320240507
273981e4-09e7-45cc-967c-554f628ededfProduct name320230627
97dad5a2-c524-a7b5-dede-82edefe9ce62Product name720220929
c93ffd9a-5bad-44d8-b5e5-16ef4d2fee72Product name120220316
d11e749b-f93e-0ce3-ceda-28fe03d8081dProduct name220190731
19c71a3d-ed9c-166b-a7e5-38c250c35631Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
62332-706-05Brimonidine Tartrate and Timolol Maleate5 mL in 1 BOTTLE, DROPPERSOLUTION/ DROPS54
62332-706-05Brimonidine Tartrate and Timolol Maleate1 in 1 CARTONSOLUTION/ DROPS14
62332-706-10Brimonidine Tartrate and Timolol Maleate10 mL in 1 BOTTLE, DROPPERSOLUTION/ DROPS104
62332-706-10Brimonidine Tartrate and Timolol Maleate1 in 1 CARTONSOLUTION/ DROPS14
62332-706-15Brimonidine Tartrate and Timolol Maleate15 mL in 1 BOTTLE, DROPPERSOLUTION/ DROPS154
62332-706-15Brimonidine Tartrate and Timolol Maleate1 in 1 CARTONSOLUTION/ DROPS14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
62332-706BRIMONIDINE TARTRATE AND TIMOLOL MALEATE SOLUTION/ DROPS [ALEMBIC PHARMACEUTICALS INC.]4Current NDC, 6 package rows20250427_10e79593-b991-4899-89fd-6fff7a213d81.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Brimonidine Tartrate and Timolol MaleateBRIMONIDINE TARTRATE AND TIMOLOL MALEATEAlembic Pharmaceuticals Inc.10e79593-b991-4899-89fd-6fff7a213d812026-04-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215230
application number: ANDA215230
ndc (product): 62332-706
Brimonidine Tartrate and Timolol MaleateBRIMONIDINE TARTRATE AND TIMOLOL MALEATEAlembic Pharmaceuticals Limitedb5d560b6-847e-4f09-b1ef-22e4deb8a2062023-08-31Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215230
application number: ANDA215230

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
861635brimonidine tartrate 0.2 % / timolol maleate 0.5 % Ophthalmic SolutionPSN10e79593-b991-4899-89fd-6fff7a213d814
861635brimonidine tartrate 2 MG/ML / timolol 5 MG/ML Ophthalmic SolutionSCD10e79593-b991-4899-89fd-6fff7a213d814
861635brimonidine tartrate 0.2 % / timolol 0.5 % (as timolol maleate 6.8 MG/ML) Ophthalmic SolutionSY10e79593-b991-4899-89fd-6fff7a213d814

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
62332-706-05623320706051 BOTTLE, DROPPER in 1 CARTON (62332-706-05) / 5 mL in 1 BOTTLE, DROPPER2023-08-25NoNoCurrent
62332-706-10623320706101 BOTTLE, DROPPER in 1 CARTON (62332-706-10) / 10 mL in 1 BOTTLE, DROPPER2023-08-25NoNoCurrent
62332-706-15623320706151 BOTTLE, DROPPER in 1 CARTON (62332-706-15) / 15 mL in 1 BOTTLE, DROPPER2023-08-25NoNoCurrent