Sulfamethoxazole and Trimethoprim

Product NDC
63187-008
11-digit product format
631870008
Labeler code
63187
Product ID
63187-008_2dd0e8d4-6ac3-433f-a41f-1e55d2b3f5ca
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Sulfamethoxazole and Trimethoprim
Dosage form
TABLET
Route
ORAL
Labeler
Proficient Rx LP
Application
ANDA076817
Marketing category
ANDA
Marketing start
2006-08-22
Substance
SULFAMETHOXAZOLE; TRIMETHOPRIM
Active strength
800; 160 mg/1; mg/1
Pharmacologic classes
Cytochrome P450 2C8 Inhibitors [MoA], Cytochrome P450 2C9 Inhibitors [MoA], Dihydrofolate Reductase Inhibitor Antibacterial [EPC], Dihydrofolate Reductase Inhibitors [MoA], Organic Cation Transporter 2 Inhibitors [MoA], Sulfonamide Antimicrobial [EPC], Sulfonamides [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIMSULFAMETHOXAZOLE; TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-07
A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIMSULFAMETHOXAZOLE; TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-07

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A076817-001AB
A076817-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-07caaa826d4ba7…
2026-08-18 06:07:402026-07A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-07caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-0731067a03dcf5…
2025-08-23 18:47 UTC2025-08A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-0703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-072680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-075bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-07d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-07d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-07d06236e962d9…
2024-10-29 15:01 UTC2024-10A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-07d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-0779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-0779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-07301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-07301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-071e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-071e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-078072bd15b7f6…
2024-05-31 18:47 UTC2024-05A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-078072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-075c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-075c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-075d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-075d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-074b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-074b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-0774a2ff9319b5…
2019-12-13 00:20 UTC2019-12A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-0774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076817-001SULFAMETHOXAZOLE AND TRIMETHOPRIM400MG;80MGTABLET / ORALAB2005-10-07bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A076817-002SULFAMETHOXAZOLE AND TRIMETHOPRIM800MG;160MGTABLET / ORALAB2005-10-07bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A076817-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A076817-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A076817-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A076817-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076817-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076817-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A076817-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A076817-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076817-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076817-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076817-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076817-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076817-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076817-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076817-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076817-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076817-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076817-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076817-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076817-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076817-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A076817-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076817-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076817-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076817-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076817-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076817-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076817-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076817-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A076817-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076817-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076817-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076817-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A076817-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076817-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A076817-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076817-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A076817-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076817-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A076817-002AB1bb7c543d1eb4…

Additional Listing Data#

Finished product
Yes
Brand name base
Sulfamethoxazole and Trimethoprim
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
SULFAMETHOXAZOLE800 mg/1
TRIMETHOPRIM160 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
JE42381TNVInternal UNII lookup
AN164J8Y0XInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
198335Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c407381f-3d8e-4fdf-9132-cd3968099296Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
4ce811b5-329e-27f8-b5ff-66d52b435c00Product name320240108
8d30c4f0-0228-cea4-e3aa-f19064c47f27Product name320221128
6e20c430-5e8f-85da-1b03-f7dbc0c51fadProduct name320190926
c1381fd7-868a-f499-ef90-8f6d3e3ee6b3Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
63187-008-06Sulfamethoxazole and Trimethoprim6 in 1 BOTTLETABLET68
63187-008-10Sulfamethoxazole and Trimethoprim10 in 1 BOTTLETABLET108
63187-008-14Sulfamethoxazole and Trimethoprim14 in 1 BOTTLETABLET148
63187-008-20Sulfamethoxazole and Trimethoprim20 in 1 BOTTLETABLET208
63187-008-28Sulfamethoxazole and Trimethoprim28 in 1 BOTTLETABLET288
63187-008-40Sulfamethoxazole and Trimethoprim40 in 1 BOTTLETABLET408

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
63187-008-10EA - Each63187-008df86133d-8270-44d0-bdbb-070d089c352612016-04-04
63187-008-14EA - Each63187-0082bc0407d-d977-4501-8e28-a4212305b4b512016-01-13
63187-008-20EA - Each63187-008f1337351-7f63-424f-902c-6f770f43744b12015-12-02
63187-008-28EA - Each63187-008d55661d3-8a5a-4ca3-9d6b-85871da4e0fe12017-04-05
63187-008-40EA - Each63187-0085d723f51-6e01-428f-a073-ef4dafc9e01a12023-08-08

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
SULFAMETHOXAZOLEACTIVE INGREDIENTJE42381TNVSULFAMETHOXAZOLE AND TRIMETHOPRIM TABLET [PROFICIENT RX LP]5
TRIMETHOPRIMACTIVE INGREDIENTAN164J8Y0XSULFAMETHOXAZOLE AND TRIMETHOPRIM TABLET [PROFICIENT RX LP]5
SULFAMETHOXAZOLEACTIVE MOIETYJE42381TNVSULFAMETHOXAZOLE AND TRIMETHOPRIM TABLET [PROFICIENT RX LP]5
TRIMETHOPRIMACTIVE MOIETYAN164J8Y0XSULFAMETHOXAZOLE AND TRIMETHOPRIM TABLET [PROFICIENT RX LP]5
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30SULFAMETHOXAZOLE AND TRIMETHOPRIM TABLET [PROFICIENT RX LP]5
SODIUM STARCH GLYCOLATE TYPE A POTATOINACTIVE INGREDIENT5856J3G2A2SULFAMETHOXAZOLE AND TRIMETHOPRIM TABLET [PROFICIENT RX LP]5
STARCH, CORNINACTIVE INGREDIENTO8232NY3SJSULFAMETHOXAZOLE AND TRIMETHOPRIM TABLET [PROFICIENT RX LP]5

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
63187-008SULFAMETHOXAZOLE AND TRIMETHOPRIM TABLET [PROFICIENT RX LP]8Current NDC, Legacy NDC, 6 package rows20221018_c407381f-3d8e-4fdf-9132-cd3968099296.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Sulfamethoxazole and TrimethoprimSULFAMETHOXAZOLE AND TRIMETHOPRIMProficient Rx LPc407381f-3d8e-4fdf-9132-cd39680992962022-10-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076817
application number: ANDA076817
ndc (product): 63187-008
Sulfamethoxazole and TrimethoprimSULFAMETHOXAZOLE AND TRIMETHOPRIMVista Pharmaceuticals, Inc.3edca473-8fdc-462a-b378-6c3279503a702020-01-22Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076817
application number: ANDA076817

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
198335sulfamethoxazole 800 MG / trimethoprim 160 MG Oral TabletPSNc407381f-3d8e-4fdf-9132-cd39680992968
198335sulfamethoxazole 800 MG / trimethoprim 160 MG Oral TabletSCDc407381f-3d8e-4fdf-9132-cd39680992968
198335SMX 800 MG / TMP 160 MG Oral TabletSYc407381f-3d8e-4fdf-9132-cd39680992968

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
63187-008-06631870008066 TABLET in 1 BOTTLE (63187-008-06) 6 tablet2018-11-010000-00-00NoNoCurrent
63187-008-106318700081010 TABLET in 1 BOTTLE (63187-008-10) 10 tablet2018-11-010000-00-00NoNoCurrent
63187-008-146318700081414 TABLET in 1 BOTTLE (63187-008-14) 14 tablet2018-11-010000-00-00NoNoCurrent
63187-008-206318700082020 TABLET in 1 BOTTLE (63187-008-20) 20 tablet2018-11-010000-00-00NoNoCurrent
63187-008-286318700082828 TABLET in 1 BOTTLE (63187-008-28) 28 tablet2018-11-010000-00-00NoNoCurrent
63187-008-406318700084040 TABLET in 1 BOTTLE (63187-008-40) 40 tablet2018-11-010000-00-00NoNoCurrent