Methadone Hydrochloride

Product NDC
64850-604
11-digit product format
648500604
Labeler code
64850
Product ID
64850-604_6745a13f-b53a-4f0d-9c0a-bbef6343a8d3
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Methadone Hydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Elite Laboratories, Inc.
Application
ANDA210484
Marketing category
ANDA
Marketing start
2018-08-06
Substance
METHADONE HYDROCHLORIDE
Active strength
10 mg/1
Pharmacologic classes
Full Opioid Agonists [MoA], Opioid Agonist [EPC]
DEA schedule
CII
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A210484-001METHADONE HYDROCHLORIDEMETHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-02
A210484-002METHADONE HYDROCHLORIDEMETHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-02

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A210484-001AA
A210484-002AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-02011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-0231067a03dcf5…
2025-08-23 18:47 UTC2025-08A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-026a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-02fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-02b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-02b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-0203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-0203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-022680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-022680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-025bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-025bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-02d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-02d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-02d06236e962d9…
2024-10-29 15:01 UTC2024-10A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-02d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORAL2018-08-0279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORAL2018-08-0279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORAL2018-08-02301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORAL2018-08-02301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORAL2018-08-021e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORAL2018-08-021e350fbaab3a…
2024-05-31 18:47 UTC2024-05A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORAL2018-08-028072bd15b7f6…
2024-05-31 18:47 UTC2024-05A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORAL2018-08-028072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORAL2018-08-025c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORAL2018-08-025c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORAL2018-08-025d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORAL2018-08-025d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORAL2018-08-024b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORAL2018-08-024b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-0274a2ff9319b5…
2019-12-13 00:20 UTC2019-12A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-0274a2ff9319b5…
2022-03-09 01:35 UTC2022-03A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-02bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-02bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A210484-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2018-08-02782e0a99824c…
2021-12-28 21:50 UTC2021-12A210484-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2018-08-02782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A210484-001AA1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A210484-002AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210484-001AA131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210484-002AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A210484-001AA16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A210484-002AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210484-001AA1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210484-002AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210484-001AA1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210484-002AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210484-001AA103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210484-002AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210484-001AA12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210484-002AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210484-001AA15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210484-002AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210484-001AA1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210484-002AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210484-001AA1d06236e962d9…
2024-10-29 15:01 UTC2024-10A210484-002AA1d06236e962d9…
2019-12-13 00:20 UTC2019-12A210484-001AA174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A210484-002AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A210484-001AA1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A210484-002AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A210484-001AA1782e0a99824c…
2021-12-28 21:50 UTC2021-12A210484-002AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A210484-001AA187673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A210484-002AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A210484-001AA15aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03A210484-002AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A210484-001AA18869cabd3fbd…
2020-12-22 03:56 UTC2020-12A210484-002AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A210484-001AA1c0c555d07b60…
2020-11-12 02:37 UTC2020-11A210484-002AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A210484-001AA13f01610625f2…
2019-12-14 00:12 UTC2019-12A210484-002AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A210484-001AA1b00525d2431f…
2019-09-15 20:21 UTC2019-09A210484-002AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A210484-001AA1ea99ee380514…
2019-07-19 19:46 UTC2019-07A210484-002AA1ea99ee380514…

Additional Listing Data#

Finished product
Yes
Brand name base
Methadone Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METHADONE HYDROCHLORIDE10 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
229809935BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
864706Internal RxNorm lookup
864718Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
d702d32b-98b1-412d-934c-1cd96af4b95aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
bc6c52c8-e3e2-9042-21d0-6770dcf1a49bProduct name320250819
a48f0261-b6cc-12b3-49fd-ed131bc5aa96Product name420210902
00dcb24c-d95e-78f6-6c1b-4d7b709bb2b9Product name620200708
a6a96832-f31d-b458-45cb-abb8bd940b44Product name220200304

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
64850-604-01Methadone Hydrochloride100 in 1 BOTTLE, PLASTICTABLET10012

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
64850-604-01EA - Each64850-604fbc1757b-8105-4b56-adff-3579c519619f12025-11-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
64850-604METHADONE HYDROCHLORIDE TABLET [ELITE LABORATORIES, INC.]9Current NDC, 1 package rows20241024_d702d32b-98b1-412d-934c-1cd96af4b95a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Methadone HydrochlorideMETHADONE HYDROCHLORIDEElite Laboratories, Inc.d702d32b-98b1-412d-934c-1cd96af4b95a2025-12-08Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 210484
application number: ANDA210484
ndc (product): 64850-604

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
864706methadone HCl 10 MG Oral TabletPSNd702d32b-98b1-412d-934c-1cd96af4b95a12
864718methadone HCl 5 MG Oral TabletPSNd702d32b-98b1-412d-934c-1cd96af4b95a12
864706methadone hydrochloride 10 MG Oral TabletSCDd702d32b-98b1-412d-934c-1cd96af4b95a12
864718methadone hydrochloride 5 MG Oral TabletSCDd702d32b-98b1-412d-934c-1cd96af4b95a12

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
64850-604-0164850060401100 TABLET in 1 BOTTLE, PLASTIC (64850-604-01) 100 tablet2018-08-06NoNoCurrent