Head and Shoulders Supreme Detox and Hydrate

Product NDC: 69423-343
11-digit product format: 694230343
Labeler code: 69423
Product ID: 69423-343_46409e50-bdcf-7c1f-e063-6294a90a1602
Type: HUMAN OTC DRUG
Nonproprietary name: Pyrithione Zinc
Dosage form: SHAMPOO
Route: TOPICAL
Labeler: The Procter & Gamble Manufacturing Company
Application: M032
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2019-05-01
Substance: PYRITHIONE ZINC
Active strength: 1 g/100mL
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	69423-343	69423-343-01	D	Discontinued by firm		2026-10-15

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source date	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Head and Shoulders Supreme Detox and Hydrate
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
PYRITHIONE ZINC	1 g/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
R953O2RHZ5	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
209884	Internal RxNorm lookup
1043244	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
8659218e-cb8d-bb44-e053-2a91aa0ae37b	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
d5e51f11-ad28-caa4-4b49-4143974782ad	Product name	1	20150831

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
69423-343-01	Head and Shoulders Supreme Detox and Hydrate	2 in 1 CELLO PACK	SHAMPOO	2	8
69423-343-01	Head and Shoulders Supreme Detox and Hydrate	350 mL in 1 BOTTLE, PUMP	SHAMPOO	350	8
69423-343-35	Head and Shoulders Supreme Detox and Hydrate	350 mL in 1 BOTTLE, PUMP	SHAMPOO	350	8

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
69423-343	HEAD AND SHOULDERS SUPREME DETOX AND HYDRATE (PYRITHIONE ZINC) SHAMPOO [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	7	Current NDC, Legacy NDC, 3 package rows	20241129_8659218e-cb8d-bb44-e053-2a91aa0ae37b.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 10 of 31 · 615 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Dry Scalp	PYRITHIONE ZINC	Valu Merchandisers Company	6349fd91-675b-4489-8b57-e584f718ca3f	2026-02-16	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp Care	PYRITHIONE ZINC	Valu Merchandisers Company	e9fc676c-0313-430f-a422-6dba51241bd5	2026-02-16	Warnings, Adverse reactions	Exact identifier application number: M032
Dandruff	PYRITHIONE ZINC	Valu Merchandisers Company	d5dd333d-fea5-4e03-bd9f-cbc28ea48a80	2026-02-16	Warnings, Adverse reactions	Exact identifier application number: M032
Dandruff	PYRITHIONE ZINC	United Natural Foods, Inc. dba UNFI	66f301bf-8e2e-43ce-b6b8-0983fe795f01	2026-02-16	Warnings, Adverse reactions	Exact identifier application number: M032
Tuymec Anti-Dandruff Shampoo.	ANTI-DANDRUFF SHAMPOO.	Guangzhou Jingliang Cosmetics Co., Ltd.	4ae93408-5c8f-c0a5-e063-6394a90a9e0d	2026-02-15	Warnings	Exact identifier application number: M032
RoyceDerm Seborrheic Dermatitis and Psoriasis Treatment cream	SALICYLIC ACID 3%	RoyceDerm LLC	4ac42528-9210-6936-e063-6294a90a4168	2026-02-14	Warnings	Exact identifier application number: M032
OLIVITA 5% Minoxidil	5% MINOXIDIL	Shenzhen Xinxin Yunhai Technology Co., Ltd.	4acbdf3d-976a-2cba-e063-6294a90a35e6	2026-02-14	Warnings	Exact identifier application number: M032
VENANOCI Minoxidil	MINOXIDIL	Shenzhen Xinxin Yunhai Technology Co., Ltd.	4acc38aa-13da-981b-e063-6294a90aede5	2026-02-14	Warnings	Exact identifier application number: M032
Everyday Clean Dandruff	PYRITHIONE ZINC	Topco Associates LLC	fc568c8f-0d59-4b26-8f72-ea70e4316687	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M032
Dandruff	PYRITHIONE ZINC	Topco Associates LLC	a0f2c58b-bb17-42a3-bd90-be771f60ef20	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M032
Dandruff	PYRITHIONE ZINC	Topco Associates LLC	706b856c-ce89-4860-bc5d-9803deb469e7	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp Care	PYRITHIONE ZINC	Topco Associates LLC	3300bfd5-ae84-4bc8-a4cd-05472b498fb7	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M032
Everyday Clean	PYRITHIONE ZINC	Topco Associates LLC	c0abb41f-9df0-4493-8452-592ec30c7924	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M032
2 in 1 Dandruff	PYRITHIONE ZINC	Topco Associates LLC	7da1e057-a69e-4b89-a309-919d88da3b93	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M032
Pyrithione zinc	PYRITHIONE ZINC	Topco Associates LLC	2c1420a8-404f-4fd7-8f07-cd441b390ac2	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M032
Everyday Clean Dandruff	PYRITHIONE ZINC	WinCo Foods, LLC	2581c531-c068-4dae-b569-3b1f86dad066	2026-02-12	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp	PYRITHIONE ZINC	WinCo Foods, LLC	4fca1200-dc6c-4e6e-b09c-2ec8ac0fa411	2026-02-12	Warnings, Adverse reactions	Exact identifier application number: M032
Everyday Clean 2 in 1	PYRITHIONE ZINC	WinCo Foods, LLC	8bd391ae-0eeb-4e7d-b1e5-20e4adb1da17	2026-02-12	Warnings, Adverse reactions	Exact identifier application number: M032
Everyday Clean 2 in 1	PYRITHIONE ZINC	Your Military Exchanges	a62b282f-e928-42bb-b595-d5f2066aac63	2026-02-12	Warnings, Adverse reactions	Exact identifier application number: M032
natouch	PYRITHIONE ZINC	Natouch LLC	0f330e2d-25d7-5e0e-e063-6394a90acda9	2026-02-10	Warnings	Exact identifier application number: M032

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R953O2RHZ5	PYRITHIONE ZINC	13463-41-7	PYRITHIONE ZINC

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1043244	head & shoulders 1 % Medicated Shampoo	PSN	8659218e-cb8d-bb44-e053-2a91aa0ae37b	8
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	8659218e-cb8d-bb44-e053-2a91aa0ae37b	8
1043244	zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	8659218e-cb8d-bb44-e053-2a91aa0ae37b	8
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	8659218e-cb8d-bb44-e053-2a91aa0ae37b	8
1043244	Head & Shoulders 1 % Medicated Shampoo	SY	8659218e-cb8d-bb44-e053-2a91aa0ae37b	8
1043244	Head & Shoulders 10 MG/ML Medicated Shampoo	SY	8659218e-cb8d-bb44-e053-2a91aa0ae37b	8
209884	zinc pyrithione 1 % Medicated Conditioner	SY	8659218e-cb8d-bb44-e053-2a91aa0ae37b	8
209884	zinc pyrithione 1 % Medicated Shampoo	SY	8659218e-cb8d-bb44-e053-2a91aa0ae37b	8

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
69423-343-01	69423034301	2 BOTTLE, PUMP in 1 CELLO PACK (69423-343-01) > 350 mL in 1 BOTTLE, PUMP		2020-01-01	0000-00-00	No	No	Current
69423-343-35	69423034335	350 mL in 1 BOTTLE, PUMP (69423-343-35)	350 ml	2019-05-02	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Head and Shoulders ® Supreme Detox and Hydrate Shampoo	The Procter & Gamble Manufacturing Company	2025-12-18	HUMAN OTC DRUG LABEL	8