Home NDC 66715-6433 Advil PM, TRAVEL BASIX
Product NDC 66715-6433
11-digit product format 667156433
Labeler code 66715
Product ID 66715-6433_27e68e85-e284-30b9-e063-6394a90aba9b
Type HUMAN OTC DRUG
Nonproprietary name Ibuprofen and Diphenhydramine citrate
Dosage form TABLET, COATED
Route ORAL
Labeler Lil' Drug Store Products, Inc.
Application NDA021394
Marketing category NDA
Marketing start 2022-11-15
Substance DIPHENHYDRAMINE CITRATE; IBUPROFEN
Active strength 38; 200 mg/1; mg/1
Pharmacologic classes Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC], Nonsteroidal Anti-inflammatory Drug [EPC]
NDC exclude flag No
Listing certified through 2026-12-31
Current FDA listing Yes Source provenance: Browse the complete Orange Book source catalog · source snapshot 1 .
Orange Book products# Current product rows page 1 of 1 · 1 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date N021394-001 ADVIL PM DIPHENHYDRAMINE CITRATE; IBUPROFEN 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Product history page 1 of 2 · 41 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-02-19 14:30 UTC 2026-02 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 8072bd15b7f6…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 5c6f7cd8ea54…2022-04-08 23:34 UTC 2022-04 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 5d02ea3f76ae…2022-04-04 05:41 UTC 2022-04 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 4b0b4de00fa7…2019-12-13 00:20 UTC 2019-12 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 74a2ff9319b5…2022-03-09 01:35 UTC 2022-03 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 bb7c543d1eb4…2021-12-28 21:50 UTC 2021-12 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 782e0a99824c…2021-05-05 16:15 UTC · 3 captures of this ZIP 2021-05 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 87673890dc5c…2021-03-12 10:30 UTC 2021-03 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 5aa47cf7b7d7…2020-12-22 03:56 UTC 2020-12 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 8869cabd3fbd…2020-11-12 02:37 UTC 2020-11 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 c0c555d07b60…2019-12-14 00:12 UTC 2019-12 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 3f01610625f2…2019-09-15 20:21 UTC 2019-09 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 b00525d2431f…2019-07-19 19:46 UTC 2019-07 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 ea99ee380514…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 6a51e52b5d6a…2024-02-18 07:12 UTC 2024-02 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 1c564ffb4f44…2023-12-20 04:57 UTC 2023-12 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 ea1830bbd6c7…2023-11-28 05:40 UTC · 2 captures of this ZIP 2023-11 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 a72a2bbeb626…2023-10-25 00:34 UTC · 2 captures of this ZIP 2023-10 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 9b2671bbb829…2023-07-15 15:27 UTC · 2 captures of this ZIP 2023-07 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 a67488948f0b…2023-06-13 01:57 UTC · 3 captures of this ZIP 2023-06 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 3f0d92c62455…2023-05-13 08:27 UTC 2023-05 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 053a50430f4f…2023-01-26 05:58 UTC 2023-01 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 3bdfa0b2c4d7…2022-11-12 20:34 UTC · 5 captures of this ZIP 2022-11 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 3a93d1ddd44b…2022-10-28 04:53 UTC 2022-10 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 f41ea6bd6efb…2022-09-29 23:25 UTC 2022-09 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 e64feba35796…2022-07-09 03:26 UTC · 3 captures of this ZIP 2022-07 N021394-001 ADVIL PM 38MG;200MG TABLET / ORAL RLD, RS 2005-12-21 cb3db0bc1861…
Observed Orange Book patent history# Captured, Edition, Application-product table Captured Edition Application-product Patent Expiration Use code Coverage / status Submission date Source SHA-256 2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N021394-001 8263647 2022-05-30 Drug product 5c6f7cd8ea54…2022-04-08 23:34 UTC 2022-04 N021394-001 8263647 2022-05-30 Drug product 5d02ea3f76ae…2022-04-04 05:41 UTC 2022-04 N021394-001 8263647 2022-05-30 Drug product 4b0b4de00fa7…2019-12-13 00:20 UTC 2019-12 N021394-001 8263647 2022-05-30 Drug product 74a2ff9319b5…2022-03-09 01:35 UTC 2022-03 N021394-001 8263647 2022-05-30 Drug product bb7c543d1eb4…2021-12-28 21:50 UTC 2021-12 N021394-001 8263647 2022-05-30 Drug product 782e0a99824c…2021-05-05 16:15 UTC · 3 captures of this ZIP 2021-05 N021394-001 8263647 2022-05-30 Drug product 87673890dc5c…2021-03-12 10:30 UTC 2021-03 N021394-001 8263647 2022-05-30 Drug product 5aa47cf7b7d7…2020-12-22 03:56 UTC 2020-12 N021394-001 8263647 2022-05-30 Drug product 8869cabd3fbd…2020-11-12 02:37 UTC 2020-11 N021394-001 8263647 2022-05-30 Drug product c0c555d07b60…2019-12-14 00:12 UTC 2019-12 N021394-001 8263647 2022-05-30 Drug product 3f01610625f2…2019-09-15 20:21 UTC 2019-09 N021394-001 8263647 2022-05-30 Drug product b00525d2431f…2019-07-19 19:46 UTC 2019-07 N021394-001 8263647 2022-05-30 Drug product ea99ee380514…2023-01-26 05:58 UTC 2023-01 N021394-001 8263647 2022-05-30 Drug product 3bdfa0b2c4d7…2022-11-12 20:34 UTC · 5 captures of this ZIP 2022-11 N021394-001 8263647 2022-05-30 Drug product 3a93d1ddd44b…2022-10-28 04:53 UTC 2022-10 N021394-001 8263647 2022-05-30 Drug product f41ea6bd6efb…2022-09-29 23:25 UTC 2022-09 N021394-001 8263647 2022-05-30 Drug product e64feba35796…2022-07-09 03:26 UTC · 3 captures of this ZIP 2022-07 N021394-001 8263647 2022-05-30 Drug product cb3db0bc1861…
Additional Listing Data#
Finished product Yes
Brand name base Advil PM, TRAVEL BASIX
Listing expiration 2026-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength IBUPROFEN 38 mg/1 DIPHENHYDRAMINE CITRATE 200 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination WK2XYI10QM Internal UNII lookup 4OD433S209 Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 895664 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# FDA-Initiated Inactive NDC Indexing# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 66715-6433-2 Advil PM, TRAVEL BASIX 2 in 1 POUCH TABLET, COATED 2 12 66715-6433-2 Advil PM, TRAVEL BASIX 2 in 1 CARTON TABLET, COATED 2 12
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded Diphenhydramine citrate ACTIVE INGREDIENT 4OD433S209 ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 Ibuprofen ACTIVE INGREDIENT WK2XYI10QM ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 Diphenhydramine ACTIVE MOIETY 8GTS82S83M ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 Ibuprofen ACTIVE MOIETY WK2XYI10QM ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 aluminum oxide INACTIVE INGREDIENT LMI26O6933 ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 calcium stearate INACTIVE INGREDIENT 776XM7047L ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 carnauba wax INACTIVE INGREDIENT R12CBM0EIZ ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 cellulose, microcrystalline INACTIVE INGREDIENT OP1R32D61U ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 croscarmellose sodium INACTIVE INGREDIENT M28OL1HH48 ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 FD&C blue no. 2 INACTIVE INGREDIENT L06K8R7DQK ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 glyceryl dibehenate INACTIVE INGREDIENT R8WTH25YS2 ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 hypromelloses INACTIVE INGREDIENT 3NXW29V3WO ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 lactose monohydrate INACTIVE INGREDIENT EWQ57Q8I5X ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 polydextrose INACTIVE INGREDIENT VH2XOU12IE ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 polyethylene glycols INACTIVE INGREDIENT 3WJQ0SDW1A ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 silicon dioxide INACTIVE INGREDIENT ETJ7Z6XBU4 ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 sodium lauryl sulfate INACTIVE INGREDIENT 368GB5141J ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 starch, corn INACTIVE INGREDIENT O8232NY3SJ ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 stearic acid INACTIVE INGREDIENT 4ELV7Z65AP ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2 titanium dioxide INACTIVE INGREDIENT 15FIX9V2JP ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 2
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 66715-6433 ADVIL PM (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED ADVIL PM, TRAVEL BASIX (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED ADVIL PM, CVP HEALTH (IBUPROFEN AND DIPHENHYDRAMINE CITRATE) TABLET, COATED [LIL' DRUG STORE PRODUCTS, INC.] 12 Current NDC, 2 package rows 20241219_b876bb40-a38b-445a-bc8a-466b3bfe166d.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 5 matching rows.
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Sample Exclude flag Status 66715-6433-2 66715643302 2 POUCH in 1 CARTON (66715-6433-2) / 2 TABLET, COATED in 1 POUCH 2 pouch 2022-11-15 No No Current