Protriptyline Hydrochloride

Product NDC
64980-159
11-digit product format
649800159
Labeler code
64980
Product ID
64980-159_995c0f12-2125-da56-e053-2995a90a8dfe
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Protriptyline Hydrochloride
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Rising Pharmaceuticals, Inc
Application
ANDA090462
Marketing category
ANDA
Marketing start
2010-06-11
Marketing end
0000-00-00
Substance
PROTRIPTYLINE HYDROCHLORIDE
Active strength
10 mg/1
Pharmacologic classes
Tricyclic Antidepressant [EPC]
NDC exclude flag
No
Listing certified through
2020-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct64980-159DDiscontinued by firm2026-08-10
excluded packagepackage64980-15964980-159-01DDiscontinued by firm2026-08-10

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 24 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage64980-159-01d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage64980-159-01f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-31excluded productproduct2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage64980-159-012ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproducta1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage64980-159-01a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage64980-159-01cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage64980-159-01cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage64980-159-01302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage64980-159-01ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage64980-159-010efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage64980-159-01ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage64980-159-01367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproduct557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage64980-159-01557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A090462-001PROTRIPTYLINE HYDROCHLORIDEPROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-03
A090462-002PROTRIPTYLINE HYDROCHLORIDEPROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-03

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A090462-001AB
A090462-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-03011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-0331067a03dcf5…
2025-08-23 18:47 UTC2025-08A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-036a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-03fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-03fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-03b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-03b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-0303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-0303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-032680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-032680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-035bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-035bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-03d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-03d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-03d06236e962d9…
2024-10-29 15:01 UTC2024-10A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-03d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-0379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-0379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-03301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-03301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-031e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-031e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-038072bd15b7f6…
2024-05-31 18:47 UTC2024-05A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-038072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-035c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-035c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-035d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-035d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-034b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-034b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-0374a2ff9319b5…
2019-12-13 00:20 UTC2019-12A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-0374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-03bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-03bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A090462-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2010-05-03782e0a99824c…
2021-12-28 21:50 UTC2021-12A090462-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2010-05-03782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A090462-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090462-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090462-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090462-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A090462-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090462-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090462-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090462-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090462-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090462-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090462-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090462-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090462-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090462-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090462-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090462-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090462-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090462-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090462-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A090462-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090462-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090462-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090462-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090462-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090462-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090462-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090462-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A090462-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090462-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090462-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090462-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A090462-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090462-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A090462-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090462-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A090462-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090462-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A090462-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A090462-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A090462-002AB1782e0a99824c…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
64980-159-01EA - Each64980-159a2c3d1e4-1197-4fdd-a0e2-626e35f1917c12012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
PROTRIPTYLINE HYDROCHLORIDEACTIVE INGREDIENT44665V00O8PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
PROTRIPTYLINEACTIVE MOIETY4NDU154T12PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
ANHYDROUS DIBASIC CALCIUM PHOSPHATEINACTIVE INGREDIENTL11K75P92JPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
ANHYDROUS LACTOSEINACTIVE INGREDIENT3SY5LH9PMKPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
CROSPOVIDONEINACTIVE INGREDIENT68401960MKPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
D&C YELLOW NO. 10INACTIVE INGREDIENT35SW5USQ3GPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
FD&C YELLOW NO. 6INACTIVE INGREDIENTH77VEI93A8PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
POLYETHYLENE GLYCOL 3350INACTIVE INGREDIENTG2M7P15E5PPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
POLYVINYL ALCOHOLINACTIVE INGREDIENT532B59J990PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
TALCINACTIVE INGREDIENT7SEV7J4R1UPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [RISING PHARMACEUTICALS, INC]5

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Protriptyline HydrochloridePROTRIPTYLINE HYDROCHLORIDESigmapharm Laboratories, LLCa023e637-bee9-8c86-e053-2a95a90aa4882023-01-10Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090462
application number: ANDA090462

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
64980-159-0164980015901100 TABLET, FILM COATED in 1 BOTTLE (64980-159-01) 2010-06-110000-00-00NoNoCurrent