Promethazine Hydrochloride

Product NDC
65162-678
11-digit product format
651620678
Labeler code
65162
Product ID
65162-678_b501b0a4-d58d-4bf6-8ae1-5a7dae00dcad
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Promethazine
Dosage form
SOLUTION
Route
ORAL
Labeler
Amneal Pharmaceuticals LLC
Application
ANDA040882
Marketing category
ANDA
Marketing start
2009-12-30
Marketing end
0000-00-00
Substance
PROMETHAZINE HYDROCHLORIDE
Active strength
6 mg/5mL
Pharmacologic classes
Phenothiazine [EPC], Phenothiazines [CS]
NDC exclude flag
No
Listing certified through
2023-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct65162-678DDiscontinued by firm2026-08-03
excluded packagepackage65162-67865162-678-86DDiscontinued by firm2026-08-03
excluded packagepackage65162-67865162-678-90DDiscontinued by firm2026-08-03

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 15 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage65162-678-86367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage65162-678-90367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproduct557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage65162-678-86557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage65162-678-90557ba5c1ecfa…9c80585c8c6e…
2024-05-28 21:12 UTC · source 2024-05-28excluded productproduct8af77b9d5b6f…d9bbb34c5368…
2024-05-28 21:12 UTC · source 2024-05-28excluded packagepackage65162-678-868af77b9d5b6f…d9bbb34c5368…
2024-05-28 21:12 UTC · source 2024-05-28excluded packagepackage65162-678-908af77b9d5b6f…d9bbb34c5368…
2024-05-15 03:39 UTC · source 2024-05-14excluded productproduct834df4deac94…adcc014656a3…
2024-05-15 03:39 UTC · source 2024-05-14excluded packagepackage65162-678-86834df4deac94…adcc014656a3…
2024-05-15 03:39 UTC · source 2024-05-14excluded packagepackage65162-678-90834df4deac94…adcc014656a3…
2024-03-11 06:39 UTC · source 2024-03-08excluded productproduct1332a3947898…d4bfe170f9cd…
2024-03-11 06:39 UTC · source 2024-03-08excluded packagepackage65162-678-861332a3947898…d4bfe170f9cd…
2024-03-11 06:39 UTC · source 2024-03-08excluded packagepackage65162-678-901332a3947898…d4bfe170f9cd…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A040882-001PROMETHAZINE HYDROCHLORIDEPROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-30782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-3087673890dc5c…
2021-03-12 10:30 UTC2021-03A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-305aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-308869cabd3fbd…
2020-11-12 02:37 UTC2020-11A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-30c0c555d07b60…
2019-12-14 00:12 UTC2019-12A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-303f01610625f2…
2019-09-15 20:21 UTC2019-09A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-30b00525d2431f…
2019-07-19 19:46 UTC2019-07A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-30ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-306a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-301c564ffb4f44…
2023-12-20 04:57 UTC2023-12A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-309b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORAL2009-12-30a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-303f0d92c62455…
2023-05-13 08:27 UTC2023-05A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-30053a50430f4f…
2023-01-26 05:58 UTC2023-01A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-303bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-303a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-30f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-30e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A040882-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2009-12-30cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040882-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040882-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040882-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040882-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040882-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040882-001AA1782e0a99824c…
2021-03-12 10:30 UTC2021-03A040882-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A040882-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A040882-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A040882-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A040882-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A040882-001AA1ea99ee380514…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A040882-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A040882-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A040882-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A040882-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A040882-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A040882-001AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A040882-001AA1cb3db0bc1861…

FDA-Initiated Inactive NDC Indexing#

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
65162-678-90ML - Milliliter65162-678eaf3d751-129d-43f4-962e-dd27df317b9e12022-01-06

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
PROMETHAZINE HYDROCHLORIDEACTIVE INGREDIENTR61ZEH7I1IPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
PROMETHAZINEACTIVE MOIETYFF28EJQ494PROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
ALCOHOLINACTIVE INGREDIENT3K9958V90MPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
ASCORBIC ACIDINACTIVE INGREDIENTPQ6CK8PD0RPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
CITRIC ACID MONOHYDRATEINACTIVE INGREDIENT2968PHW8QPPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
D&C YELLOW NO. 10INACTIVE INGREDIENT35SW5USQ3GPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
EDETATE DISODIUMINACTIVE INGREDIENT7FLD91C86KPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
FD&C BLUE NO. 1INACTIVE INGREDIENTH3R47K3TBDPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
GLYCERININACTIVE INGREDIENTPDC6A3C0OXPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
SACCHARIN SODIUMINACTIVE INGREDIENTSB8ZUX40TYPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
SODIUM BENZOATEINACTIVE INGREDIENTOJ245FE5EUPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
SODIUM CITRATEINACTIVE INGREDIENT1Q73Q2JULRPROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6
SUCROSEINACTIVE INGREDIENTC151H8M554PROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
65162-678PROMETHAZINE HYDROCHLORIDE (PROMETHAZINE) SOLUTION [AMNEAL PHARMACEUTICALS LLC]12Legacy NDC20241031_afb16e94-03bf-4ea2-b2fe-e65f274e55a9.zip

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
65162-678-8665162067886118 mL in 1 BOTTLE (65162-678-86) 118 ml2009-12-300000-00-00NoNoCurrent
65162-678-9065162067890473 mL in 1 BOTTLE (65162-678-90) 473 ml2009-12-300000-00-00NoNoCurrent