Olopatadine Hydrochloride

Product NDC
65162-890
11-digit product format
651620890
Labeler code
65162
Product ID
65162-890_270f118a-97b1-420b-8504-bfc600008903
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Olopatadine Hydrochloride
Dosage form
SPRAY, METERED
Route
NASAL
Labeler
Amneal Pharmaceuticals LLC
Application
ANDA210901
Marketing category
ANDA
Marketing start
2020-02-03
Substance
OLOPATADINE HYDROCHLORIDE
Active strength
665 ug/1
Pharmacologic classes
Decreased Histamine Release [PE], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC], Histamine-1 Receptor Inhibitor [EPC], Mast Cell Stabilizer [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A210901-001OLOPATADINE HYDROCHLORIDEOLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A210901-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-284b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-2887673890dc5c…
2021-03-12 10:30 UTC2021-03A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASAL2020-01-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-28c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-289b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-283f0d92c62455…
2023-05-13 08:27 UTC2023-05A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-28053a50430f4f…
2023-01-26 05:58 UTC2023-01A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-283bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-283a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-28f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-28e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALAB2020-01-28cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A210901-001OLOPATADINE HYDROCHLORIDE0.665MG/SPRAYSPRAY, METERED / NASALABRS2020-01-28a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A210901-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A210901-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210901-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A210901-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210901-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210901-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210901-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210901-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210901-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210901-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210901-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210901-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210901-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210901-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A210901-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A210901-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A210901-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A210901-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A210901-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A210901-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A210901-001AB187673890dc5c…
2020-12-22 03:56 UTC2020-12A210901-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A210901-001AB1c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A210901-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A210901-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A210901-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A210901-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A210901-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A210901-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A210901-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A210901-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A210901-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A210901-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A210901-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A210901-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A210901-001AB1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A210901-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Olopatadine Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
OLOPATADINE HYDROCHLORIDE665 ug/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2XG66W44KFInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1797895Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
806e8d0f-ff42-4d6e-b840-49e3bf867cb5Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
726062af-1135-4707-a1d7-57256991bbf9Product name220250226
624001e0-0eba-4aac-a60c-c2ecb37d4f08Product name120220927
abab02bf-82c6-4b6c-8cb4-2ee39055aeb1Product name320210312
ee1438f7-d464-b7de-1b3a-aae378f7d672Product name820200121
4101b788-a943-3f81-6947-4acf7be2af4dProduct name420190703
ca2d4a1a-2b5b-4256-9aad-735e9282b3eeProduct name120150323
19c71a3d-ed9c-166b-a7e5-38c250c35631Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
65162-890-23Olopatadine Hydrochloride665 in 1 BOTTLE, SPRAYSPRAY, METERED66511
65162-890-23Olopatadine Hydrochloride1 in 1 CARTONSPRAY, METERED111

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
65162-890-23GM - Gram65162-89092b82a40-89b6-4127-9d15-4f32131c91e112021-04-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
65162-890OLOPATADINE HYDROCHLORIDE SPRAY, METERED [AMNEAL PHARMACEUTICALS LLC]11Current NDC, Legacy NDC, 2 package rows20241031_806e8d0f-ff42-4d6e-b840-49e3bf867cb5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Olopatadine HydrochlorideOLOPATADINE HYDROCHLORIDEAmneal Pharmaceuticals LLC806e8d0f-ff42-4d6e-b840-49e3bf867cb52021-04-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 210901
application number: ANDA210901
ndc (product): 65162-890

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1797895olopatadine HCl 665 MCG/ACTUAT Metered Dose Nasal SprayPSN806e8d0f-ff42-4d6e-b840-49e3bf867cb511
1797895olopatadine hydrochloride 0.665 MG/ACTUAT Metered Dose Nasal SpraySCD806e8d0f-ff42-4d6e-b840-49e3bf867cb511
1797895olopatadine hydrochloride 665 MCG/ACTUAT (equivalent to olopatadine 600 MCG/ACTUAT) Metered Dose Nasal SpraySY806e8d0f-ff42-4d6e-b840-49e3bf867cb511

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
65162-890-23651620890231 BOTTLE, SPRAY in 1 CARTON (65162-890-23) / 665 SPRAY, METERED in 1 BOTTLE, SPRAY2020-02-030000-00-00NoNoCurrent