EXENCE WHITE

Product NDC: 66273-0002
11-digit product format: 662730002
Labeler code: 66273
Product ID: 66273-0002_f8f3f653-d438-47d5-a846-918652369467
Type: HUMAN OTC DRUG
Nonproprietary name: HYDROQUINONE
Dosage form: LOTION
Route: CUTANEOUS
Labeler: AQUIMPEX SPA
Application: part358A
Marketing category: OTC MONOGRAPH NOT FINAL
Marketing start: 2011-07-12
Marketing end: 0000-00-00
Substance: HYDROQUINONE
Active strength: 4 mL/200mL
NDC exclude flag: E
Listing certified through: 2017-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded product	product	66273-0002		I	Inactivated by FDA		2026-10-15
excluded package	package	66273-0002	66273-0002-2	I	Inactivated by FDA		2026-10-15

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 44 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	66273-0002-2	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	66273-0002-2	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	66273-0002-2	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	66273-0002-2	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	66273-0002-2	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	66273-0002-2	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	66273-0002-2	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	66273-0002-2	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	66273-0002-2	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	66273-0002-2	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	66273-0002-2	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	66273-0002-2	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	66273-0002-2	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	66273-0002-2	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	66273-0002-2	`1332a3947898…`	`d4bfe170f9cd…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded product	product		`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	66273-0002-2	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded product	product		`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	66273-0002-2	`86f5da6cb304…`	`a595104c45d7…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded product	product		`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	66273-0002-2	`bd6a592717d7…`	`303034d00443…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded product	product		`8dfbde2a14a4…`	`c9ff85d89658…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded package	package	66273-0002-2	`8dfbde2a14a4…`	`c9ff85d89658…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded product	product		`e2bbac7714bc…`	`27bdfed8d636…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded package	package	66273-0002-2	`e2bbac7714bc…`	`27bdfed8d636…`
2020-06-10 20:45 UTC · source 2020-06-10	excluded product	product		`9bebd1f3094a…`	`5416666fcb17…`
2020-06-10 20:45 UTC · source 2020-06-10	excluded package	package	66273-0002-2	`9bebd1f3094a…`	`5416666fcb17…`
2019-12-08 06:16 UTC · source 2019-12-05	excluded product	product		`110d247fa046…`	`a55b01930146…`
2019-12-08 06:16 UTC · source 2019-12-05	excluded package	package	66273-0002-2	`110d247fa046…`	`a55b01930146…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
f52be47f-7aa7-46c0-b1fa-50c18dd50206	Product name	1	20201029
444b3e50-f226-46ef-bfca-2e7035d140cd	Product name	1	20190611
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
597b1cfd-7b31-5048-62be-ca5cd740da2f	Product name	1	20140508
85490a6b-2306-6bf2-c51b-eb63537dc2da	Product name	1	20140508
ec2149b3-5c6d-5344-f757-c86411073075	Product name	1	20140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
66273-0002-2	2019-10-29	C162847	48780-1	960f7f55-c098-8e05-e053-dbdaa90a074a	Exence White Body Milk Natural Clear Tone

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
66273-0002-1	EXENCE WHITE	500 mL in 1 BOTTLE, PLASTIC	LOTION	500		2
66273-0002-2	EXENCE WHITE	12 in 1 BOX	LOTION	12		2

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
HYDROQUINONE	ACTIVE INGREDIENT	XV74C1N1AE	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
HYDROQUINONE	ACTIVE MOIETY	XV74C1N1AE	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
BRASSICA RAPA VAR. RAPA OIL	INACTIVE INGREDIENT	N4G8379626	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
CARBOMER 934	INACTIVE INGREDIENT	Z135WT9208	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
CETYL ALCOHOL	INACTIVE INGREDIENT	936JST6JCN	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
CITRIC ACID MONOHYDRATE	INACTIVE INGREDIENT	2968PHW8QP	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
GLYCERYL MONOSTEARATE	INACTIVE INGREDIENT	230OU9XXE4	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
ISOPROPYL MYRISTATE	INACTIVE INGREDIENT	0RE8K4LNJS	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
LACTIC ACID	INACTIVE INGREDIENT	33X04XA5AT	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
METHYLPARABEN	INACTIVE INGREDIENT	A2I8C7HI9T	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
PALMITIC ACID	INACTIVE INGREDIENT	2V16EO95H1	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
POTASSIUM CETYL PHOSPHATE	INACTIVE INGREDIENT	03KCY6P7UT	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
PROPYLPARABEN	INACTIVE INGREDIENT	Z8IX2SC1OH	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
ROSEMARY	INACTIVE INGREDIENT	IJ67X351P9	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
SODIUM SULFITE	INACTIVE INGREDIENT	VTK01UQK3G	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
STEARIC ACID	INACTIVE INGREDIENT	4ELV7Z65AP	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2
WATER	INACTIVE INGREDIENT	059QF0KO0R	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
66273-0002	EXENCE WHITE (HYDROQUINONE) LOTION [AQUIMPEX SPA]	2	Legacy NDC, 2 package rows	20110714_3c465c60-e297-4f32-bd75-f668eac4b9ee.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
XV74C1N1AE	HYDROQUINONE	123-31-9	HYDROQUINONE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
153031	hydroquinone 2 % Topical Cream	PSN	3c465c60-e297-4f32-bd75-f668eac4b9ee	2
153031	hydroquinone 20 MG/ML Topical Cream	SCD	3c465c60-e297-4f32-bd75-f668eac4b9ee	2
153031	hydroquinone 2 % Topical Cream	SY	3c465c60-e297-4f32-bd75-f668eac4b9ee	2

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Status
66273-0002-1	66273000201	500 mL in 1 BOTTLE, PLASTIC	500 ml	Historical
66273-0002-2	66273000202	12 in 1 BOX		Historical