Loperamide Hydrochloride

Product NDC
68071-2700
11-digit product format
680712700
Labeler code
68071
Product ID
68071-2700_17dec409-07e2-7ecc-e063-6294a90ac555
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Loperamide Hydrochloride
Dosage form
CAPSULE
Route
ORAL
Labeler
NuCare Pharmaceuticals,Inc.
Application
ANDA215579
Marketing category
ANDA
Marketing start
2021-12-01
Substance
LOPERAMIDE HYDROCHLORIDE
Active strength
2 mg/1
Pharmacologic classes
Opioid Agonist [EPC], Opioid Agonists [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A215579-001LOPERAMIDE HYDROCHLORIDELOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A215579-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-228072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-225c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-225d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-224b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-226a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-221c564ffb4f44…
2023-12-20 04:57 UTC2023-12A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-229b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-223f0d92c62455…
2023-05-13 08:27 UTC2023-05A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22053a50430f4f…
2023-01-26 05:58 UTC2023-01A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-223bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-223a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215579-001LOPERAMIDE HYDROCHLORIDE2MGCAPSULE / ORALAB2021-10-22a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A215579-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215579-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A215579-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215579-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215579-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215579-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215579-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215579-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215579-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215579-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215579-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215579-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215579-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215579-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A215579-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A215579-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A215579-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A215579-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A215579-001AB1782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215579-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A215579-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A215579-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A215579-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A215579-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A215579-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A215579-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A215579-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A215579-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A215579-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A215579-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A215579-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A215579-001AB1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215579-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Loperamide Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LOPERAMIDE HYDROCHLORIDE2 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
77TI35393CInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
978006Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
df4e7076-fd25-aeb8-e053-2995a90a2aa0Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
10f838ef-a72b-645d-80f8-e2255205c3b1Product name620240805

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
68071-2700-0Loperamide Hydrochloride10 in 1 BOTTLE, PLASTICCAPSULE103
68071-2700-1Loperamide Hydrochloride12 in 1 BOTTLE, PLASTICCAPSULE123
68071-2700-2Loperamide Hydrochloride20 in 1 BOTTLE, PLASTICCAPSULE203

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
68071-2700LOPERAMIDE HYDROCHLORIDE CAPSULE [NUCARE PHARMACEUTICALS,INC.]3Current NDC, Legacy NDC, 3 package rows20240508_df4e7076-fd25-aeb8-e053-2995a90a2aa0.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Loperamide HydrochlorideLOPERAMIDE HYDROCHLORIDEAvPAKf8992723-dd9a-bcf6-e053-6294a90aa65c2025-01-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215579
application number: ANDA215579
Loperamide HydrochlorideLOPERAMIDE HYDROCHLORIDENuCare Pharmaceuticals,Inc.df4e7076-fd25-aeb8-e053-2995a90a2aa02024-05-07Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215579
application number: ANDA215579
ndc (product): 68071-2700
Loperamide HydrochlorideLOPERAMIDE HYDROCHLORIDEBryant Ranch Prepack691c5dd6-b85d-482b-a8c1-8c4b48b48dc92024-04-03Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215579
application number: ANDA215579
Loperamide HydrochlorideLOPERAMIDE HYDROCHLORIDEBionpharma Inc.6e60cb25-6af9-4f17-b740-a5e7b5bb2a092023-12-27Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215579
application number: ANDA215579

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
978006loperamide HCl 2 MG Oral CapsulePSNdf4e7076-fd25-aeb8-e053-2995a90a2aa03
978006loperamide hydrochloride 2 MG Oral CapsuleSCDdf4e7076-fd25-aeb8-e053-2995a90a2aa03

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
68071-2700-06807127000010 CAPSULE in 1 BOTTLE, PLASTIC (68071-2700-0) 10 capsule2022-05-18NoNoCurrent
68071-2700-16807127000112 CAPSULE in 1 BOTTLE, PLASTIC (68071-2700-1) 12 capsule2022-05-180000-00-00NoNoCurrent
68071-2700-26807127000220 CAPSULE in 1 BOTTLE, PLASTIC (68071-2700-2) 20 capsule2022-05-180000-00-00NoNoCurrent