Cyclobenzaprine Hydrochloride

Product NDC
64980-655
11-digit product format
649800655
Labeler code
64980
Product ID
64980-655_0512aebe-5f3a-4d41-9a41-7c37e001af75
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Cyclobenzaprine Hydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Rising Pharma Holdings, Inc.
Application
ANDA218936
Marketing category
ANDA
Marketing start
2025-02-19
Substance
CYCLOBENZAPRINE HYDROCHLORIDE
Active strength
5 mg/1
Pharmacologic classes
Centrally-mediated Muscle Relaxation [PE], Muscle Relaxant [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A218936-001CYCLOBENZAPRINE HYDROCHLORIDECYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-12
A218936-002CYCLOBENZAPRINE HYDROCHLORIDECYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-12
A218936-003CYCLOBENZAPRINE HYDROCHLORIDECYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-12

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A218936-001AB
A218936-002AB
A218936-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-12011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-1231067a03dcf5…
2025-08-23 18:47 UTC2025-08A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-126a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-12fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-12fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-12fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-12b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-12b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-12b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-1203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-122680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-12d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-12d06236e962d9…
2024-10-29 15:01 UTC2024-10A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-12d06236e962d9…
2024-10-29 15:01 UTC2024-10A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-12d06236e962d9…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218936-001CYCLOBENZAPRINE HYDROCHLORIDE5MGTABLET / ORALAB2024-09-12a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218936-002CYCLOBENZAPRINE HYDROCHLORIDE7.5MGTABLET / ORALAB2024-09-12a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218936-003CYCLOBENZAPRINE HYDROCHLORIDE10MGTABLET / ORALAB2024-09-12a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A218936-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A218936-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A218936-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218936-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218936-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218936-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A218936-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A218936-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A218936-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218936-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218936-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218936-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218936-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218936-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218936-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218936-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218936-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218936-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218936-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218936-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218936-003AB12680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218936-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218936-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218936-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A218936-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A218936-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A218936-003AB1d06236e962d9…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218936-001AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218936-002AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218936-003AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Cyclobenzaprine Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CYCLOBENZAPRINE HYDROCHLORIDE5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
0VE05JYS2PInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
828320Internal RxNorm lookup
828348Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6018b6e9-938d-4fc9-86d7-1fd1d7bfcc58Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
51048710-225c-aa41-d0e7-eed095d02838Product name420250331
c2c26dc9-7e16-fc02-7eba-6b46ed3515eeProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
64980-655-01Cyclobenzaprine Hydrochloride100 in 1 BOTTLETABLET1001
64980-655-10Cyclobenzaprine Hydrochloride1000 in 1 BOTTLETABLET10001
64980-655-50Cyclobenzaprine Hydrochloride500 in 1 BOTTLETABLET5001

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
64980-655-01EA - Each64980-65550a90abc-7e3a-4dab-bdd5-5ba43c78ea0f12025-06-13
64980-655-10EA - Each64980-6556233c600-84f0-4af1-a726-3012eea3c5e912025-06-13
64980-655-50EA - Each64980-6552e68b83c-fc04-42a7-a54c-ba7fa60c32ca12025-06-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
64980-655CYCLOBENZAPRINE HYDROCHLORIDE TABLET [RISING PHARMA HOLDINGS, INC.]1Current NDC, 3 package rows20250223_6018b6e9-938d-4fc9-86d7-1fd1d7bfcc58.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Cyclobenzaprine HydrochlorideCYCLOBENZAPRINE HYDROCHLORIDEREMEDYREPACK INC.34e57aff-dc4b-4631-9d57-31020244835d2026-07-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218936
application number: ANDA218936
Cyclobenzaprine HydrochlorideCYCLOBENZAPRINE HYDROCHLORIDEBryant Ranch Prepack6536b470-9a4e-4174-85b8-479f64cc32962025-07-14Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218936
application number: ANDA218936
FexmidCYCLOBENZAPRINE HYDROCHLORIDERising Pharma Holdings, Inc.41838966-de0b-4855-83b8-2ff6c764ed1f2025-04-07Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218936
application number: ANDA218936
Cyclobenzaprine HydrochlorideCYCLOBENZAPRINE HYDROCHLORIDERising Pharma Holdings, Inc.6018b6e9-938d-4fc9-86d7-1fd1d7bfcc582025-02-20Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218936
application number: ANDA218936
ndc (product): 64980-655

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
828348cyclobenzaprine HCl 10 MG Oral TabletPSN6018b6e9-938d-4fc9-86d7-1fd1d7bfcc581
828320cyclobenzaprine HCl 5 MG Oral TabletPSN6018b6e9-938d-4fc9-86d7-1fd1d7bfcc581
828348cyclobenzaprine hydrochloride 10 MG Oral TabletSCD6018b6e9-938d-4fc9-86d7-1fd1d7bfcc581
828320cyclobenzaprine hydrochloride 5 MG Oral TabletSCD6018b6e9-938d-4fc9-86d7-1fd1d7bfcc581

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
64980-655-0164980065501100 TABLET in 1 BOTTLE (64980-655-01) 100 tablet2025-02-19NoNoCurrent
64980-655-10649800655101000 TABLET in 1 BOTTLE (64980-655-10) 1000 tablet2025-02-19NoNoCurrent
64980-655-5064980065550500 TABLET in 1 BOTTLE (64980-655-50) 500 tablet2025-02-19NoNoCurrent