Xenazine

Product NDC
67386-422
Requested package NDC
67386-422-01
11-digit product format
673860422
Labeler code
67386
Product ID
67386-422_6f524695-2fc1-4c54-9212-69cff22cdfa7
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
tetrabenazine
Dosage form
TABLET
Route
ORAL
Labeler
Lundbeck Pharmaceuticals LLC
Application
NDA021894
Marketing category
NDA
Marketing start
2008-11-24
Substance
TETRABENAZINE
Active strength
25 mg/1
Pharmacologic classes
Vesicular Monoamine Transporter 2 Inhibitor [EPC], Vesicular Monoamine Transporter 2 Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 2 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopeProduct NDCPackage NDCCodeStatusReporting periodArchiveSnapshotSource SHA-256
2022-04-09 23:13 UTC · source 2022-04-08excluded packagepackage67386-42267386-422-01IInactivated by FDAexcluded / ndc_excluded.zip86f5da6cb304…a595104c45d7…
2022-04-04 05:40 UTC · source 2022-04-01excluded packagepackage67386-42267386-422-01IInactivated by FDAexcluded / ndc_excluded.zipbd6a592717d7…303034d00443…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021894-001XENAZINETETRABENAZINE12.5MGTABLET / ORALABRLD2008-08-15
N021894-002XENAZINETETRABENAZINE25MGTABLET / ORALABRLD, RS2008-08-15

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N021894-001AB
N021894-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-15011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-15b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-1503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-1503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-152680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-152680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-155bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-155bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-15d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-15d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-15d06236e962d9…
2024-10-29 15:01 UTC2024-10N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-15d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-1579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-1579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-15301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-15301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-151e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-151e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-158072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-158072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-155c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-155c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-155d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-155d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-154b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-154b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-1574a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-1574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-15bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-15bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021894-001XENAZINE12.5MGTABLET / ORALABRLD2008-08-15782e0a99824c…
2021-12-28 21:50 UTC2021-12N021894-002XENAZINE25MGTABLET / ORALABRLD, RS2008-08-15782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N021894-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021894-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021894-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021894-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021894-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021894-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021894-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021894-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021894-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021894-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021894-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021894-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021894-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021894-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021894-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021894-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021894-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021894-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021894-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N021894-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021894-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021894-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021894-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021894-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021894-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021894-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021894-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021894-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021894-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021894-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021894-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021894-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021894-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021894-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021894-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021894-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021894-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021894-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021894-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12N021894-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Xenazine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TETRABENAZINE25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
Z9O08YRN8OInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
199592Internal RxNorm lookup
805462Internal RxNorm lookup
805464Internal RxNorm lookup
805466Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ac768bab-8afa-4446-bc7f-caeeffec0cdaAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
dd868135-b25c-abb7-9326-3e7691e6893fProduct name820200611

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
67386-422-01Xenazine112 in 1 BOTTLETABLET11221

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
67386-422-01EA - Each67386-42251455ecd-9fc9-4cac-ba34-f122c8c61ac312012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
TETRABENAZINEACTIVE INGREDIENTZ9O08YRN8OXENAZINE (TETRABENAZINE) TABLET [LUNDBECK INC.]9
TETRABENAZINEACTIVE MOIETYZ9O08YRN8OXENAZINE (TETRABENAZINE) TABLET [LUNDBECK INC.]9
ferric oxide yellowINACTIVE INGREDIENTEX438O2MRTXENAZINE (TETRABENAZINE) TABLET [LUNDBECK INC.]9
lactoseINACTIVE INGREDIENTJ2B2A4N98GXENAZINE (TETRABENAZINE) TABLET [LUNDBECK INC.]9
magnesium stearateINACTIVE INGREDIENT70097M6I30XENAZINE (TETRABENAZINE) TABLET [LUNDBECK INC.]9
starch, cornINACTIVE INGREDIENTO8232NY3SJXENAZINE (TETRABENAZINE) TABLET [LUNDBECK INC.]9
talcINACTIVE INGREDIENT7SEV7J4R1UXENAZINE (TETRABENAZINE) TABLET [LUNDBECK INC.]9

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
67386-422XENAZINE (TETRABENAZINE) TABLET [LUNDBECK PHARMACEUTICALS LLC]21Current NDC, Legacy NDC, 1 package rows20220805_ac768bab-8afa-4446-bc7f-caeeffec0cda.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
tetrabenazineTETRABENAZINEOceanside Pharmaceuticals5867189c-17bd-4e70-a079-c4730f9950d12019-11-29Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021894
application number: NDA021894
XenazineTETRABENAZINELundbeck Pharmaceuticals LLCac768bab-8afa-4446-bc7f-caeeffec0cda2019-11-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021894
application number: NDA021894
ndc (package): 67386-422-01
ndc (product): 67386-422
ndc11 (package): 67386042201

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
805464tetrabenazine 12.5 MG Oral TabletPSNac768bab-8afa-4446-bc7f-caeeffec0cda21
199592tetrabenazine 25 MG Oral TabletPSNac768bab-8afa-4446-bc7f-caeeffec0cda21
805466Xenazine 12.5 MG Oral TabletPSNac768bab-8afa-4446-bc7f-caeeffec0cda21
805462Xenazine 25 MG Oral TabletPSNac768bab-8afa-4446-bc7f-caeeffec0cda21
805466tetrabenazine 12.5 MG Oral Tablet [Xenazine]SBDac768bab-8afa-4446-bc7f-caeeffec0cda21
805462tetrabenazine 25 MG Oral Tablet [Xenazine]SBDac768bab-8afa-4446-bc7f-caeeffec0cda21
805464tetrabenazine 12.5 MG Oral TabletSCDac768bab-8afa-4446-bc7f-caeeffec0cda21
199592tetrabenazine 25 MG Oral TabletSCDac768bab-8afa-4446-bc7f-caeeffec0cda21
805466Xenazine 12.5 MG Oral TabletSYac768bab-8afa-4446-bc7f-caeeffec0cda21
805462Xenazine 25 MG Oral TabletSYac768bab-8afa-4446-bc7f-caeeffec0cda21

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
67386-422-0167386042201112 TABLET in 1 BOTTLE (67386-422-01) 112 tablet2008-11-240000-00-00NoNoCurrent