Home NDC 64764-158-18 Actoplus Met
Product NDC 64764-158
Requested package NDC 64764-158-18
11-digit product format 647640158
Labeler code 64764
Product ID 64764-158_8bacb433-92b6-4285-9ed3-b49e46ec63fc
Type HUMAN PRESCRIPTION DRUG
Nonproprietary name pioglitazone and metformin hydrochloride
Dosage form TABLET, FILM COATED
Route ORAL
Labeler Takeda Pharmaceuticals America, Inc.
Application NDA021842
Marketing category NDA
Marketing start 2005-08-29
Substance PIOGLITAZONE HYDROCHLORIDE; METFORMIN HYDROCHLORIDE
Active strength 15; 850 mg/1; mg/1
Pharmacologic classes Biguanide [EPC], Biguanides [CS], Peroxisome Proliferator Receptor alpha Agonist [EPC], Peroxisome Proliferator Receptor gamma Agonist [EPC], Peroxisome Proliferator-activated Receptor alpha Agonists [MoA], Peroxisome Proliferator-activated Receptor gamma Agonists [MoA], Thiazolidinedione [EPC], Thiazolidinediones [CS]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Source provenance: Browse the complete Orange Book source catalog · source snapshot 43 .
Orange Book products# Current product rows page 1 of 1 · 2 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date N021842-001 ACTOPLUS MET METFORMIN HYDROCHLORIDE; PIOGLITAZONE HYDROCHLORIDE 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 N021842-002 ACTOPLUS MET METFORMIN HYDROCHLORIDE; PIOGLITAZONE HYDROCHLORIDE 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29
Therapeutic equivalence codes# Current TE-code rows page 1 of 1 · 1 matching rows.
Application-product, TE code table Application-product TE code N021842-002 AB
Orange Book patents# Current patent rows page 1 of 1 · 4 matching rows.
Application-product, Patent, Expiration table Application-product Patent Expiration Use code Coverage / status Submission date N021842-001 9101660 2027-01-22 Drug product 2015-09-10 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 N021842-002 9320714 2029-02-03 Drug product 2016-05-20
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Product history page 1 of 3 · 86 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-09-14 22:38:34 2026-08 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 84e616aacf4f…2026-09-14 22:38:34 2026-08 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 84e616aacf4f…2026-08-18 06:07:40 2026-07 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 caaa826d4ba7…2026-02-19 14:30 UTC 2026-02 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 d8e5a09893c0…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 d06236e962d9…2024-10-29 15:01 UTC 2024-10 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 79d66fd596c7…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 301d65b070ca…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 1e350fbaab3a…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** TABLET / ORAL RLD 2005-08-29 8072bd15b7f6…2024-05-31 18:47 UTC 2024-05 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 8072bd15b7f6…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE TABLET / ORAL RLD 2005-08-29 5c6f7cd8ea54…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 5c6f7cd8ea54…2022-04-08 23:34 UTC 2022-04 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE TABLET / ORAL AB RLD 2005-08-29 5d02ea3f76ae…2022-04-08 23:34 UTC 2022-04 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 5d02ea3f76ae…2022-04-04 05:41 UTC 2022-04 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE TABLET / ORAL AB RLD 2005-08-29 4b0b4de00fa7…2022-04-04 05:41 UTC 2022-04 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 4b0b4de00fa7…2019-12-13 00:20 UTC 2019-12 N021842-001 ACTOPLUS MET 500MG;EQ 15MG BASE TABLET / ORAL AB RLD 2005-08-29 74a2ff9319b5…2019-12-13 00:20 UTC 2019-12 N021842-002 ACTOPLUS MET 850MG;EQ 15MG BASE TABLET / ORAL AB RLD, RS 2005-08-29 74a2ff9319b5…
Observed Orange Book normalized TE history# Normalized TE history page 1 of 2 · 55 observed states.
Observed Orange Book patent history# Patent history page 1 of 5 · 172 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Patent Expiration Use code Coverage / status Submission date Source SHA-256 2026-09-14 22:38:34 2026-08 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 84e616aacf4f…2026-09-14 22:38:34 2026-08 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 84e616aacf4f…2026-09-14 22:38:34 2026-08 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 84e616aacf4f…2026-09-14 22:38:34 2026-08 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 84e616aacf4f…2026-08-18 06:07:40 2026-07 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 caaa826d4ba7…2026-02-19 14:30 UTC 2026-02 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N021842-001 9101660 2027-01-22 Drug product 2015-09-10 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N021842-001 9320714 2029-02-03 Drug product 2016-05-20 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N021842-002 9101660 2027-01-22 Drug product 2015-09-10 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N021842-002 9320714 2029-02-03 Drug product 2016-05-20 5bbf6a4d5a75…
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Actoplus Met
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength PIOGLITAZONE HYDROCHLORIDE 15 mg/1 METFORMIN HYDROCHLORIDE 850 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination JQT35NPK6C Internal UNII lookup 786Z46389E Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 861822 Internal RxNorm lookup 861824 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 64764-158-18 Actoplus Met 180 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 180 27 64764-158-41 Actoplus Met 4 in 1 TRAY TABLET, FILM COATED 4 27 64764-158-41 Actoplus Met 1 in 1 CARTON TABLET, FILM COATED 1 27 64764-158-60 Actoplus Met 60 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 60 27
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded metformin hydrochloride ACTIVE INGREDIENT 786Z46389E ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 PIOGLITAZONE HYDROCHLORIDE ACTIVE INGREDIENT JQT35NPK6C ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 metformin ACTIVE MOIETY 9100L32L2N ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 pioglitazone ACTIVE MOIETY X4OV71U42S ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 cellulose, microcrystalline INACTIVE INGREDIENT OP1R32D61U ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 croscarmellose sodium INACTIVE INGREDIENT M28OL1HH48 ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 hypromellose 2910 (6 MPA.S) INACTIVE INGREDIENT 0WZ8WG20P6 ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 magnesium stearate INACTIVE INGREDIENT 70097M6I30 ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 polyethylene glycol 8000 INACTIVE INGREDIENT Q662QK8M3B ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 POVIDONES INACTIVE INGREDIENT FZ989GH94E ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 talc INACTIVE INGREDIENT 7SEV7J4R1U ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 titanium dioxide INACTIVE INGREDIENT 15FIX9V2JP ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 14 METFORMIN HYDROCHLORIDE ACTIVE INGREDIENT 786Z46389E ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 PIOGLITAZONE HYDROCHLORIDE ACTIVE INGREDIENT JQT35NPK6C ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 METFORMIN ACTIVE MOIETY 9100L32L2N ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 PIOGLITAZONE ACTIVE MOIETY X4OV71U42S ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 CELLULOSE, MICROCRYSTALLINE INACTIVE INGREDIENT OP1R32D61U ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 CROSCARMELLOSE SODIUM INACTIVE INGREDIENT M28OL1HH48 ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 MAGNESIUM STEARATE INACTIVE INGREDIENT 70097M6I30 ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 POLYETHYLENE GLYCOL 8000 INACTIVE INGREDIENT Q662QK8M3B ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 POVIDONE INACTIVE INGREDIENT FZ989GH94E ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 TALC INACTIVE INGREDIENT 7SEV7J4R1U ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2 TITANIUM DIOXIDE INACTIVE INGREDIENT 15FIX9V2JP ACTOPLUS MET (PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.] 2
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 64764-158 ACTOPLUS MET (PIOGLITAZONE AND METFORMIN HYDROCHLORIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.] 27 Current NDC, Legacy NDC, 4 package rows 20250406_42e49120-6f3f-11db-9fe1-0800200c9a66.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 1 matching rows.
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Marketing start Marketing end Sample Exclude flag Status 64764-158-18 64764015818 180 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (64764-158-18) 2005-08-29 0000-00-00 No No Current