Isotretinoin

Product NDC
69238-1259
11-digit product format
692381259
Labeler code
69238
Product ID
69238-1259_831e90e7-4cd9-44e1-8f94-b136bcba2b5b
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Isotretinoin
Dosage form
CAPSULE
Route
ORAL
Labeler
Amneal Pharmaceuticals NY LLC
Application
ANDA216097
Marketing category
ANDA
Marketing start
2025-10-10
Substance
ISOTRETINOIN
Active strength
40 mg/1
Pharmacologic classes
Retinoid [EPC], Retinoids [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 6 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216097-001ISOTRETINOINISOTRETINOIN10MGCAPSULE / ORAL2025-10-07
A216097-002ISOTRETINOINISOTRETINOIN20MGCAPSULE / ORAL2025-10-07
A216097-003ISOTRETINOINISOTRETINOIN25MGCAPSULE / ORAL2025-10-07
A216097-004ISOTRETINOINISOTRETINOIN30MGCAPSULE / ORAL2025-10-07
A216097-005ISOTRETINOINISOTRETINOIN35MGCAPSULE / ORAL2025-10-07
A216097-006ISOTRETINOINISOTRETINOIN40MGCAPSULE / ORAL2025-10-07

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A216097-001ISOTRETINOIN10MGCAPSULE / ORALAB22025-10-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-002ISOTRETINOIN20MGCAPSULE / ORALAB22025-10-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-003ISOTRETINOIN25MGCAPSULE / ORALAB22025-10-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-004ISOTRETINOIN30MGCAPSULE / ORALAB22025-10-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-005ISOTRETINOIN35MGCAPSULE / ORALAB22025-10-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-006ISOTRETINOIN40MGCAPSULE / ORALAB22025-10-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-001ISOTRETINOIN10MGCAPSULE / ORALAB22025-10-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-002ISOTRETINOIN20MGCAPSULE / ORALAB22025-10-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-003ISOTRETINOIN25MGCAPSULE / ORALAB22025-10-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-004ISOTRETINOIN30MGCAPSULE / ORALAB22025-10-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-005ISOTRETINOIN35MGCAPSULE / ORALAB22025-10-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-006ISOTRETINOIN40MGCAPSULE / ORALAB22025-10-0731067a03dcf5…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216097-001ISOTRETINOIN10MGCAPSULE / ORAL2025-10-07a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216097-002ISOTRETINOIN20MGCAPSULE / ORAL2025-10-07a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216097-003ISOTRETINOIN25MGCAPSULE / ORAL2025-10-07a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216097-004ISOTRETINOIN30MGCAPSULE / ORAL2025-10-07a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216097-005ISOTRETINOIN35MGCAPSULE / ORAL2025-10-07a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216097-006ISOTRETINOIN40MGCAPSULE / ORAL2025-10-07a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A216097-001AB21011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-002AB21011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-003AB21011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-004AB21011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-005AB21011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216097-006AB21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-001AB2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-002AB2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-003AB2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-004AB2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-005AB2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216097-006AB2131067a03dcf5…

Additional Listing Data#

Finished product
Yes
Brand name base
Isotretinoin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ISOTRETINOIN40 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
EH28UP18IFInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 6 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197843Internal RxNorm lookup
197844Internal RxNorm lookup
197845Internal RxNorm lookup
403930Internal RxNorm lookup
1547561Internal RxNorm lookup
1547565Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9f1c8971-c6dc-4708-848b-5cee50b6c32aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
8300c0f6-79a4-735b-88ec-d781bfffdb10Product name520260305
644afe93-ba9b-4043-8e40-a9fe9af2d5d7Product name220250616
baf7f49c-75b6-496b-a00e-8e766a8e4f03Product name120210127
e5fedfa5-6b96-4769-872b-95d1e7f3a85aProduct name120200415
ebc62596-fc97-4d03-9483-7ba095d25db7Product name120151210
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
69238-1259-3Isotretinoin3 in 1 BOXCAPSULE39
69238-1259-4Isotretinoin10 in 1 BLISTER PACKCAPSULE109

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
IsotretinoinISOTRETINOINAmneal Pharmaceuticals NY LLC9f1c8971-c6dc-4708-848b-5cee50b6c32a2023-08-24Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216097
application number: ANDA216097
ndc (product): 69238-1259

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197843ISOtretinoin 10 MG Oral CapsulePSN9f1c8971-c6dc-4708-848b-5cee50b6c32a9
197844ISOtretinoin 20 MG Oral CapsulePSN9f1c8971-c6dc-4708-848b-5cee50b6c32a9
1547561ISOtretinoin 25 MG Oral CapsulePSN9f1c8971-c6dc-4708-848b-5cee50b6c32a9
403930ISOtretinoin 30 MG Oral CapsulePSN9f1c8971-c6dc-4708-848b-5cee50b6c32a9
1547565ISOtretinoin 35 MG Oral CapsulePSN9f1c8971-c6dc-4708-848b-5cee50b6c32a9
197845ISOtretinoin 40 MG Oral CapsulePSN9f1c8971-c6dc-4708-848b-5cee50b6c32a9
197843isotretinoin 10 MG Oral CapsuleSCD9f1c8971-c6dc-4708-848b-5cee50b6c32a9
197844isotretinoin 20 MG Oral CapsuleSCD9f1c8971-c6dc-4708-848b-5cee50b6c32a9
1547561isotretinoin 25 MG Oral CapsuleSCD9f1c8971-c6dc-4708-848b-5cee50b6c32a9
403930isotretinoin 30 MG Oral CapsuleSCD9f1c8971-c6dc-4708-848b-5cee50b6c32a9
1547565isotretinoin 35 MG Oral CapsuleSCD9f1c8971-c6dc-4708-848b-5cee50b6c32a9
197845isotretinoin 40 MG Oral CapsuleSCD9f1c8971-c6dc-4708-848b-5cee50b6c32a9

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
69238-1259-3692381259033 BLISTER PACK in 1 BOX (69238-1259-3) / 10 CAPSULE in 1 BLISTER PACK (69238-1259-4) 3 blister pack2025-10-10NoNoCurrent
69238-1259-46923812590410 in 1 BLISTER PACKHistorical