The Cure Oil-Free

Product NDC: 63730-222
11-digit product format: 637300222
Labeler code: 63730
Product ID: 63730-222_4afa4533-6921-4974-8b3c-b63533061088
Type: HUMAN OTC DRUG
Nonproprietary name: Octinoxate, Titanium Dioxide
Dosage form: CREAM
Route: TOPICAL
Labeler: Natura Bisse International SA
Application: part352
Marketing category: OTC MONOGRAPH FINAL
Marketing start: 2014-04-21
Marketing end: 0000-00-00
Substance: OCTINOXATE; TITANIUM DIOXIDE
Active strength: 2 g/50g; g/50g
NDC exclude flag: No
Listing certified through: 2019-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded product	product	63730-222		D	Discontinued by firm		2026-10-05
excluded package	package	63730-222	63730-222-01	D	Discontinued by firm		2026-10-05

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 42 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	63730-222-01	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	63730-222-01	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	63730-222-01	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	63730-222-01	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	63730-222-01	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	63730-222-01	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	63730-222-01	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	63730-222-01	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	63730-222-01	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	63730-222-01	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	63730-222-01	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	63730-222-01	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	63730-222-01	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	63730-222-01	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	63730-222-01	`1332a3947898…`	`d4bfe170f9cd…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded product	product		`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	63730-222-01	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded product	product		`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	63730-222-01	`86f5da6cb304…`	`a595104c45d7…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded product	product		`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	63730-222-01	`bd6a592717d7…`	`303034d00443…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded product	product		`8dfbde2a14a4…`	`c9ff85d89658…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded package	package	63730-222-01	`8dfbde2a14a4…`	`c9ff85d89658…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded product	product		`e2bbac7714bc…`	`27bdfed8d636…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded package	package	63730-222-01	`e2bbac7714bc…`	`27bdfed8d636…`
2020-06-10 20:45 UTC · source 2020-06-10	excluded product	product		`9bebd1f3094a…`	`5416666fcb17…`
2020-06-10 20:45 UTC · source 2020-06-10	excluded package	package	63730-222-01	`9bebd1f3094a…`	`5416666fcb17…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
63730-222-01	2025-12-26	C162847	48780-1	9d75b9d0-ffe8-f424-e053-dadaa90a57ce	0a781aec-656d-4d13-b20a-f3b1b443dc22
63730-222-01	2020-01-31	C162847	48780-1	9d75b9d0-ffe8-f424-e053-dadaa90a57ce	0a781aec-656d-4d13-b20a-f3b1b443dc22

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
OCTINOXATE	ACTIVE INGREDIENT	4Y5P7MUD51	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
TITANIUM DIOXIDE	ACTIVE INGREDIENT	15FIX9V2JP	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
OCTINOXATE	ACTIVE MOIETY	4Y5P7MUD51	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
TITANIUM DIOXIDE	ACTIVE MOIETY	15FIX9V2JP	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
.ALPHA.-TOCOPHEROL ACETATE	INACTIVE INGREDIENT	9E8X80D2L0	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
AESCULUS HIPPOCASTANUM SEED OIL	INACTIVE INGREDIENT	E0M52HIR1Y	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
ALLANTOIN	INACTIVE INGREDIENT	344S277G0Z	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
ALUMINUM HYDROXIDE	INACTIVE INGREDIENT	5QB0T2IUN0	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
AMMONIUM GLYCYRRHIZATE	INACTIVE INGREDIENT	3VRD35U26C	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
ARGININE	INACTIVE INGREDIENT	94ZLA3W45F	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
BIOTIN	INACTIVE INGREDIENT	6SO6U10H04	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
BROWN IRON OXIDE	INACTIVE INGREDIENT	1N032N7MFO	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
BUTYLPARABEN	INACTIVE INGREDIENT	3QPI1U3FV8	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
CAFFEINE	INACTIVE INGREDIENT	3G6A5W338E	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
CAPRYLIC/CAPRIC/LAURIC TRIGLYCERIDE	INACTIVE INGREDIENT	FJ1H6M2JG9	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
CETYL PEG/PPG-10/1 DIMETHICONE (HLB 2)	INACTIVE INGREDIENT	V2W71V8T0X	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
CITRIC ACID MONOHYDRATE	INACTIVE INGREDIENT	2968PHW8QP	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
CYCLOMETHICONE 5	INACTIVE INGREDIENT	0THT5PCI0R	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
DIISOPROPYL SEBACATE	INACTIVE INGREDIENT	J8T3X564IH	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
DIMETHICONE	INACTIVE INGREDIENT	92RU3N3Y1O	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
DIMETHICONOL (100000 CST)	INACTIVE INGREDIENT	OSA9UP217S	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
DIPHENYL DIMETHICONE (100 CST)	INACTIVE INGREDIENT	AG1ANB6B8O	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
EDETATE DISODIUM	INACTIVE INGREDIENT	7FLD91C86K	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
EGG PHOSPHOLIPIDS	INACTIVE INGREDIENT	1Z74184RGV	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
ETHYLHEXYLGLYCERIN	INACTIVE INGREDIENT	147D247K3P	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
ETHYLPARABEN	INACTIVE INGREDIENT	14255EXE39	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
GELATIN	INACTIVE INGREDIENT	2G86QN327L	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
GLYCERIN	INACTIVE INGREDIENT	PDC6A3C0OX	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
GLYCERYL LINOLEATE	INACTIVE INGREDIENT	4763AXI84L	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
GLYCERYL LINOLENATE	INACTIVE INGREDIENT	SGB6X4G86K	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
HYALURONATE SODIUM	INACTIVE INGREDIENT	YSE9PPT4TH	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
HYDROXYPROPYL .ALPHA.-CYCLODEXTRIN	INACTIVE INGREDIENT	ZFR0T80O4Y	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
LACTIC ACID	INACTIVE INGREDIENT	33X04XA5AT	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
LEPIDIUM SATIVUM SEED	INACTIVE INGREDIENT	WZM06UL78H	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
LEVOMENOL	INACTIVE INGREDIENT	24WE03BX2T	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
METHYLPARABEN	INACTIVE INGREDIENT	A2I8C7HI9T	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
NIACINAMIDE	INACTIVE INGREDIENT	25X51I8RD4	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
PALMITAMIDOPROPYLTRIMONIUM CHLORIDE	INACTIVE INGREDIENT	N2U96D202F	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
PALMITOYL LYSYLDIOXYMETHIONYLLYSINE	INACTIVE INGREDIENT	T7A529FB8O	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
PANTHENOL	INACTIVE INGREDIENT	WV9CM0O67Z	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
PEG-10 DIMETHICONE (600 CST)	INACTIVE INGREDIENT	8PR7V1SVM0	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
PENTYLENE GLYCOL	INACTIVE INGREDIENT	50C1307PZG	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
PHENOXYETHANOL	INACTIVE INGREDIENT	HIE492ZZ3T	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
PROPYLENE CARBONATE	INACTIVE INGREDIENT	8D08K3S51E	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
PROPYLPARABEN	INACTIVE INGREDIENT	Z8IX2SC1OH	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
SALIX ALBA BARK	INACTIVE INGREDIENT	205MXS71H7	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
SERINE	INACTIVE INGREDIENT	452VLY9402	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
SILICA DIMETHYL SILYLATE	INACTIVE INGREDIENT	EU2PSP0G0W	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
SODIUM CHLORIDE	INACTIVE INGREDIENT	451W47IQ8X	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
SODIUM CITRATE	INACTIVE INGREDIENT	1Q73Q2JULR	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
SODIUM LACTATE	INACTIVE INGREDIENT	TU7HW0W0QT	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
SORBITOL	INACTIVE INGREDIENT	506T60A25R	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
STEARALKONIUM HECTORITE	INACTIVE INGREDIENT	OLX698AH5P	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
STEARIC ACID	INACTIVE INGREDIENT	4ELV7Z65AP	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
TRIETHOXYCAPRYLYLSILANE	INACTIVE INGREDIENT	LDC331P08E	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
UREA	INACTIVE INGREDIENT	8W8T17847W	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
WATER	INACTIVE INGREDIENT	059QF0KO0R	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
YEAST	INACTIVE INGREDIENT	3NY3SM6B8U	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3
ZINC GLUCONATE	INACTIVE INGREDIENT	U6WSN5SQ1Z	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
63730-222	THE CURE OIL-FREE (OCTINOXATE, TITANIUM DIOXIDE) CREAM [NATURA BISSE INTERNATIONAL SA]	3	Legacy NDC	20140430_0a781aec-656d-4d13-b20a-f3b1b443dc22.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
4Y5P7MUD51	OCTINOXATE	83834-59-7	OCTINOXATE
15FIX9V2JP	TITANIUM DIOXIDE	13463-67-7	TITANIUM DIOXIDE

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
The Cure Oil-Free - Natura Bisse International SA	Natura Bisse International SA	2014-04-30	HUMAN OTC DRUG LABEL	3