CHLORTHALIDONE

Product NDC
64980-303
11-digit product format
649800303
Labeler code
64980
Product ID
64980-303_94ef7a73-3872-4d19-bdde-881862337783
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
CHLORTHALIDONE
Dosage form
TABLET
Route
ORAL
Labeler
Rising Pharma Holdings, Inc.
Application
ANDA206904
Marketing category
ANDA
Marketing start
2017-05-17
Marketing end
2027-01-31
Substance
CHLORTHALIDONE
Active strength
25 mg/1
Pharmacologic classes
Increased Diuresis [PE], Thiazide-like Diuretic [EPC]
NDC exclude flag
No
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A206904-001CHLORTHALIDONECHLORTHALIDONE25MGTABLET / ORALAB2017-03-30
A206904-002CHLORTHALIDONECHLORTHALIDONE50MGTABLET / ORALAB2017-03-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A206904-001AB
A206904-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-30d06236e962d9…
2024-10-29 15:01 UTC2024-10A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-3079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-30301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-301e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-308072bd15b7f6…
2024-05-31 18:47 UTC2024-05A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-305c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-305d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-304b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-3074a2ff9319b5…
2019-12-13 00:20 UTC2019-12A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-30bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A206904-001CHLORTHALIDONE25MGTABLET / ORALAB2017-03-30782e0a99824c…
2021-12-28 21:50 UTC2021-12A206904-002CHLORTHALIDONE50MGTABLET / ORALAB2017-03-30782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A206904-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A206904-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206904-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206904-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A206904-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A206904-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206904-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206904-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206904-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206904-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206904-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206904-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206904-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206904-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206904-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206904-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206904-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206904-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A206904-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A206904-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206904-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206904-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206904-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206904-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206904-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206904-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A206904-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A206904-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A206904-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A206904-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A206904-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A206904-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A206904-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A206904-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A206904-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A206904-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A206904-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A206904-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A206904-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A206904-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
CHLORTHALIDONE

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CHLORTHALIDONE25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
Q0MQD1073QInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197499Internal RxNorm lookup
197500Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
f96b2d0b-a141-4efb-8ccc-c447dfc6024aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
83fe98fe-2a14-448c-9029-41f7600d1b0aProduct name120260105
0450926f-f624-49c2-83be-42807e8fbcd5Product name120251113
8525e779-537f-e5cc-2515-089ecce5f50fProduct name920221128
faf41ef3-b4b3-a29e-3b26-07c3009003bfProduct name520220517
3f5e2da3-8b99-f714-3261-2c998ee07b05Product name120140508
7667d8e2-e5be-36e1-4de7-231aa7fdaf5cProduct name120140508

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
64980-303-01CHLORTHALIDONE100 in 1 BOTTLE, PLASTICTABLET1007
64980-303-10CHLORTHALIDONE1000 in 1 BOTTLE, PLASTICTABLET10007

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
64980-303-01EA - Each64980-3036945b338-95c9-41d8-a138-b7478faf0de012017-07-07
64980-303-10EA - Each64980-3035fbb5087-87ac-4c5c-809a-07259b6481d812017-07-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
64980-303CHLORTHALIDONE TABLET [RISING PHARMA HOLDINGS, INC.]7Current NDC, Legacy NDC, 2 package rows20250503_f96b2d0b-a141-4efb-8ccc-c447dfc6024a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CHLORTHALIDONECHLORTHALIDONERising Pharma Holdings, Inc.f96b2d0b-a141-4efb-8ccc-c447dfc6024a2025-04-29Warnings, Adverse reactionsExact identifier
application applno (ANDA): 206904
application number: ANDA206904
ndc (product): 64980-303
CHLORTHALIDONECHLORTHALIDONEAphena Pharma Solutions - Tennessee, LLCaa16c3fe-c00b-4b49-bfe3-3b3f93bd647a2020-10-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 206904
application number: ANDA206904

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197499chlorthalidone 25 MG Oral TabletPSNf96b2d0b-a141-4efb-8ccc-c447dfc6024a7
197500chlorthalidone 50 MG Oral TabletPSNf96b2d0b-a141-4efb-8ccc-c447dfc6024a7
197499chlorthalidone 25 MG Oral TabletSCDf96b2d0b-a141-4efb-8ccc-c447dfc6024a7
197500chlorthalidone 50 MG Oral TabletSCDf96b2d0b-a141-4efb-8ccc-c447dfc6024a7
197499chlorthalidone 25 MG Oral TabletPSN68f311ff-4ad3-430a-aa32-b56593f1cb015
197499chlorthalidone 25 MG Oral TabletPSN9b5c2ff4-d427-4f37-826a-7bac6abad7355
197499chlorthalidone 25 MG Oral TabletSCD68f311ff-4ad3-430a-aa32-b56593f1cb015
197499chlorthalidone 25 MG Oral TabletSCD9b5c2ff4-d427-4f37-826a-7bac6abad7355
197499chlorthalidone 25 MG Oral TabletPSN449a2f00-2860-4956-81ed-704567b1442a1
197499chlorthalidone 25 MG Oral TabletPSNaa16c3fe-c00b-4b49-bfe3-3b3f93bd647a1
197499chlorthalidone 25 MG Oral TabletSCD449a2f00-2860-4956-81ed-704567b1442a1
197499chlorthalidone 25 MG Oral TabletSCDaa16c3fe-c00b-4b49-bfe3-3b3f93bd647a1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
64980-303-0164980030301100 TABLET in 1 BOTTLE, PLASTIC (64980-303-01) 100 tablet2017-05-172027-01-31NoNoCurrent
64980-303-10649800303101000 TABLET in 1 BOTTLE, PLASTIC (64980-303-10) 1000 tablet2017-05-172027-01-31NoNoCurrent