Ketorolac Tromethamine

Product NDC
63187-628
11-digit product format
631870628
Labeler code
63187
Product ID
63187-628_ff9f9a3f-028e-49bd-8283-ad948d93a27f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ketorolac tromethamine
Dosage form
SOLUTION
Route
OPHTHALMIC
Labeler
Proficient Rx LP
Application
ANDA078434
Marketing category
ANDA
Marketing start
2009-11-05
Substance
KETOROLAC TROMETHAMINE
Active strength
5 mg/mL
Pharmacologic classes
Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitor [EPC], Cyclooxygenase Inhibitors [MoA], Nonsteroidal Anti-inflammatory Drug [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A078434-001KETOROLAC TROMETHAMINEKETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-05782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-0587673890dc5c…
2021-03-12 10:30 UTC2021-03A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-055aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-058869cabd3fbd…
2020-11-12 02:37 UTC2020-11A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-05c0c555d07b60…
2019-12-14 00:12 UTC2019-12A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-053f01610625f2…
2019-09-15 20:21 UTC2019-09A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-05b00525d2431f…
2019-07-19 19:46 UTC2019-07A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-05ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-053f0d92c62455…
2023-05-13 08:27 UTC2023-05A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMIC2009-11-05053a50430f4f…
2023-01-26 05:58 UTC2023-01A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-053bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-053a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-05f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A078434-001KETOROLAC TROMETHAMINE0.5%SOLUTION/DROPS / OPHTHALMICAT2009-11-05e64feba35796…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A078434-001AT15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A078434-001AT15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A078434-001AT14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A078434-001AT174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A078434-001AT1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A078434-001AT1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A078434-001AT187673890dc5c…
2021-03-12 10:30 UTC2021-03A078434-001AT15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A078434-001AT18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A078434-001AT1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A078434-001AT13f01610625f2…
2019-09-15 20:21 UTC2019-09A078434-001AT1b00525d2431f…
2019-07-19 19:46 UTC2019-07A078434-001AT1ea99ee380514…
2023-01-26 05:58 UTC2023-01A078434-001AT13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A078434-001AT13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A078434-001AT1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A078434-001AT1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A078434-001AT1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Ketorolac Tromethamine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
KETOROLAC TROMETHAMINE5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4EVE5946BQInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
860107Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
fc8ba956-4d3d-4f52-ac8e-89d52a480b48Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
6a38bd75-79e3-96c0-1204-08a0282902aeProduct name420250128
4d6e22a5-3693-6edf-0179-2ab93aecbadbProduct name920240724
03452e68-2506-686e-a908-f2381c778fc6Product name520240307
b5abe2e3-39a1-43eb-9bff-f3c1653fe3dfProduct name220190930
bb41bc3a-c643-93c9-055f-a8f48f363af3Product name220190219
4f6a8082-ae1e-0ff7-4dc0-77f9f0f7b70cProduct name120140508
8d3e992f-8ff7-c106-f7eb-1e2d5eb12025Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
63187-628-05Ketorolac Tromethamine5 mL in 1 BOTTLE, DROPPERSOLUTION54
63187-628-05Ketorolac Tromethamine1 in 1 CARTONSOLUTION14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
63187-628KETOROLAC TROMETHAMINE SOLUTION [PROFICIENT RX LP]4Current NDC, Legacy NDC, 2 package rows20210613_fc8ba956-4d3d-4f52-ac8e-89d52a480b48.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Ketorolac TromethamineKETOROLAC TROMETHAMINENuCare Pharmaceuticals,Inc.c2290fd1-2985-1275-e053-2995a90ad5fa2026-03-13Warnings, Adverse reactionsExact identifier
application applno (ANDA): 078434
application number: ANDA078434
Ketorolac TromethamineKETOROLAC TROMETHAMINEProficient Rx LPfc8ba956-4d3d-4f52-ac8e-89d52a480b482021-06-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 078434
application number: ANDA078434
ndc (product): 63187-628

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
860107ketorolac tromethamine 0.5 % Ophthalmic SolutionPSNfc8ba956-4d3d-4f52-ac8e-89d52a480b484
860107ketorolac tromethamine 5 MG/ML Ophthalmic SolutionSCDfc8ba956-4d3d-4f52-ac8e-89d52a480b484
860107ketorolac tromethamine 0.5 % Ophthalmic SolutionSYfc8ba956-4d3d-4f52-ac8e-89d52a480b484

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
63187-628-05631870628051 BOTTLE, DROPPER in 1 CARTON (63187-628-05) / 5 mL in 1 BOTTLE, DROPPER2018-12-010000-00-00NoNoCurrent