Axe

Product NDC: 64942-1185
11-digit product format: 649421185
Labeler code: 64942
Product ID: 64942-1185_8eaeaeac-b058-428b-abb6-4ad1f01ed950
Type: HUMAN OTC DRUG
Nonproprietary name: Pyrithione Zinc
Dosage form: SHAMPOO
Route: TOPICAL
Labeler: Conopco Inc. d/b/a Unilever
Application: part358H
Marketing category: OTC MONOGRAPH FINAL
Marketing start: 2009-08-02
Marketing end: 0000-00-00
Substance: PYRITHIONE ZINC
Active strength: 1 mL/100mL
NDC exclude flag: E
Listing certified through: 2018-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 4 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	64942-1185		I	Inactivated by FDA	2026-10-05
excluded package	package	64942-1185	64942-1185-1	I	Inactivated by FDA	2026-10-05
excluded package	package	64942-1185	64942-1185-2	I	Inactivated by FDA	2026-10-05
excluded package	package	64942-1185	64942-1185-3	I	Inactivated by FDA	2026-10-05

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 2 · 88 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	64942-1185-2	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	64942-1185-1	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	64942-1185-3	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	64942-1185-2	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	64942-1185-1	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	64942-1185-3	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	64942-1185-2	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	64942-1185-1	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	64942-1185-3	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	64942-1185-2	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	64942-1185-1	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	64942-1185-3	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	64942-1185-2	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	64942-1185-1	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	64942-1185-3	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	64942-1185-2	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	64942-1185-1	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	64942-1185-3	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	64942-1185-2	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	64942-1185-1	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	64942-1185-3	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	64942-1185-2	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	64942-1185-1	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	64942-1185-3	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	64942-1185-2	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	64942-1185-1	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	64942-1185-3	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	64942-1185-2	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	64942-1185-1	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	64942-1185-3	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	64942-1185-2	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	64942-1185-1	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	64942-1185-3	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	64942-1185-2	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	64942-1185-1	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	64942-1185-3	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	64942-1185-2	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	64942-1185-1	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	64942-1185-3	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	64942-1185-2	`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	64942-1185-1	`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	64942-1185-3	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	64942-1185-2	`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	64942-1185-1	`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	64942-1185-3	`1332a3947898…`	`d4bfe170f9cd…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
64942-1185-1	2020-01-31	C162847	48780-1	9d75b9d0-7927-f424-e053-dadaa90a57ce	Axe Freeze Anti-Dandruff shampoo+conditioner
64942-1185-2	2020-01-31	C162847	48780-1	9d75b9d0-7927-f424-e053-dadaa90a57ce	Axe Freeze Anti-Dandruff shampoo+conditioner
64942-1185-3	2020-01-31	C162847	48780-1	9d75b9d0-7927-f424-e053-dadaa90a57ce	Axe Freeze Anti-Dandruff shampoo+conditioner

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
64942-1185-1	AxeFreeze AntiDandruff	355 mL in 1 CONTAINER	SHAMPOO	355	1
64942-1185-2	AxeFreeze AntiDandruff	50 mL in 1 CONTAINER	SHAMPOO	50	1
64942-1185-3	AxeFreeze AntiDandruff	443 mL in 1 CONTAINER	SHAMPOO	443	1

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Pyrithione Zinc	ACTIVE INGREDIENT	R953O2RHZ5	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
Pyrithione	ACTIVE MOIETY	6GK82EC25D	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
CARBOMER HOMOPOLYMER TYPE C	INACTIVE INGREDIENT	4Q93RCW27E	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
CITRIC ACID MONOHYDRATE	INACTIVE INGREDIENT	2968PHW8QP	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
COCAMIDOPROPYL BETAINE	INACTIVE INGREDIENT	5OCF3O11KX	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
D&C RED NO. 33	INACTIVE INGREDIENT	9DBA0SBB0L	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
DMDM HYDANTOIN	INACTIVE INGREDIENT	BYR0546TOW	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
FD&C BLUE NO. 1	INACTIVE INGREDIENT	H3R47K3TBD	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
GLYCOL STEARATE	INACTIVE INGREDIENT	0324G66D0E	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE)	INACTIVE INGREDIENT	B16G315W7A	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
IODOPROPYNYL BUTYLCARBAMATE	INACTIVE INGREDIENT	603P14DHEB	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
MENTHOL	INACTIVE INGREDIENT	L7T10EIP3A	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
METHYLCHLOROISOTHIAZOLINONE	INACTIVE INGREDIENT	DEL7T5QRPN	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
METHYLISOTHIAZOLINONE	INACTIVE INGREDIENT	229D0E1QFA	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
MICA	INACTIVE INGREDIENT	V8A1AW0880	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
PPG-9	INACTIVE INGREDIENT	I29VQH0G0B	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
SODIUM CHLORIDE	INACTIVE INGREDIENT	451W47IQ8X	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
SODIUM LAURETH SULFATE	INACTIVE INGREDIENT	BPV390UAP0	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
TEA-DODECYLBENZENESULFONATE	INACTIVE INGREDIENT	8HM7ZD48HN	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
TITANIUM DIOXIDE	INACTIVE INGREDIENT	15FIX9V2JP	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
64942-1185	AXE FREEZE ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [CONOPCO INC. D/B/A UNILEVER]	1	Legacy NDC, 3 package rows	20110602_f4f3add3-9253-42e6-afe2-565c7ee01585.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R953O2RHZ5	PYRITHIONE ZINC	13463-41-7	PYRITHIONE ZINC

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	f4f3add3-9253-42e6-afe2-565c7ee01585	1
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	f4f3add3-9253-42e6-afe2-565c7ee01585	1
209884	zinc pyrithione 1 % Medicated Conditioner	SY	f4f3add3-9253-42e6-afe2-565c7ee01585	1
209884	zinc pyrithione 1 % Medicated Shampoo	SY	f4f3add3-9253-42e6-afe2-565c7ee01585	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Status
64942-1185-1	64942118501	355 mL in 1 CONTAINER	355 ml	Historical
64942-1185-2	64942118502	50 mL in 1 CONTAINER	50 ml	Historical
64942-1185-3	64942118503	443 mL in 1 CONTAINER	443 ml	Historical

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Axe Freeze Anti-Dandruff shampoo+conditioner	Conopco Inc. d/b/a Unilever \| Unilever Supply Chain Co. d/b/a Unilever	2011-06-02	HUMAN OTC DRUG LABEL	1

Axe