ethacrynic acid

Product NDC
68682-011
11-digit product format
686820011
Labeler code
68682
Product ID
68682-011_4c621e16-3dbb-4774-935e-69270e52fe8e
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ethacrynic acid
Dosage form
TABLET
Route
ORAL
Labeler
Oceanside Pharmaceuticals
Application
NDA016092
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
1967-01-10
Substance
ETHACRYNIC ACID
Active strength
25 mg/1
Pharmacologic classes
Increased Diuresis at Loop of Henle [PE], Loop Diuretic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N016092-001EDECRINETHACRYNIC ACID25MGTABLET / ORALABRLD, RS, Approved before 1982
N016092-002EDECRINETHACRYNIC ACID50MGTABLET / ORALApproved before 1982

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N016092-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 1982caaa826d4ba7…
2026-08-18 06:07:402026-07N016092-002EDECRIN50MGTABLET / ORALApproved before 1982caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 1982011fe1cb6892…
2026-02-19 14:30 UTC2026-02N016092-002EDECRIN50MGTABLET / ORALApproved before 1982011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 198231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N016092-002EDECRIN50MGTABLET / ORALApproved before 198231067a03dcf5…
2025-08-23 18:47 UTC2025-08N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 19826a471c1ec25d…
2025-08-23 18:47 UTC2025-08N016092-002EDECRIN50MGTABLET / ORALApproved before 19826a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 1982fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N016092-002EDECRIN50MGTABLET / ORALApproved before 1982fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 1982b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N016092-002EDECRIN50MGTABLET / ORALApproved before 1982b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 198203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N016092-002EDECRIN50MGTABLET / ORALApproved before 198203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 19822680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N016092-002EDECRIN50MGTABLET / ORALApproved before 19822680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 19825bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N016092-002EDECRIN50MGTABLET / ORALApproved before 19825bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 1982d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N016092-002EDECRIN50MGTABLET / ORALApproved before 1982d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 1982d06236e962d9…
2024-10-29 15:01 UTC2024-10N016092-002EDECRIN50MGTABLET / ORALApproved before 1982d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 198279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N016092-002EDECRIN50MGTABLET / ORALApproved before 198279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 1982301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N016092-002EDECRIN50MGTABLET / ORALApproved before 1982301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 19821e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N016092-002EDECRIN50MGTABLET / ORALApproved before 19821e350fbaab3a…
2024-05-31 18:47 UTC2024-05N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 19828072bd15b7f6…
2024-05-31 18:47 UTC2024-05N016092-002EDECRIN50MGTABLET / ORALApproved before 19828072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 19825c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N016092-002EDECRIN50MGTABLET / ORALApproved before 19825c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 19825d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N016092-002EDECRIN50MGTABLET / ORALApproved before 19825d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 19824b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N016092-002EDECRIN50MGTABLET / ORALApproved before 19824b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 198274a2ff9319b5…
2019-12-13 00:20 UTC2019-12N016092-002EDECRIN50MGTABLET / ORALApproved before 198274a2ff9319b5…
2022-03-09 01:35 UTC2022-03N016092-001EDECRIN25MGTABLET / ORALABRLD, RS, Approved before 1982bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N016092-002EDECRIN50MGTABLET / ORALApproved before 1982bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N016092-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N016092-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N016092-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N016092-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N016092-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N016092-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N016092-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N016092-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N016092-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N016092-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N016092-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N016092-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N016092-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N016092-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N016092-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N016092-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N016092-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N016092-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N016092-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N016092-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N016092-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N016092-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03N016092-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N016092-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N016092-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N016092-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09N016092-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07N016092-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N016092-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N016092-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N016092-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N016092-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N016092-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N016092-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N016092-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05N016092-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01N016092-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N016092-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N016092-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N016092-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
ethacrynic acid
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ETHACRYNIC ACID25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
M5DP350VZVInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
617325Internal RxNorm lookup
1251903Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
f127598f-e6b3-4c35-800f-76e4217595aeAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
93aead9c-5c26-5d19-73e9-d6c55a939061Product name920210525
01098bd8-4859-4cc2-9426-3489bf88d451Product name420201216

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
68682-011-10ethacrynic acid100 in 1 BOTTLETABLET10014

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
68682-011-10EA - Each68682-011cb874015-077f-4218-ab5d-0e9f06ac145a12016-10-06

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ETHACRYNATE SODIUMACTIVE INGREDIENTK41MYV7MPMETHACRYNIC SODIUM POWDER, FOR SOLUTION [OCEANSIDE PHARMACEUTICALS]1
ETHACRYNIC ACIDACTIVE MOIETYM5DP350VZVETHACRYNIC SODIUM POWDER, FOR SOLUTION [OCEANSIDE PHARMACEUTICALS]1
MANNITOLINACTIVE INGREDIENT3OWL53L36AETHACRYNIC SODIUM POWDER, FOR SOLUTION [OCEANSIDE PHARMACEUTICALS]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
68682-011ETHACRYNIC SODIUM POWDER, FOR SOLUTION ETHACRYNIC ACID TABLET [OCEANSIDE PHARMACEUTICALS]14Current NDC, Legacy NDC, 1 package rows20240802_f127598f-e6b3-4c35-800f-76e4217595ae.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ethacrynic acidETHACRYNIC ACIDOceanside Pharmaceuticalsf127598f-e6b3-4c35-800f-76e4217595ae2023-08-31Warnings, Adverse reactionsExact identifier
application applno (NDA): 016092
application number: NDA016092
ndc (product): 68682-011
EDECRINETHACRYNIC ACIDBausch Health US, LLC1efe378e-fee1-4ae9-8ea5-0fe2265fe2d82020-08-31Warnings, Adverse reactionsExact identifier
application applno (NDA): 016092
application number: NDA016092

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
617325ethacrynate sodium 50 MG InjectionPSNf127598f-e6b3-4c35-800f-76e4217595ae14
1251903ethacrynic acid 25 MG Oral TabletPSNf127598f-e6b3-4c35-800f-76e4217595ae14
617325ethacrynate sodium 50 MG InjectionSCDf127598f-e6b3-4c35-800f-76e4217595ae14
1251903ethacrynic acid 25 MG Oral TabletSCDf127598f-e6b3-4c35-800f-76e4217595ae14
617325ethacrynate sodium 50 MG (equivalent to ethacrynic acid 50 MG) InjectionSYf127598f-e6b3-4c35-800f-76e4217595ae14

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
68682-011-1068682001110100 TABLET in 1 BOTTLE (68682-011-10) 100 tablet1967-01-100000-00-00NoNoCurrent