Head and Shoulders Apple Cider Vinegar 2in1

Product NDC: 69423-522
11-digit product format: 694230522
Labeler code: 69423
Product ID: 69423-522_46411d20-a5fe-3d6d-e063-6294a90ae80c
Type: HUMAN OTC DRUG
Nonproprietary name: Pyrithione Zinc
Dosage form: LOTION/SHAMPOO
Route: TOPICAL
Labeler: The Procter & Gamble Manufacturing Company
Application: M032
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2020-11-17
Substance: PYRITHIONE ZINC
Active strength: 1 g/100mL
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	69423-522	69423-522-12	D	Discontinued by firm		2026-10-12
excluded package	package	69423-522	69423-522-40	D	Discontinued by firm		2026-10-12

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 21 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	69423-522-12	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	69423-522-40	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	69423-522-12	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	69423-522-40	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	69423-522-12	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	69423-522-40	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	69423-522-12	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	69423-522-40	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	69423-522-12	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	69423-522-40	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	69423-522-12	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	69423-522-40	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	69423-522-12	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	69423-522-40	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	69423-522-12	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	69423-522-40	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	69423-522-12	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	69423-522-40	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	69423-522-12	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	69423-522-12	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	69423-522-12	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Head and Shoulders Apple Cider Vinegar 2in1
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
PYRITHIONE ZINC	1 g/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
R953O2RHZ5	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
209884	Internal RxNorm lookup
1043244	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
b698b310-a794-e7f3-e053-2a95a90a47c4	Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
69423-522-12	2023-01-31	C162847	48780-1	f386c64a-0f01-0266-e053-dadaa90a7c1a	Head and Shoulders ® Apple Cider Vinegar 2in1
69423-522-40	2023-01-31	C162847	48780-1	f386c64a-0f01-0266-e053-dadaa90a7c1a	Head and Shoulders ® Apple Cider Vinegar 2in1

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
69423-522-12	Head and Shoulders Apple Cider Vinegar 2in1	1280 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	1280	6
69423-522-37	Head and Shoulders Apple Cider Vinegar 2in1	370 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	370	6
69423-522-40	Head and Shoulders Apple Cider Vinegar 2in1	400 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	400	6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
69423-522	HEAD AND SHOULDERS APPLE CIDER VINEGAR 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	5	Current NDC, Legacy NDC, 3 package rows	20241128_b698b310-a794-e7f3-e053-2a95a90a47c4.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 20 of 31 · 615 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Structure of Skin Soothing Anti-Dandruff	PYRITHIONE ZINC	STRUCTURE OF SKIN LLC	3311fa83-a06b-b379-e063-6394a90ae269	2025-04-18	Warnings	Exact identifier application number: M032
LILIVERA Hair Regrowth Kit	MINOXIDIL	Guangzhou Haishi Biological Technology Co., Ltd.	330602da-ec17-5a35-e063-6394a90a741b	2025-04-17	Warnings	Exact identifier application number: M032
Head and Shoulders Clinical Strength Dry Scalp Rescue	SELENIUM SULFIDE	The Procter & Gamble Manufacturing Company	3272a482-3813-63e4-e063-6394a90a43eb	2025-04-10	Warnings	Exact identifier application number: M032
XtraCare Anti-Dandruff Hair Cleanse for normal hair	PYRITHIONE ZINC	Rejoice International Inc.	b90e574c-933c-4f86-aadc-567ffbe6ea04	2025-04-09	Warnings	Exact identifier application number: M032
XtraCare Anti-Dandruff Hair Cleanse for sensitive hair	PYRITHIONE ZINC	Rejoice International Inc.	979394c2-5681-44c8-a43c-bf3a392bd0c1	2025-04-09	Warnings	Exact identifier application number: M032
LEAHUE MADHUCA TONIC	SALICYLIC ACID	Bio-interchange Co.	31ee4645-0f64-f7a0-e063-6394a90a1736	2025-04-04	Warnings	Exact identifier application number: M032
LEAHUE MADHUCA	SALICYLIC ACID	Bio-interchange Co.	81470dfe-f063-9d16-e053-2a91aa0a1829	2025-04-04	Warnings	Exact identifier application number: M032
Kenkoderm Psoriasis Moisturizing	SALICYLIC ACID	Nexgel,Inc.	31ce20a2-95ae-e424-e063-6394a90af18a	2025-04-01	Warnings	Exact identifier application number: M032
Kenkoderm Psoriasis	SALICYLIC ACID	Nexgel,Inc.	31cf90e5-0f21-903d-e063-6394a90a075d	2025-04-01	Warnings	Exact identifier application number: M032
nioxin PRO CLINICAL SCALP RECOVERY scalp soothing serum	PYRITHIONE ZINC	The Wella Corporation	31af9365-e1a3-7203-e063-6294a90a8ade	2025-03-31	Warnings	Exact identifier application number: M032
Listarfe Anti-Dandruff Shampoo.	ANTI-DANDRUFF SHAMPOO	Guangzhou Zanming Trading Co., Ltd.	3163eee0-379f-1f88-e063-6294a90a58ce	2025-03-28	Warnings	Exact identifier application number: M032
anti dandruff SHAMPOOS	PYRITHIONE ZINC	Guangdong Quaker Daily Chemical Co., LTD	31392f0f-a6c4-1cfb-e063-6294a90a4d36	2025-03-26	Warnings	Exact identifier application number: M032
anti dandruff SHAMPOOS	PYRITHIONE ZINC	Guangdong Quaker Daily Chemical Co., LTD	313716f7-6dd2-e1c5-e063-6394a90a9de3	2025-03-25	Warnings	Exact identifier application number: M032
CeraVe Anti Dandruff Hydrating	PYRITHIONE ZINC	L'Oreal USA Products Inc	422e743b-fd77-40ed-8c5d-7f05112a447f	2025-03-24	Warnings	Exact identifier application number: M032
Scalp Revival	SALICYLIC ACID 3%	Beccair, LLC	0a77e90e-a33a-43f3-80a0-a16a6902a735	2025-03-21	Warnings	Exact identifier application number: M032
Gold Bond Psoriasis Relief Medicated Multi-Symptom	SALICYLIC ACID	Chattem, Inc.	e8479bbc-5f49-41f2-851e-a93543516639	2025-03-19	Warnings	Exact identifier application number: M032
13.5oz 2 In 1 Dandruff Hair Cleanse and Conditioner - Eucalyptus and Mint	PYRITHIONE ZINC	Rejoice International Corp.	308554c2-938b-f0b5-e063-6394a90a5bfa	2025-03-17	Warnings	Exact identifier application number: M032
13.5oz 2 In 1 Dandruff Hair Cleanse and Conditioner - Shea and Cocoa Butter	PYRITHIONE ZINC	Rejoice International Corp.	3086d31e-54ef-9c0f-e063-6394a90abdff	2025-03-17	Warnings	Exact identifier application number: M032
SA Scalp Therapy	SA SCALP	Milbar Laboratories	304db1ab-acd7-43d5-e063-6294a90aeec2	2025-03-14	Warnings	Exact identifier application number: M032
Neutrogena Scalp Therapy Anti-Dandruff Itchy Scalp	SALICYLIC ACID	Kenvue Brands LLC	ca4c0d63-50b3-169f-e053-2a95a90acbcd	2025-03-10	Warnings	Exact identifier application number: M032

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R953O2RHZ5	PYRITHIONE ZINC	13463-41-7	PYRITHIONE ZINC

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1043244	head & shoulders 1 % Medicated Shampoo	PSN	b698b310-a794-e7f3-e053-2a95a90a47c4	6
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	b698b310-a794-e7f3-e053-2a95a90a47c4	6
1043244	zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	b698b310-a794-e7f3-e053-2a95a90a47c4	6
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	b698b310-a794-e7f3-e053-2a95a90a47c4	6
1043244	Head & Shoulders 1 % Medicated Shampoo	SY	b698b310-a794-e7f3-e053-2a95a90a47c4	6
1043244	Head & Shoulders 10 MG/ML Medicated Shampoo	SY	b698b310-a794-e7f3-e053-2a95a90a47c4	6
209884	zinc pyrithione 1 % Medicated Conditioner	SY	b698b310-a794-e7f3-e053-2a95a90a47c4	6
209884	zinc pyrithione 1 % Medicated Shampoo	SY	b698b310-a794-e7f3-e053-2a95a90a47c4	6

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
69423-522-12	69423052212	1280 mL in 1 BOTTLE, PUMP (69423-522-12)	1280 ml	2021-10-01	0000-00-00	No	No	Current
69423-522-37	69423052237	370 mL in 1 BOTTLE, PLASTIC (69423-522-37)	370 ml	2022-12-15		No	No	Current
69423-522-40	69423052240	400 mL in 1 BOTTLE, PLASTIC (69423-522-40)	400 ml	2020-11-17	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Head and Shoulders ® Apple Cider Vinegar 2in1	The Procter & Gamble Manufacturing Company	2025-12-18	HUMAN OTC DRUG LABEL	6