CILOXAN

Product NDC
66758-071
11-digit product format
667580071
Labeler code
66758
Product ID
66758-071_930a2e4b-dcac-4a27-a073-fd21622c1666
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ciprofloxacin hydrochloride
Dosage form
OINTMENT
Route
OPHTHALMIC
Labeler
Sandoz Inc
Application
NDA020369
Marketing category
NDA
Marketing start
1998-06-02
Substance
CIPROFLOXACIN HYDROCHLORIDE
Active strength
3 mg/g
Pharmacologic classes
Cytochrome P450 1A2 Inhibitors [MoA], Fluoroquinolone Antibacterial [EPC], Fluoroquinolones [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020369-001CILOXANCIPROFLOXACIN HYDROCHLORIDEEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-3087673890dc5c…
2021-03-12 10:30 UTC2021-03N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-305aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-308869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-303f01610625f2…
2019-09-15 20:21 UTC2019-09N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30b00525d2431f…
2019-07-19 19:46 UTC2019-07N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-306a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-301c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-309b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-303f0d92c62455…
2023-05-13 08:27 UTC2023-05N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30053a50430f4f…
2023-01-26 05:58 UTC2023-01N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-303bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-303a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020369-001CILOXANEQ 0.3% BASEOINTMENT / OPHTHALMICRLD, RS1998-03-30e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
CILOXAN
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CIPROFLOXACIN HYDROCHLORIDE3 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4BA73M5E37Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
213307Internal RxNorm lookup
309306Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
09ca5374-2a16-4a95-91b3-70591d78254eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
ea50b939-d92a-4100-84f5-1c1089663837Product name220240705
90aab9f8-63f3-478d-8db8-951525a18ab1Product name120180814
200e1d3d-46da-4371-beed-747da3cb3ff8Product name120180702
9e453f34-aacb-44d5-a119-c0e3dc1fca2aProduct name120160622
01eecbfe-0b50-413b-8898-6905c89b6568Product name120151228
a3304bb6-ef4e-06df-d604-35f7e883ed6cProduct name120140508
abaf203f-619e-f265-559f-8c81af5cb1c2Product name120140508
de5ea793-ffd9-0308-b0ca-00d9967be4eeProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
66758-071-38CILOXAN3.5 g in 1 TUBEOINTMENT3.52

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
66758-071-38GM - Gram66758-071d7d7e4cf-f716-46ba-87ff-35ab00b300b912025-05-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
66758-071CILOXAN (CIPROFLOXACIN HYDROCHLORIDE) OINTMENT [SANDOZ INC]2Current NDC, 1 package rows20250413_09ca5374-2a16-4a95-91b3-70591d78254e.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CILOXANCIPROFLOXACIN HYDROCHLORIDESandoz Inc09ca5374-2a16-4a95-91b3-70591d78254e2024-07-30Warnings, Adverse reactionsExact identifier
application applno (NDA): 020369
application number: NDA020369
ndc (product): 66758-071

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
213307Ciloxan 0.3 % Ophthalmic OintmentPSN09ca5374-2a16-4a95-91b3-70591d78254e2
309306ciprofloxacin HCl 0.3 % Ophthalmic OintmentPSN09ca5374-2a16-4a95-91b3-70591d78254e2
213307ciprofloxacin 0.003 MG/MG Ophthalmic Ointment [Ciloxan]SBD09ca5374-2a16-4a95-91b3-70591d78254e2
309306ciprofloxacin 0.003 MG/MG Ophthalmic OintmentSCD09ca5374-2a16-4a95-91b3-70591d78254e2
213307Ciloxan 0.003 MG/MG Ophthalmic OintmentSY09ca5374-2a16-4a95-91b3-70591d78254e2
213307Ciloxan 0.3 % Ophthalmic OintmentSY09ca5374-2a16-4a95-91b3-70591d78254e2
309306ciprofloxacin 0.3 % Ophthalmic OintmentSY09ca5374-2a16-4a95-91b3-70591d78254e2

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
66758-071-38667580071383.5 g in 1 TUBE (66758-071-38) 3.5 g2025-03-28NoNoCurrent