FLUOROURACIL

Product NDC
66530-249
Requested package NDC
66530-249-40
11-digit product format
665300249
Labeler code
66530
Product ID
66530-249_d71da1a5-c6a1-45a4-908f-0cd1a21f8537
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
fluorouracil
Dosage form
CREAM
Route
TOPICAL
Labeler
Spear Dermatology Products
Application
ANDA077524
Marketing category
ANDA
Marketing start
2008-04-11
Marketing end
2022-08-31
Substance
FLUOROURACIL
Active strength
50 mg/g
Pharmacologic classes
Nucleic Acid Synthesis Inhibitors [MoA],Nucleoside Metabolic Inhibitor [EPC]
NDC exclude flag
No
Listing certified through
0000-00-00
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage66530-24966530-249-40DDiscontinued by firm2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source dateSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-312ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-100efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A077524-001FLUOROURACILFLUOROURACIL5%CREAM / TOPICALAB2008-04-11

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A077524-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-112680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-115bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-1179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-111e350fbaab3a…
2024-05-31 18:47 UTC2024-05A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-118072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-115c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-115d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-114b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-1174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-1187673890dc5c…
2021-03-12 10:30 UTC2021-03A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-115aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-118869cabd3fbd…
2020-11-12 02:37 UTC2020-11A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11c0c555d07b60…
2019-12-14 00:12 UTC2019-12A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-113f01610625f2…
2019-09-15 20:21 UTC2019-09A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11b00525d2431f…
2019-07-19 19:46 UTC2019-07A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-116a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-111c564ffb4f44…
2023-12-20 04:57 UTC2023-12A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-119b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-113f0d92c62455…
2023-05-13 08:27 UTC2023-05A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11053a50430f4f…
2023-01-26 05:58 UTC2023-01A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-113bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-113a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A077524-001FLUOROURACIL5%CREAM / TOPICALAB2008-04-11e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A077524-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A077524-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077524-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A077524-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077524-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077524-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077524-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077524-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077524-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077524-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A077524-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077524-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077524-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077524-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A077524-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077524-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A077524-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A077524-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A077524-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A077524-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A077524-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A077524-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A077524-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A077524-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A077524-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A077524-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A077524-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A077524-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A077524-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A077524-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A077524-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A077524-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A077524-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A077524-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A077524-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A077524-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A077524-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A077524-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A077524-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A077524-001AB1e64feba35796…

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
7dc9482d-9b87-4471-9708-4f1b4585846bProduct name220250723
a2ca0bf8-8306-49cc-93a3-3e6e4137c7cbProduct name520250630
dc0d2364-4811-4665-a3ee-7ed8c7301465Product name220171219
62fb8671-1693-49d8-8aab-0c1bfdd6794eProduct name120151005
878ca466-81fd-9d24-1349-31baf36065c6Product name220150506
630d1bc2-ae6b-fd31-1264-c4733e788193Product name120140508

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
66530-249-40GM - Gram66530-249f20a9709-add6-4490-8d35-26394f8698fb12012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
FLUOROURACILACTIVE INGREDIENTU3P01618RTFLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
FLUOROURACILACTIVE MOIETYU3P01618RTFLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
CETYL ALCOHOLINACTIVE INGREDIENT936JST6JCNFLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TFLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
PETROLATUMINACTIVE INGREDIENT4T6H12BN9UFLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
POLYSORBATE 60INACTIVE INGREDIENTCAL22UVI4MFLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
PROPYLENE GLYCOLINACTIVE INGREDIENT6DC9Q167V3FLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
PROPYLPARABENINACTIVE INGREDIENTZ8IX2SC1OHFLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
STEARYL ALCOHOLINACTIVE INGREDIENT2KR89I4H1YFLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
WATERINACTIVE INGREDIENT059QF0KO0RFLUOROURACIL CREAM [SPEAR DERMATOLOGY PRODUCTS]2
FLUOROURACILACTIVE INGREDIENTU3P01618RTFLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
FLUOROURACILACTIVE INGREDIENTU3P01618RTFLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1
FLUOROURACILACTIVE MOIETYU3P01618RTFLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
FLUOROURACILACTIVE MOIETYU3P01618RTFLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1
CETYL ALCOHOLINACTIVE INGREDIENT936JST6JCNFLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
CETYL ALCOHOLINACTIVE INGREDIENT936JST6JCNFLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TFLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TFLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
PETROLATUMINACTIVE INGREDIENT4T6H12BN9UFLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
PETROLATUMINACTIVE INGREDIENT4T6H12BN9UFLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1
POLYSORBATE 60INACTIVE INGREDIENTCAL22UVI4MFLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1
POLYSORBATE 60INACTIVE INGREDIENTCAL22UVI4MFLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
PROPYLENE GLYCOLINACTIVE INGREDIENT6DC9Q167V3FLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
PROPYLENE GLYCOLINACTIVE INGREDIENT6DC9Q167V3FLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1
PROPYLPARABENINACTIVE INGREDIENTZ8IX2SC1OHFLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
PROPYLPARABENINACTIVE INGREDIENTZ8IX2SC1OHFLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1
STEARYL ALCOHOLINACTIVE INGREDIENT2KR89I4H1YFLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
STEARYL ALCOHOLINACTIVE INGREDIENT2KR89I4H1YFLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1
WATERINACTIVE INGREDIENT059QF0KO0RFLUOROURACIL CREAM [REBEL DISTRIBUTORS CORP]1
WATERINACTIVE INGREDIENT059QF0KO0RFLUOROURACIL (FLUOROURACIL) CREAM [PHYSICIANS TOTAL CARE, INC.]1

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
FLUOROURACILFLUOROURACILDr. Reddy's Labratories Inc.e137c766-1f7f-0251-90b9-450c3d4d78b92024-04-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 077524
application number: ANDA077524
FLUOROURACILFLUOROURACILMayne Pharma Inc.06475bd8-66d9-4f88-90e4-b367480dab392021-11-04Warnings, Adverse reactionsExact identifier
application applno (ANDA): 077524
application number: ANDA077524

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
105583fluorouracil 5 % Topical CreamPSN4d8f6f8f-a69a-48db-8ee1-3b23989cb11f1
105583fluorouracil 5 % Topical CreamPSNbf851a7f-902d-4f1d-9d19-fd9cd5701fcd1
105583fluorouracil 50 MG/ML Topical CreamSCD4d8f6f8f-a69a-48db-8ee1-3b23989cb11f1
105583fluorouracil 50 MG/ML Topical CreamSCDbf851a7f-902d-4f1d-9d19-fd9cd5701fcd1
1055835-5-fluorouracil 50 MG/ML Topical CreamSY4d8f6f8f-a69a-48db-8ee1-3b23989cb11f1
1055835-5-fluorouracil 50 MG/ML Topical CreamSYbf851a7f-902d-4f1d-9d19-fd9cd5701fcd1
1055835-FU 50 MG/ML Topical CreamSY4d8f6f8f-a69a-48db-8ee1-3b23989cb11f1
1055835-FU 50 MG/ML Topical CreamSYbf851a7f-902d-4f1d-9d19-fd9cd5701fcd1
105583fluorouracil 5 % Topical CreamSY4d8f6f8f-a69a-48db-8ee1-3b23989cb11f1
105583fluorouracil 5 % Topical CreamSYbf851a7f-902d-4f1d-9d19-fd9cd5701fcd1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
66530-249-406653002494040 g in 1 TUBE (66530-249-40) 40 g2008-04-112022-08-31NoNoCurrent