XROMI

Product NDC
62484-0015
Requested package NDC
62484-0015-5
11-digit product format
624840015
Labeler code
62484
Product ID
62484-0015_6eb58656-a29b-4edb-966f-bc9a13a78775
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Hydroxyurea
Dosage form
SOLUTION
Route
ORAL
Labeler
Nova Laboratories, Ltd.
Application
NDA216593
Marketing category
NDA
Marketing start
2024-04-04
Substance
HYDROXYUREA
Active strength
100 mg/mL
Pharmacologic classes
Antimetabolite [EPC], Urea [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N216593-001XROMIHYDROXYUREA100MG/MLSOLUTION / ORALRLD, RS2024-04-04

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N216593-001124091562041-12-23Drug product2025-09-26

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N216593-001NP2027-04-04
N216593-001ODE-4702031-04-04

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-048072bd15b7f6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N216593-001XROMI100MG/MLSOLUTION / ORALRLD, RS2024-04-04a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N216593-001124091562041-12-23Drug product2025-09-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216593-001124091562041-12-23Drug product2025-09-2631067a03dcf5…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N216593-001124091562041-12-23Drug product2025-09-26a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N216593-001NP2027-04-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216593-001ODE-4702031-04-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216593-001NP2027-04-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216593-001ODE-4702031-04-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08N216593-001NP2027-04-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216593-001ODE-4702031-04-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216593-001NP2027-04-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216593-001ODE-4702031-04-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216593-001NP2027-04-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216593-001ODE-4702031-04-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216593-001NP2027-04-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216593-001ODE-4702031-04-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N216593-001NP2027-04-042680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N216593-001ODE-4702031-04-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N216593-001NP2027-04-045bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N216593-001ODE-4702031-04-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N216593-001NP2027-04-04d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N216593-001ODE-4702031-04-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N216593-001NP2027-04-04d06236e962d9…
2024-10-29 15:01 UTC2024-10N216593-001ODE-4702031-04-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N216593-001NP2027-04-0479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N216593-001ODE-4702031-04-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N216593-001ODE-4702031-04-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N216593-001ODE-4702031-04-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05N216593-001ODE-4702031-04-048072bd15b7f6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N216593-001NP2027-04-04a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N216593-001ODE-4702031-04-04a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
XROMI
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
HYDROXYUREA100 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
X6Q56QN5QCInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2682741Internal RxNorm lookup
2696079Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4b37d336-86da-4363-aef1-34a7d3ba973bAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
9be3ebe6-89e5-4e2f-8781-a389e7eb49e7Product name120250129
f76fb619-09b6-d149-3287-3661f7bc38cdProduct name320250124
62a0eedf-9497-47af-bccf-d51b8b15b067Product name120180307

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
62484-0015-4XROMI148 mL in 1 BOTTLESOLUTION14810
62484-0015-5XROMI1 in 1 CARTONSOLUTION110

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
62484-0015-4ML - Milliliter62484-0015111707d6-3307-4d5f-9438-5d129ab3488112025-03-04
62484-0015-5ML - Milliliter62484-0015a1a06064-f010-4988-891b-23d18d367aac12025-03-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
62484-0015XROMI (HYDROXYUREA) SOLUTION [NOVA LABORATORIES, LTD.]7Current NDC, 2 package rows20250105_4b37d336-86da-4363-aef1-34a7d3ba973b.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
XROMIHYDROXYUREANova Laboratories, Ltd.4b37d336-86da-4363-aef1-34a7d3ba973b2026-02-02Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 216593
application number: NDA216593
ndc (package): 62484-0015-5
ndc (product): 62484-0015
ndc11 (package): 62484001505

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2682741hydroxyurea 100 MG in 1 mL Oral SolutionPSN4b37d336-86da-4363-aef1-34a7d3ba973b10
2696079Xromi 100 MG in 1 mL Oral SolutionPSN4b37d336-86da-4363-aef1-34a7d3ba973b10
2696079hydroxyurea 100 MG/ML Oral Solution [Xromi]SBD4b37d336-86da-4363-aef1-34a7d3ba973b10
2682741hydroxyurea 100 MG/ML Oral SolutionSCD4b37d336-86da-4363-aef1-34a7d3ba973b10
2682741hydroxyurea 100 MG per 1 mL Oral SolutionSY4b37d336-86da-4363-aef1-34a7d3ba973b10
2696079Xromi 100 MG per 1 mL Oral SolutionSY4b37d336-86da-4363-aef1-34a7d3ba973b10

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
62484-0015-5624840015051 BOTTLE in 1 CARTON (62484-0015-5) / 148 mL in 1 BOTTLE (62484-0015-4) 1 bottle2024-04-04NoNoCurrent