Ciprofloxacin Otic

Product NDC
64950-381
11-digit product format
649500381
Labeler code
64950
Product ID
64950-381_3f726b10-ef7b-47d6-96c9-e1a7ee5461d9
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Ciprofloxacin
Dosage form
SOLUTION/ DROPS
Route
AURICULAR (OTIC)
Labeler
Genus Lifesciences
Application
ANDA217887
Marketing category
ANDA
Marketing start
2024-12-01
Substance
CIPROFLOXACIN
Active strength
.5 mg/.25mL
Pharmacologic classes
Cytochrome P450 1A2 Inhibitors [MoA], Fluoroquinolone Antibacterial [EPC], Fluoroquinolones [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217887-001CIPROFLOXACIN HYDROCHLORIDECIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A217887-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-05caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-052680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-05d8e5a09893c0…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217887-001CIPROFLOXACIN HYDROCHLORIDEEQ 0.2% BASESOLUTION/DROPS / OTICAB2024-11-05a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A217887-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A217887-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217887-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217887-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217887-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217887-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217887-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217887-001AB12680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217887-001AB1d8e5a09893c0…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217887-001AB1a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217887-001CGT2025-06-1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217887-001CGT2025-06-116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217887-001CGT2025-06-11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217887-001CGT2025-06-11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217887-001CGT2025-06-1103ed91905a0d…

Additional Listing Data#

Finished product
Yes
Brand name base
Ciprofloxacin Otic
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CIPROFLOXACIN.5 mg/.25mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
5E8K9I0O4UInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
848956Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
51dde3f2-adb1-4ed8-83c6-1f63723a2529Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
ea50b939-d92a-4100-84f5-1c1089663837Product name220240705
90aab9f8-63f3-478d-8db8-951525a18ab1Product name120180814
200e1d3d-46da-4371-beed-747da3cb3ff8Product name120180702
9e453f34-aacb-44d5-a119-c0e3dc1fca2aProduct name120160622
01eecbfe-0b50-413b-8898-6905c89b6568Product name120151228
a3304bb6-ef4e-06df-d604-35f7e883ed6cProduct name120140508
abaf203f-619e-f265-559f-8c81af5cb1c2Product name120140508
de5ea793-ffd9-0308-b0ca-00d9967be4eeProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
64950-381-14Ciprofloxacin Otic0.25 mL in 1 VIALSOLUTION/ DROPS0.251
64950-381-14Ciprofloxacin Otic14 in 1 CARTONSOLUTION/ DROPS141

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
64950-381-14EA - Each64950-3819a842f14-175c-4ff4-aea6-93fdb49b243d12025-07-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
64950-381CIPROFLOXACIN OTIC (CIPROFLOXACIN) SOLUTION/ DROPS [GENUS LIFESCIENCES]1Current NDC, 2 package rows20250417_51dde3f2-adb1-4ed8-83c6-1f63723a2529.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Ciprofloxacin OticCIPROFLOXACINGenus Lifesciences51dde3f2-adb1-4ed8-83c6-1f63723a25292025-04-15Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217887
application number: ANDA217887
ndc (product): 64950-381

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
848956ciprofloxacin HCl 0.2 % Otic SolutionPSN51dde3f2-adb1-4ed8-83c6-1f63723a25291
848956ciprofloxacin 2 MG/ML Otic SolutionSCD51dde3f2-adb1-4ed8-83c6-1f63723a25291
848956ciprofloxacin 0.2 % Otic SolutionSY51dde3f2-adb1-4ed8-83c6-1f63723a25291

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
64950-381-146495003811414 VIAL in 1 CARTON (64950-381-14) / .25 mL in 1 VIAL14 vial2024-12-01NoNoCurrent