Head and Shoulders Conditioner

Product NDC: 69423-103
Requested package NDC: 69423-103-59
11-digit product format: 694230103
Labeler code: 69423
Product ID: 69423-103_463f04e3-2618-2343-e063-6394a90a6ae4
Type: HUMAN OTC DRUG
Nonproprietary name: Pyrithione Zinc
Dosage form: LOTION
Route: TOPICAL
Labeler: The Procter & Gamble Manufacturing Company
Application: M032
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2016-11-10
Substance: PYRITHIONE ZINC
Active strength: .5 g/100mL
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Head and Shoulders Conditioner
Brand name suffix: Smooth and Silky
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
PYRITHIONE ZINC	.5 g/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
R953O2RHZ5	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1043014	Internal RxNorm lookup
1044465	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
41709710-539c-3119-e054-00144ff88e88	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
362d7abb-94e6-4c60-9a58-266894157713	Product name	1	20231023
6bd95106-a412-1dad-b9cc-4cb74bfb27ce	Product name	2	20230315
c6f86816-7da6-43ea-8c25-ac9758311cc5	Product name	1	20220118
f1e0dc7e-7d61-4625-b6d9-4894927679d7	Product name	2	20211025
e4870509-7e28-6f92-f0be-dd3dd889a9cf	Product name	5	20200810
6e9d4a47-c464-b93e-aebc-ad7bffc9c4cd	Product name	2	20190619
444b3e50-f226-46ef-bfca-2e7035d140cd	Product name	1	20190611
816b97af-edc5-4060-aff1-b814bdbcad50	Product name	1	20190415
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
252e11b6-1a9a-4283-a242-df2c129c496d	Product name	3	20170717
419aab54-5d5a-4146-9453-026d4a9991be	Product name	2	20170525
d5e51f11-ad28-caa4-4b49-4143974782ad	Product name	1	20150831
290f523a-f9db-9774-b5a9-e1f908ac1782	Product name	1	20150828
0ca1d589-929b-4b33-bc5b-1d84abdafa6a	Product name	1	20150324
fc363c46-397b-4476-ac0f-70e43e8e4592	Product name	1	20150324
89dac932-b90a-4410-9ab1-84c53e57de25	Product name	1	20150316
5668b646-cd56-c3c7-bdea-3f6b1a8840db	Product name	1	20140508
684ea482-2e8b-14af-5664-b98f1e402036	Product name	1	20140508
810ab97e-f109-f41c-7c83-6a652a9cbf43	Product name	1	20140508
87711080-88eb-65c5-b2dd-bf99e700a372	Product name	1	20140508
8dbefedf-0a0d-a224-5a3c-66dc9e11c2dd	Product name	1	20140508
9869efd7-d6dd-0665-5b67-53adbe6ef15e	Product name	1	20140508
b060cc1a-fe47-856b-0b77-4448b5963de8	Product name	1	20140508
c6b65c52-69c7-df49-550a-a50c137f6218	Product name	1	20140508
ec2149b3-5c6d-5344-f757-c86411073075	Product name	1	20140508
ed912195-5da0-0f2f-6f4b-3ef17710cbe3	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
69423-103-10	Head and Shoulders ConditionerSmooth and Silky	10 mL in 1 POUCH	LOTION	10		12
69423-103-25	Head and Shoulders ConditionerSmooth and Silky	250 mL in 1 BOTTLE, PLASTIC	LOTION	250		12
69423-103-31	Head and Shoulders ConditionerSmooth and Silky	315 mL in 1 TUBE	LOTION	315		12
69423-103-38	Head and Shoulders ConditionerSmooth and Silky	380 mL in 1 BOTTLE, PLASTIC	LOTION	380		12
69423-103-40	Head and Shoulders ConditionerSmooth and Silky	400 mL in 1 BOTTLE, PLASTIC	LOTION	400		12
69423-103-59	Head and Shoulders ConditionerSmooth and Silky	592 mL in 1 BOTTLE, PLASTIC	LOTION	592		12
69423-103-61	Head and Shoulders ConditionerSmooth and Silky	610 mL in 1 BOTTLE, PLASTIC	LOTION	610		12
69423-103-65	Head and Shoulders ConditionerSmooth and Silky	650 mL in 1 BOTTLE, PLASTIC	LOTION	650		12
69423-103-68	Head and Shoulders ConditionerSmooth and Silky	680 mL in 1 BOTTLE, PLASTIC	LOTION	680		12
69423-103-90	Head and Shoulders ConditionerSmooth and Silky	90 mL in 1 BOTTLE, PLASTIC	LOTION	90		12
69423-103-10	Head and Shoulders Dual SachetsSmooth and Silky	10 mL in 1 POUCH	LOTION	10 mL	0.5 g in 100mL	2
69423-103-31	Head and Shoulders Dual PackSmooth and Silky	315 mL in 1 TUBE	LOTION	315 mL	0.5 g in 100mL	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
69423-103	HEAD AND SHOULDERS CONDITIONER SMOOTH AND SILKY (PYRITHIONE ZINC) LOTION [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	11	Current NDC, Legacy NDC, 10 package rows	20241023_41709710-539c-3119-e054-00144ff88e88.zip
69423-103	HEAD AND SHOULDERS DUAL PACK SMOOTH AND SILKY (PYRITHIONE ZINC) KIT [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	4	Current NDC, Legacy NDC	20250524_a9500735-c938-0ad5-e053-2995a90afa50.zip
69423-103	HEAD AND SHOULDERS DUAL SACHETS SMOOTH AND SILKY (PYRITHIONE ZINC) KIT [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	2	Current NDC, Legacy NDC	20200110_7a2c32f7-182b-8959-e053-2991aa0a3a12.zip
69423-103	HEAD AND SHOULDERS DUAL PACK SMOOTH AND SILKY (PYRITHIONE ZINC) KIT [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	1	Current NDC, Legacy NDC	20240601_19ad72ea-9a4b-0a35-e063-6394a90a9131.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 7 of 31 · 615 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Head and Shoulders Itchy Scalp	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	54df1acc-4265-494c-879e-c690184d7ae2	2026-03-13	Warnings	Exact identifier application number: M032
2 in 1 Dandruff	PYRITHIONE ZINC	H E B	a58b9119-2adb-459f-86f4-95df28a430c5	2026-03-13	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp Care	PYRITHIONE ZINC	Better Living Brands, LLC	f90d1fb2-4bd7-4d70-81b4-4541f4e3a3d6	2026-03-13	Warnings, Adverse reactions	Exact identifier application number: M032
Head and Shoulders Smooth and Silky Conditioner	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	4cec08cb-aba5-41ce-e063-6294a90adfdf	2026-03-13	Warnings	Exact identifier application number: M032
OLIVITA Minoxidil	MINOXIDIL	Shenzhen Xinxin Yunhai Technology Co., Ltd.	4cf37b0b-bbb8-1d9c-e063-6294a90af818	2026-03-13	Warnings	Exact identifier application number: M032
Dandruff	PYRITHIONE ZINC	Nice-Pak Products, LLC	3c55b70f-7627-8667-e063-6394a90a5cf8	2026-03-12	Warnings, Adverse reactions	Exact identifier application number: M032
Head and Shoulders 2in1 Classic Clean	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	65a4082f-227b-49bf-b88c-b1c651ed13a0	2026-03-12	Warnings	Exact identifier application number: M032
Head and Shoulders Green Apple 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	c036c9a6-6507-4037-b97b-1b015dd950c1	2026-03-12	Warnings	Exact identifier application number: M032
Anti-Fungal	ANTI-FUNGAL SHAMPOO	Shenzhen Mengyue Technology Co., Ltd.	4ca9a661-fa39-ab7f-e063-6294a90aed14	2026-03-10	Warnings	Exact identifier application number: M032
iBeaLee 5% Minoxidil Hair Regrowth Treatment	5% MINOXIDIL	Shenzhen Earth Surface Trading Co., Ltd.	4cb728d0-6abe-6645-e063-6394a90acb4c	2026-03-10	Warnings	Exact identifier application number: M032
DHS Tar	COAL TAR	Person and Covey	4c5f7278-c53a-cef6-e063-6394a90a0008	2026-03-09	Warnings	Exact identifier application number: M032
DHS ZINC	PYRITHIONE ZINC	Person and Covey	4c98c0af-c3d0-211e-e063-6294a90a8e12	2026-03-09	Warnings	Exact identifier application number: M032
DHS SAL	SALICYLIC ACID	Person and Covey	4c9b75b5-9c7d-c4a8-e063-6394a90a4a6b	2026-03-09	Warnings	Exact identifier application number: M032
DHS BODY WASH	ZINC PYRITHIONE WASH	Person and Covey	4c9d5b33-9a1e-9db1-e063-6294a90adbae	2026-03-09	Warnings	Exact identifier application number: M032
Biotin	BIOTIN	Shenzhen yuehaotong Technology Co.,Ltd	4c6ec616-a84e-6e1a-e063-6294a90a2aae	2026-03-07	Warnings	Exact identifier application number: M032
2 in 1 Dandruff	PYRITHIONE ZINC	Old East Main Co.	5368b466-a804-471c-8287-0dd120c0d509	2026-03-03	Warnings, Adverse reactions	Exact identifier application number: M032
Dandruff	PYRITHIONE ZINC	Amazon.com Services LLC	c187bb79-8190-4a3d-a966-af74198ee546	2026-03-03	Warnings, Adverse reactions	Exact identifier application number: M032
Simply Clean Dandruff	PYRITHIONE ZINC	Old East Main Co.	643f571a-cf08-4f1f-9ad4-2bc68730ff57	2026-03-02	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp Care	PYRITHIONE ZINC	Old East Main Co.	3c433aa9-9451-4820-8b58-632cf6d0c92a	2026-03-02	Warnings, Adverse reactions	Exact identifier application number: M032
2 in 1 Dandruff	PYRITHIONE ZINC	Old East Main Co.	3afc97ff-6a83-40af-9a61-26f00cfe4fa8	2026-03-02	Warnings, Adverse reactions	Exact identifier application number: M032

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R953O2RHZ5	PYRITHIONE ZINC	13463-41-7	PYRITHIONE ZINC

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1044465	head & shoulders 0.5 % Medicated Shampoo	PSN	41709710-539c-3119-e054-00144ff88e88	12
1043014	zinc pyrithione 0.5 % Medicated Conditioner	PSN	41709710-539c-3119-e054-00144ff88e88	12
1044465	zinc pyrithione 5 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	41709710-539c-3119-e054-00144ff88e88	12
1043014	zinc pyrithione 5 MG/ML Medicated Shampoo	SCD	41709710-539c-3119-e054-00144ff88e88	12
1044465	Head & Shoulders 0.5 % Conditioner	SY	41709710-539c-3119-e054-00144ff88e88	12
1044465	Head & Shoulders 5 MG/ML Medicated Shampoo	SY	41709710-539c-3119-e054-00144ff88e88	12
1043014	zinc pyrithione 0.5 % Medicated Shampoo	SY	41709710-539c-3119-e054-00144ff88e88	12
1441654	{1 (10 ML) (zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]) / 1 (10 ML) (zinc pyrithione 5 MG/ML Medicated Shampoo [Head & Shoulders]) } Pack [Head & Shoulders Dual Sachets]	BPCK	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1441653	{1 (10 ML) (zinc pyrithione 10 MG/ML Medicated Shampoo) / 1 (10 ML) (zinc pyrithione 5 MG/ML Medicated Shampoo) } Pack	GPCK	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1044465	head & shoulders 0.5 % Medicated Shampoo	PSN	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1044465	head & shoulders 0.5 % Medicated Shampoo	PSN	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1043244	head & shoulders 1 % Medicated Shampoo	PSN	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1043244	head & shoulders 1 % Medicated Shampoo	PSN	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1441654	Head & Shoulders Dual Sachets Pack	PSN	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1043014	zinc pyrithione 0.5 % Medicated Conditioner	PSN	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1043014	zinc pyrithione 0.5 % Medicated Conditioner	PSN	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1441653	zinc pyrithione 1 % Medicated Shampoo (10 ML) / zinc pyrithione 0.5 % Medicated Conditioner (10 ML) Pack	PSN	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1043244	zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1043244	zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1044465	zinc pyrithione 5 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1044465	zinc pyrithione 5 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1043014	zinc pyrithione 5 MG/ML Medicated Shampoo	SCD	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1043014	zinc pyrithione 5 MG/ML Medicated Shampoo	SCD	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1044465	Head & Shoulders 0.5 % Conditioner	SY	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1044465	Head & Shoulders 0.5 % Conditioner	SY	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1043244	Head & Shoulders 1 % Medicated Shampoo	SY	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1043244	Head & Shoulders 1 % Medicated Shampoo	SY	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1043244	Head & Shoulders 10 MG/ML Medicated Shampoo	SY	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1043244	Head & Shoulders 10 MG/ML Medicated Shampoo	SY	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1044465	Head & Shoulders 5 MG/ML Medicated Shampoo	SY	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1044465	Head & Shoulders 5 MG/ML Medicated Shampoo	SY	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1441654	Head & Shoulders Dual Sachets Pack	SY	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1441654	Head & Shoulders Dual Sachets Pack (1 (0.34 FL OZ) (zinc pyrithione 1 % Medicated Shampoo [Head & Shoulders]) / 1 (0.34 FL OZ) (zinc pyrithione 0.5 % Medicated Conditioner [Head & Shoulders]))	SY	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
1043014	zinc pyrithione 0.5 % Medicated Shampoo	SY	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
1043014	zinc pyrithione 0.5 % Medicated Shampoo	SY	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
209884	zinc pyrithione 1 % Medicated Conditioner	SY	19ad72ea-9a4b-0a35-e063-6394a90a9131	2
209884	zinc pyrithione 1 % Medicated Conditioner	SY	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
209884	zinc pyrithione 1 % Medicated Shampoo	SY	7a2c32f7-182b-8959-e053-2991aa0a3a12	2
209884	zinc pyrithione 1 % Medicated Shampoo	SY	19ad72ea-9a4b-0a35-e063-6394a90a9131	2

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
69423-103-59	69423010359	592 mL in 1 BOTTLE, PLASTIC (69423-103-59)	592 ml	2022-12-15	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Head and Shoulders ® Dual Kit Smooth and Silky	The Procter & Gamble Manufacturing Company	2025-12-31	HUMAN OTC DRUG LABEL	2
Head and Shoulders ® Conditioner Smooth & Silky	The Procter & Gamble Manufacturing Company	2025-12-18	HUMAN OTC DRUG LABEL	12
Head and Shoulders ® Dual Kit Smooth and Silky	The Procter & Gamble Manufacturing Company	2025-05-14	HUMAN OTC DRUG LABEL	4
Head and Shoulders ® Dual Sachets Smooth and Silky	The Procter & Gamble Manufacturing Company	2020-01-09	HUMAN OTC DRUG LABEL	2