tramadol hydrochloride

Product NDC
68134-402
11-digit product format
681340402
Labeler code
68134
Product ID
68134-402_dca135cf-1ae0-a00e-e053-2995a90a1203
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
tramadol hydrochloride
Dosage form
SOLUTION
Route
ORAL
Labeler
Palmetto Pharmaceuticals, Inc.
Application
NDA214044
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
2020-09-11
Marketing end
0000-00-00
Substance
TRAMADOL HYDROCHLORIDE
Active strength
5 mg/mL
Pharmacologic classes
Full Opioid Agonists [MoA], Opioid Agonist [EPC]
DEA schedule
CIV
NDC exclude flag
No
Listing certified through
2023-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct68134-402IInactivated by FDA2026-08-07
excluded packagepackage68134-40268134-402-40IInactivated by FDA2026-08-07

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N214044-001QDOLOTRAMADOL HYDROCHLORIDE5MG/MLSOLUTION / ORALRLD2020-09-01

Orange Book patents#

Current patent rows page 1 of 1 · 2 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N214044-001111034522040-09-01U-3197Drug product2021-09-02
N214044-001117521032040-09-01U-3197Drug product2023-09-14

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N214044-001QDOLO5MG/MLSOLUTION / ORALRLD2020-09-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214044-001QDOLO5MG/MLSOLUTION / ORALRLD2020-09-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08N214044-001QDOLO5MG/MLSOLUTION / ORALRLD2020-09-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214044-001QDOLO5MG/MLSOLUTION / ORALRLD2020-09-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214044-001QDOLO5MG/MLSOLUTION / ORALRLD2020-09-01b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214044-001QDOLO5MG/MLSOLUTION / ORALRLD2020-09-0103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214044-001QDOLO5MG/MLSOLUTION / ORALRLD2020-09-012680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-015bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214044-001QDOLO5MG/MLSOLUTION / ORALRLD2020-09-01d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-0179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-011e350fbaab3a…
2024-05-31 18:47 UTC2024-05N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-018072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-015c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-015d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-014b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-0187673890dc5c…
2021-03-12 10:30 UTC2021-03N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-015aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-018869cabd3fbd…
2020-11-12 02:37 UTC2020-11N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-016a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-011c564ffb4f44…
2023-12-20 04:57 UTC2023-12N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-019b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-013f0d92c62455…
2023-05-13 08:27 UTC2023-05N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01053a50430f4f…
2023-01-26 05:58 UTC2023-01N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-013bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-013a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N214044-001QDOLO5MG/MLSOLUTION / ORALRLD, RS2020-09-01cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N214044-001QDOLO5MG/MLSOLUTION / ORALRLD2020-09-01a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 2 · 53 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N214044-001111034522040-09-01U-3197Drug product2021-09-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214044-001117521032040-09-01U-3197Drug product2023-09-14011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214044-001111034522040-09-01U-3197Drug product2021-09-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214044-001117521032040-09-01U-3197Drug product2023-09-1431067a03dcf5…
2025-08-23 18:47 UTC2025-08N214044-001111034522040-09-01U-3197Drug product2021-09-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214044-001117521032040-09-01U-3197Drug product2023-09-146a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214044-001111034522040-09-01U-3197Drug product2021-09-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214044-001117521032040-09-01U-3197Drug product2023-09-14fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214044-001111034522040-09-01U-3197Drug product2021-09-02b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214044-001117521032040-09-01U-3197Drug product2023-09-14b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214044-001111034522040-09-01U-3197Drug product2021-09-0203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214044-001117521032040-09-01U-3197Drug product2023-09-1403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214044-001111034522040-09-01U-3197Drug product2021-09-022680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214044-001117521032040-09-01U-3197Drug product2023-09-142680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214044-001111034522040-09-01U-3197Drug product2021-09-025bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214044-001117521032040-09-01U-3197Drug product2023-09-145bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214044-001111034522040-09-01U-3197Drug product2021-09-02d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214044-001117521032040-09-01U-3197Drug product2023-09-14d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N214044-001111034522040-09-01U-3197Drug product2021-09-02d06236e962d9…
2024-10-29 15:01 UTC2024-10N214044-001117521032040-09-01U-3197Drug product2023-09-14d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N214044-001111034522040-09-01U-3197Drug product2021-09-0279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N214044-001117521032040-09-01U-3197Drug product2023-09-1479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N214044-001111034522040-09-01U-3197Drug product2021-09-02301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N214044-001117521032040-09-01U-3197Drug product2023-09-14301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N214044-001111034522040-09-01U-3197Drug product2021-09-021e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N214044-001117521032040-09-01U-3197Drug product2023-09-141e350fbaab3a…
2024-05-31 18:47 UTC2024-05N214044-001111034522040-09-01U-3197Drug product2021-09-028072bd15b7f6…
2024-05-31 18:47 UTC2024-05N214044-001117521032040-09-01U-3197Drug product2023-09-148072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N214044-001111034522040-09-01U-3197Drug product2021-09-025c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N214044-001111034522040-09-01U-3197Drug product2021-09-025d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N214044-001111034522040-09-01U-3197Drug product2021-09-024b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N214044-001111034522040-09-01U-3197Drug product2021-09-02bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N214044-001111034522040-09-01U-3197Drug product2021-09-02782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N214044-001111034522040-09-01U-3197Drug product2021-09-026a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N214044-001117521032040-09-01U-3197Drug product2023-09-146a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N214044-001111034522040-09-01U-3197Drug product2021-09-021c564ffb4f44…
2024-02-18 07:12 UTC2024-02N214044-001117521032040-09-01U-3197Drug product2023-09-141c564ffb4f44…
2023-12-20 04:57 UTC2023-12N214044-001111034522040-09-01U-3197Drug product2021-09-02ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12N214044-001117521032040-09-01U-3197Drug product2023-09-14ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N214044-001111034522040-09-01U-3197Drug product2021-09-02a72a2bbeb626…

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
43d017e1-6ae6-7555-71d1-c249236d6f26Product name420251117
bff1fbab-f4cc-4993-b7de-2b555ee5eb73Product name120220509
c6f86816-7da6-43ea-8c25-ac9758311cc5Product name120220118
c563c906-2606-457c-bb1b-5a623daed55bProduct name120210511
43a9f8f9-34aa-8ae8-719e-5489454f7720Product name520200123
abd2f6f2-3fa7-4571-af8a-d67f89bdcb75Product name120190927
252e11b6-1a9a-4283-a242-df2c129c496dProduct name320170717
377068df-225f-7318-a910-a1987cdfa361Product name320170608
9457302e-0ca3-d9ff-0863-1b24b6107218Product name120140508
d5c49867-1fe9-7a44-3319-814417011d51Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
68134-402-05tramadol hydrochloride5 mL in 1 CUP, UNIT-DOSESOLUTION55
68134-402-40tramadol hydrochloride10 in 1 TRAYSOLUTION105
68134-402-40tramadol hydrochloride4 in 1 CASESOLUTION45

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
68134-402-05ML - Milliliter68134-4023c9c3723-8a63-4e8e-a882-85bbdafb7a0212022-05-04
68134-402-40ML - Milliliter68134-40221c3ec0a-a76b-4527-b33f-18051458b95812022-05-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
68134-402TRAMADOL HYDROCHLORIDE SOLUTION [PALMETTO PHARMACEUTICALS, INC.]5Legacy NDC, 3 package rows20241210_2804c640-9d47-4b40-b58b-da321b79cf39.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Tramadol HydrochlorideTRAMADOL HYDROCHLORIDETruPharma, LLCaea56ff9-94ac-47a8-8f15-8790d538973b2023-01-25Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 214044
application number: NDA214044

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2395808traMADol hydrochloride 5 MG in 1 mL Oral SolutionPSN2804c640-9d47-4b40-b58b-da321b79cf395
2395808tramadol hydrochloride 5 MG/ML Oral SolutionSCD2804c640-9d47-4b40-b58b-da321b79cf395
2395808tramadol hydrochloride 5 MG per 1 ML Oral SolutionSY2804c640-9d47-4b40-b58b-da321b79cf395

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
68134-402-05681340402055 mL in 1 CUP, UNIT-DOSE5 mlHistorical
68134-402-40681340402404 TRAY in 1 CASE (68134-402-40) > 10 CUP, UNIT-DOSE in 1 TRAY > 5 mL in 1 CUP, UNIT-DOSE (68134-402-05) 4 tray2021-09-160000-00-00NoNoCurrent