Digoxin

Product NDC
66689-327
11-digit product format
666890327
Labeler code
66689
Product ID
66689-327_217566e2-b3e4-4c7b-9ff6-d1088df1526a
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Digoxin
Dosage form
SOLUTION
Route
ORAL
Labeler
VistaPharm, LLC
Application
ANDA213000
Marketing category
ANDA
Marketing start
2019-10-04
Substance
DIGOXIN
Active strength
.05 mg/mL
Pharmacologic classes
Cardiac Glycoside [EPC], Cardiac Glycosides [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A213000-001DIGOXINDIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A213000-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-048072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-045c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-045d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-044b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-0474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-0487673890dc5c…
2021-03-12 10:30 UTC2021-03A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-045aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-048869cabd3fbd…
2020-11-12 02:37 UTC2020-11A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04c0c555d07b60…
2019-12-14 00:12 UTC2019-12A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-043f01610625f2…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-046a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-041c564ffb4f44…
2023-12-20 04:57 UTC2023-12A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-049b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-043f0d92c62455…
2023-05-13 08:27 UTC2023-05A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04053a50430f4f…
2023-01-26 05:58 UTC2023-01A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-043bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-043a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A213000-001DIGOXIN0.05MG/MLELIXIR / ORALAA2019-10-04a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A213000-001AA1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A213000-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213000-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A213000-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213000-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213000-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213000-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213000-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213000-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213000-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213000-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213000-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213000-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213000-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A213000-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A213000-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A213000-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A213000-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A213000-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A213000-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A213000-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A213000-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A213000-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A213000-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A213000-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A213000-001AA13f01610625f2…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A213000-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A213000-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A213000-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A213000-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A213000-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A213000-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A213000-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A213000-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A213000-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A213000-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A213000-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A213000-001AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A213000-001AA1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A213000-001AA1a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2019-12-13 00:20 UTC2019-12A213000-001CGT2020-04-0174a2ff9319b5…
2020-12-22 03:56 UTC2020-12A213000-001CGT2020-04-018869cabd3fbd…
2020-11-12 02:37 UTC2020-11A213000-001CGT2020-04-01c0c555d07b60…
2019-12-14 00:12 UTC2019-12A213000-001CGT2020-04-013f01610625f2…

Additional Listing Data#

Finished product
Yes
Brand name base
Digoxin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DIGOXIN.05 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
73K4184T59Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
393245Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ce62a741-a981-4880-8ce3-93269606a730Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
20d84de3-cb46-44c4-9211-63e833fa2688Product name220221214
4d74103a-bb9b-9034-fbc8-dac635e6e729Product name320221117
5c3aa978-6f46-c7ca-2a83-b57385976beeProduct name120140508

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
66689-327-02Digoxin60 mL in 1 BOTTLE, GLASSSOLUTION6011
66689-327-02Digoxin1 in 1 CARTONSOLUTION111

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
66689-327-02ML - Milliliter66689-3273848bcee-da7f-459f-999b-8e540927d2d012019-11-12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
66689-327DIGOXIN SOLUTION [VISTAPHARM, LLC]9Current NDC, Legacy NDC, 2 package rows20240730_ce62a741-a981-4880-8ce3-93269606a730.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DigoxinDIGOXINVistaPharm, LLCce62a741-a981-4880-8ce3-93269606a7302025-06-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213000
application number: ANDA213000
ndc (product): 66689-327

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
393245digoxin 0.05 MG in 1 mL Oral SolutionPSNce62a741-a981-4880-8ce3-93269606a73011
393245digoxin 0.05 MG/ML Oral SolutionSCDce62a741-a981-4880-8ce3-93269606a73011
393245digoxin 50 MCG per 1 ML Oral SOlutionSYce62a741-a981-4880-8ce3-93269606a73011
393245digoxin 50 MCG/ML Oral SolutionSYce62a741-a981-4880-8ce3-93269606a73011

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
66689-327-02666890327021 BOTTLE, GLASS in 1 CARTON (66689-327-02) / 60 mL in 1 BOTTLE, GLASS2019-10-040000-00-00NoNoCurrent