Tizanidine

Product NDC
67877-614
11-digit product format
678770614
Labeler code
67877
Product ID
67877-614_e9f19258-b62c-471d-82c4-1e2bdc030833
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Tizanidine
Dosage form
TABLET
Route
ORAL
Labeler
Ascend Laboratories, LLC
Application
ANDA211798
Marketing category
ANDA
Marketing start
2019-01-27
Substance
TIZANIDINE HYDROCHLORIDE
Active strength
4 mg/1
Pharmacologic classes
Adrenergic alpha2-Agonists [MoA], Central alpha-2 Adrenergic Agonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211798-001TIZANIDINE HYDROCHLORIDETIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-25
A211798-002TIZANIDINE HYDROCHLORIDETIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A211798-001AB
A211798-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-25caaa826d4ba7…
2026-08-18 06:07:402026-07A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-25caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-255bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-25d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-25d06236e962d9…
2024-10-29 15:01 UTC2024-10A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-2579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-25301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-251e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-258072bd15b7f6…
2024-05-31 18:47 UTC2024-05A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-255c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-255d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-254b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-2574a2ff9319b5…
2019-12-13 00:20 UTC2019-12A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A211798-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASETABLET / ORALAB2019-01-25bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A211798-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASETABLET / ORALAB2019-01-25bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A211798-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A211798-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211798-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211798-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211798-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211798-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211798-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211798-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211798-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211798-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211798-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211798-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211798-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211798-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211798-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211798-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211798-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211798-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211798-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211798-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211798-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A211798-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211798-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211798-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211798-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211798-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211798-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211798-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211798-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A211798-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211798-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211798-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211798-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A211798-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211798-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A211798-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A211798-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A211798-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A211798-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A211798-002AB1bb7c543d1eb4…

Additional Listing Data#

Finished product
Yes
Brand name base
Tizanidine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TIZANIDINE HYDROCHLORIDE4 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
B53E3NMY5CInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
313412Internal RxNorm lookup
313413Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
72f25135-1333-4e52-83f5-7df7d90e68bbAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a0ff02d8-b711-423c-b7d1-ada00d81c743Product name120250805
9fd28b3a-d1bb-a2ce-ffa3-c3dd28536a01Product name820250313
b404127e-1c01-47bb-874e-db1e0b6bd9afProduct name420250313

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
67877-614-05Tizanidine500 in 1 BOTTLETABLET5007
67877-614-15Tizanidine150 in 1 BOTTLETABLET1507

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
67877-614-15EA - Each67877-61493aa994c-d137-4f31-9c0d-b2f7ff481ac612019-06-19

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
67877-614TIZANIDINE TABLET [ASCEND LABORATORIES, LLC]7Current NDC, Legacy NDC, 2 package rows20230314_72f25135-1333-4e52-83f5-7df7d90e68bb.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TizanidineTIZANIDINEAscend Laboratories, LLC72f25135-1333-4e52-83f5-7df7d90e68bb2023-03-13Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211798
application number: ANDA211798
ndc (product): 67877-614

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
313412tiZANidine HCl 2 MG Oral TabletPSN72f25135-1333-4e52-83f5-7df7d90e68bb7
313413tiZANidine HCl 4 MG Oral TabletPSN72f25135-1333-4e52-83f5-7df7d90e68bb7
313412tizanidine 2 MG Oral TabletSCD72f25135-1333-4e52-83f5-7df7d90e68bb7
313413tizanidine 4 MG Oral TabletSCD72f25135-1333-4e52-83f5-7df7d90e68bb7
313412tizanidine 2 MG (as tizanidine HCl 2.288 MG) Oral TabletSY72f25135-1333-4e52-83f5-7df7d90e68bb7
313413tizanidine 4 MG (as tizanidine HCl 4.576 MG) Oral TabletSY72f25135-1333-4e52-83f5-7df7d90e68bb7

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
67877-614-0567877061405500 TABLET in 1 BOTTLE (67877-614-05) 500 tablet2019-01-270000-00-00NoNoCurrent
67877-614-1567877061415150 TABLET in 1 BOTTLE (67877-614-15) 150 tablet2019-01-270000-00-00NoNoCurrent