Bumetanide

Product NDC
68462-470
11-digit product format
684620470
Labeler code
68462
Product ID
68462-470_f211e18e-2cd7-4316-8edc-089ed734ccb8
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Bumetanide
Dosage form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Labeler
GLENMARK PHARMACEUTICALS INC., USA
Application
ANDA216434
Marketing category
ANDA
Marketing start
2023-01-01
Substance
BUMETANIDE
Active strength
.25 mg/mL
Pharmacologic classes
Increased Diuresis at Loop of Henle [PE], Loop Diuretic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216434-001BUMETANIDEBUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A216434-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-265c6f7cd8ea54…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-266a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-261c564ffb4f44…
2023-12-20 04:57 UTC2023-12A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-269b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-263f0d92c62455…
2023-05-13 08:27 UTC2023-05A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26053a50430f4f…
2023-01-26 05:58 UTC2023-01A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-263bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-263a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216434-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-05-26a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A216434-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216434-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A216434-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216434-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216434-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216434-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216434-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216434-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216434-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216434-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216434-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216434-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A216434-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A216434-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A216434-001AP15c6f7cd8ea54…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A216434-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A216434-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A216434-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A216434-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A216434-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A216434-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A216434-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A216434-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A216434-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A216434-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A216434-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A216434-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A216434-001AP1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216434-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Bumetanide
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BUMETANIDE.25 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
0Y2S3XUQ5HInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
282486Internal RxNorm lookup
1727569Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
680563fe-5d3a-49bc-86a5-740bda2acebeAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1d3f2f0a-cce7-32fe-77bf-6ee61839e736Product name920260113
601d9750-f415-d9d9-619c-0a87b4d3f237Product name320250331
1d3f2f0a-cce7-32fe-77bf-6ee61839e736Product name220171211

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
68462-470-40Bumetanide10 mL in 1 VIAL, MULTI-DOSEINJECTION102
68462-470-54Bumetanide10 in 1 CARTONINJECTION102

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
68462-470-40ML - Milliliter68462-4708f2e812f-1839-493d-86c2-77d1126f5d0d12023-02-06
68462-470-54ML - Milliliter68462-470ee7573af-6365-4c71-99f8-e5e014b12be612023-02-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
68462-470BUMETANIDE INJECTION [GLENMARK PHARMACEUTICALS INC., USA]1Current NDC, Legacy NDC, 2 package rows20230107_680563fe-5d3a-49bc-86a5-740bda2acebe.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
BumetanideBUMETANIDEGLENMARK PHARMACEUTICALS INC., USA680563fe-5d3a-49bc-86a5-740bda2acebe2023-01-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216434
application number: ANDA216434
ndc (product): 68462-470
BumetanideBUMETANIDEFresenius Kabi USA, LLCa007f3aa-3977-4be3-a9a2-db3d458bca582022-09-19Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216434
application number: ANDA216434
BumetanideBUMETANIDEGland Pharma Limited4d1ed6b2-c410-4f52-9b8a-aa256c37089e2022-06-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216434
application number: ANDA216434

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
282486bumetanide 0.25 MG/ML Injectable SolutionPSN680563fe-5d3a-49bc-86a5-740bda2acebe2
1727569bumetanide 1 MG in 4 ML InjectionPSN680563fe-5d3a-49bc-86a5-740bda2acebe2
17275694 ML bumetanide 0.25 MG/ML InjectionSCD680563fe-5d3a-49bc-86a5-740bda2acebe2
282486bumetanide 0.25 MG/ML Injectable SolutionSCD680563fe-5d3a-49bc-86a5-740bda2acebe2
1727569bumetanide 1 MG per 4 ML InjectionSY680563fe-5d3a-49bc-86a5-740bda2acebe2

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
68462-470-406846204704010 mL in 1 VIAL, MULTI-DOSE10 mlHistorical
68462-470-546846204705410 VIAL, MULTI-DOSE in 1 CARTON (68462-470-54) / 10 mL in 1 VIAL, MULTI-DOSE (68462-470-40) 2023-01-010000-00-00NoNoCurrent