Cladribine

Product NDC
63323-140
11-digit product format
633230140
Labeler code
63323
Product ID
63323-140_77a36c8d-5dde-47a1-a50c-77239395cee2
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
CLADRIBINE
Dosage form
INJECTION
Route
INTRAVENOUS
Labeler
Fresenius Kabi USA, LLC
Application
ANDA076571
Marketing category
ANDA
Marketing start
2004-12-01
Substance
CLADRIBINE
Active strength
1 mg/mL
Pharmacologic classes
Purine Antimetabolite [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A076571-001CLADRIBINECLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A076571-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-228072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-225c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-225d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-224b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-2274a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-2287673890dc5c…
2021-03-12 10:30 UTC2021-03A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-225aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-228869cabd3fbd…
2020-11-12 02:37 UTC2020-11A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22c0c555d07b60…
2019-12-14 00:12 UTC2019-12A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-223f01610625f2…
2019-09-15 20:21 UTC2019-09A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22b00525d2431f…
2019-07-19 19:46 UTC2019-07A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-226a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-221c564ffb4f44…
2023-12-20 04:57 UTC2023-12A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-229b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-223f0d92c62455…
2023-05-13 08:27 UTC2023-05A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22053a50430f4f…
2023-01-26 05:58 UTC2023-01A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-223bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-223a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A076571-001CLADRIBINE1MG/MLINJECTABLE / INJECTIONAPRS2004-04-22cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A076571-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076571-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A076571-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076571-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076571-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076571-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076571-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076571-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076571-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076571-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076571-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076571-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076571-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076571-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076571-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076571-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076571-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076571-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076571-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076571-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A076571-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A076571-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A076571-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A076571-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A076571-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A076571-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A076571-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A076571-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A076571-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A076571-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A076571-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A076571-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A076571-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A076571-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A076571-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A076571-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A076571-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A076571-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A076571-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A076571-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Cladribine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CLADRIBINE1 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
47M74X9YT5Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
240754Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a2592a9b-bca6-4a5a-89c2-855a0634d5feAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
e6341a9e-3b90-6d63-7529-e3c0b6be164aProduct name220200511
21075a88-376d-46da-a075-a9797650ce34Product name120190702

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
63323-140-10Cladribine10 mL in 1 VIAL, SINGLE-DOSEINJECTION106
63323-140-10Cladribine1 in 1 CARTONINJECTION16

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
63323-140-10ML - Milliliter63323-1408facd4c4-bda6-4067-82b3-f4f3a69b420712012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
CLADRIBINEACTIVE INGREDIENT47M74X9YT5CLADRIBINE INJECTION [FRESENIUS KABI USA, LLC]3
CLADRIBINEACTIVE MOIETY47M74X9YT5CLADRIBINE INJECTION [FRESENIUS KABI USA, LLC]3
PHOSPHORIC ACIDINACTIVE INGREDIENTE4GA8884NNCLADRIBINE INJECTION [FRESENIUS KABI USA, LLC]3
SODIUM CHLORIDEINACTIVE INGREDIENT451W47IQ8XCLADRIBINE INJECTION [FRESENIUS KABI USA, LLC]3
SODIUM PHOSPHATE, DIBASICINACTIVE INGREDIENTGR686LBA74CLADRIBINE INJECTION [FRESENIUS KABI USA, LLC]3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
63323-140CLADRIBINE (CLADRIBINE) INJECTION [FRESENIUS KABI USA, LLC]6Current NDC, Legacy NDC, 2 package rows20241013_a2592a9b-bca6-4a5a-89c2-855a0634d5fe.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CladribineCLADRIBINEFresenius Kabi USA, LLCa2592a9b-bca6-4a5a-89c2-855a0634d5fe2024-10-10Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076571
application number: ANDA076571
ndc (product): 63323-140

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
240754cladribine 10 MG in 10 ML InjectionPSNa2592a9b-bca6-4a5a-89c2-855a0634d5fe6
24075410 ML cladribine 1 MG/ML InjectionSCDa2592a9b-bca6-4a5a-89c2-855a0634d5fe6
240754cladribine 10 MG per 10 ML InjectionSYa2592a9b-bca6-4a5a-89c2-855a0634d5fe6

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
63323-140-10633230140101 VIAL, SINGLE-DOSE in 1 CARTON (63323-140-10) / 10 mL in 1 VIAL, SINGLE-DOSE2004-12-010000-00-00NoNoCurrent