Orfadin

Product NDC
66658-120
11-digit product format
666580120
Labeler code
66658
Product ID
66658-120_f9c6cef5-fb71-4cb0-9793-5c23ac04572e
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Nitisinone
Dosage form
CAPSULE
Route
ORAL
Labeler
SWEDISH ORPHAN BIOVITRUM AB (PUBL)
Application
NDA021232
Marketing category
NDA
Marketing start
2016-07-01
Substance
NITISINONE
Active strength
20 mg/1
Pharmacologic classes
4-Hydroxyphenyl-Pyruvate Dioxygenase Inhibitor [EPC], Cytochrome P450 2C9 Inhibitors [MoA], Cytochrome P450 2E1 Inducers [MoA], Hydroxyphenylpyruvate Dioxygenase Inhibitors [MoA], Organic Anion Transporter 1 Inhibitors [MoA], Organic Anion Transporter 3 Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Additional Listing Data#

Finished product
Yes
Brand name base
Orfadin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
NITISINONE20 mg/1

Harmonized Identifiers#

Field, Values table
FieldValues
UniiK5BN214699
Rxcui351173, 351174, 351175, 352119, 352120, 352121, 1798999, 1799001

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
30289e20-d00d-4455-8aae-af8add8f10eeProduct name420240529
5b3e65b0-2e25-4346-b6a5-74172e0cd130Product name120170824
689eee6a-c9bd-41ef-86ac-b494143eb282Product name220160804

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
66658-120-60Orfadin1 in 1 CARTONCAPSULE114
66658-120-60Orfadin60 in 1 BOTTLE, PLASTICCAPSULE6014

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
66658-120-60EA - Each66658-120b0ec9c01-c1a2-4fbd-9860-87f0be38fc2e12016-09-02

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
66658-120ORFADIN (NITISINONE) CAPSULE [SWEDISH ORPHAN BIOVITRUM AB (PUBL)]14Current NDC, Legacy NDC, 2 package rows20220612_5d449b73-d503-4132-b978-d890491975df.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
351175nitisinone 10 MG Oral CapsulePSN5d449b73-d503-4132-b978-d890491975df14
351173nitisinone 2 MG Oral CapsulePSN5d449b73-d503-4132-b978-d890491975df14
1798999nitisinone 20 MG Oral CapsulePSN5d449b73-d503-4132-b978-d890491975df14
351174nitisinone 5 MG Oral CapsulePSN5d449b73-d503-4132-b978-d890491975df14
352121Orfadin 10 MG Oral CapsulePSN5d449b73-d503-4132-b978-d890491975df14
352119Orfadin 2 MG Oral CapsulePSN5d449b73-d503-4132-b978-d890491975df14
1799001Orfadin 20 MG Oral CapsulePSN5d449b73-d503-4132-b978-d890491975df14
352120Orfadin 5 MG Oral CapsulePSN5d449b73-d503-4132-b978-d890491975df14
352121nitisinone 10 MG Oral Capsule [Orfadin]SBD5d449b73-d503-4132-b978-d890491975df14
352119nitisinone 2 MG Oral Capsule [Orfadin]SBD5d449b73-d503-4132-b978-d890491975df14
1799001nitisinone 20 MG Oral Capsule [Orfadin]SBD5d449b73-d503-4132-b978-d890491975df14
352120nitisinone 5 MG Oral Capsule [Orfadin]SBD5d449b73-d503-4132-b978-d890491975df14
351175nitisinone 10 MG Oral CapsuleSCD5d449b73-d503-4132-b978-d890491975df14
351173nitisinone 2 MG Oral CapsuleSCD5d449b73-d503-4132-b978-d890491975df14
1798999nitisinone 20 MG Oral CapsuleSCD5d449b73-d503-4132-b978-d890491975df14
351174nitisinone 5 MG Oral CapsuleSCD5d449b73-d503-4132-b978-d890491975df14
352121Orfadin 10 MG Oral CapsuleSY5d449b73-d503-4132-b978-d890491975df14
352119Orfadin 2 MG Oral CapsuleSY5d449b73-d503-4132-b978-d890491975df14
1799001Orfadin 20 MG Oral CapsuleSY5d449b73-d503-4132-b978-d890491975df14
352120Orfadin 5 MG Oral CapsuleSY5d449b73-d503-4132-b978-d890491975df14

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
66658-120-60666580120601 BOTTLE, PLASTIC in 1 CARTON (66658-120-60) / 60 CAPSULE in 1 BOTTLE, PLASTIC2016-07-010000-00-00NoNoCurrent