Head and Shoulders 2in1 Clinical Strength Dandruff Defense Intensive Itch Relief
- Product NDC
- 69423-527
- Requested package NDC
- 69423-527-40
- 11-digit product format
- 694230527
- Labeler code
- 69423
- Product ID
- 69423-527_474471ad-d351-8ad1-e063-6294a90a67db
- Type
- HUMAN OTC DRUG
- Nonproprietary name
- Selenium Sulfide
- Dosage form
- LOTION/SHAMPOO
- Route
- TOPICAL
- Labeler
- The Procter & Gamble Manufacturing Company
- Application
- M032
- Marketing category
- OTC MONOGRAPH DRUG
- Marketing start
- 2020-11-17
- Marketing end
- 2026-12-01
- Substance
- SELENIUM SULFIDE
- Active strength
- 1 g/100mL
- NDC exclude flag
- No
- Current FDA listing
- Yes
Observed NDC auxiliary status history#
This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
| Captured / source date | Dataset | Scope | Product NDC | Package NDC | Code | Status | Reporting period | Archive | Snapshot | Source SHA-256 |
|---|---|---|---|---|---|---|---|---|---|---|
| 2022-08-30 03:57 UTC · source 2022-08-29 | excluded package | package | 69423-527 | 69423-527-40 | I | Inactivated by FDA | excluded / ndc_excluded.zip | fb8cb913e6d1… | eb8c232b6be0… | |
| 2022-04-09 23:13 UTC · source 2022-04-08 | excluded package | package | 69423-527 | 69423-527-40 | I | Inactivated by FDA | excluded / ndc_excluded.zip | 86f5da6cb304… | a595104c45d7… | |
| 2022-04-04 05:40 UTC · source 2022-04-01 | excluded package | package | 69423-527 | 69423-527-40 | I | Inactivated by FDA | excluded / ndc_excluded.zip | bd6a592717d7… | 303034d00443… |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
- Finished product
- Yes
- Brand name base
- Head and Shoulders 2in1 Clinical Strength Dandruff Defense Intensive Itch Relief
Active Ingredients#
| Ingredient | Strength |
|---|---|
| SELENIUM SULFIDE | 1 g/100mL |
Harmonized UNII identifiers#
| Identifier | FDA.report destination |
|---|---|
| Z69D9E381Q | Internal UNII lookup |
Harmonized RxCUI identifiers#
Harmonized SPL set identifiers#
| Identifier | FDA.report destination |
|---|---|
| b6ada541-f12b-76f2-e053-2a95a90a5286 | Available on FDA.report |
FDA-Initiated Inactive NDC Indexing#
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 69423-527-40 | 2023-03-24 | C162847 | 48780-1 | d6a99b3a-00f2-a426-e053-dadaa90af4c2 | Head and Shoulders ® 2in1 Clinical Strength Dandruff Defense Intensive Itch Relief |
| 69423-527-40 | 2022-01-28 | C162847 | 48780-1 | d6a99b3a-00f2-a426-e053-dadaa90af4c2 | Head and Shoulders ® 2in1 Clinical Strength Dandruff Defense Intensive Itch Relief |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 69423-527-40 | Head and Shoulders 2in1 Clinical Strength Dandruff Defense Intensive Itch Relief | 400 mL in 1 BOTTLE, PLASTIC | LOTION/SHAMPOO | 400 | 4 |
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 69423-527 | HEAD AND SHOULDERS 2IN1 CLINICAL STRENGTH DANDRUFF DEFENSE INTENSIVE ITCH RELIEF (SELENIUM SULFIDE) LOTION/SHAMPOO [THE PROCTER & GAMBLE MANUFACTURING COMPANY] | 3 | Current NDC, Legacy NDC, 1 package rows | 20241027_b6ada541-f12b-76f2-e053-2a95a90a5286.zip |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Leader Classic Clean Dandruff | PYRITHIONE ZINC | CARDINAL HEALTH 110, LLC. DBA LEADER | 5b22537d-d09c-5bd6-e063-6294a90a48ff | 2026-09-10 | Warnings | M032 |
| Head and Shoulders Bare Minimal Ingredients Pure Clean 2in1 | PYRITHIONE ZINC | The Procter & Gamble Manufacturing Company | 2cc726c2-3747-6dbf-e063-6294a90a789f | 2026-09-09 | Warnings | M032 |
| Leader Maximum Strength Therapeutic Dandruff | SALICYLIC ACID | CARDINAL HEALTH 110, LLC. DBA LEADER | 5afb2260-5b50-de95-e063-6394a90a5a47 | 2026-09-08 | Warnings | M032 |
| ANTI-DANDRUFF | KETOCONAZOLE | Guangzhou ChuanMa International Trading Co.,Ltd. | 5ac93feb-eb6d-7563-e063-6294a90ad2e0 | 2026-09-05 | Warnings | M032 |
| Dr Marvel ANTI DANDRUFF SCALP SERUM | SELENIUM SULFIDE SALICYLIC ACID | Guangzhou Liyan Cosmetics Technology Co., Ltd. | 5aaeddff-72f9-3687-e063-6394a90ae5dc | 2026-09-04 | Warnings | M032 |
| Head and Shoulders Scalp Restore Nourishing Conditioner | PYRITHIONE ZINC | The Procter & Gamble Manufacturing Company | 5a834d00-cc79-1a8e-e063-6294a90ab245 | 2026-09-02 | Warnings | M032 |
| Head and Shoulders Scalp Purify Clarifying Pre-Shampoo | SALICYLIC ACID | The Procter & Gamble Manufacturing Company | 5a84c545-4570-b078-e063-6394a90a8c5a | 2026-09-02 | Warnings | M032 |
| Head and Shoulders Scalp Purify Volumizing | SALICYLIC ACID | The Procter & Gamble Manufacturing Company | 5a8627ec-cfd8-d0f6-e063-6394a90ab488 | 2026-09-02 | Warnings | M032 |
| Head and Shoulders Scalp Soothe Cooling | SALICYLIC ACID | The Procter & Gamble Manufacturing Company | 5a87ed71-87e7-a7b7-e063-6294a90ac897 | 2026-09-02 | Warnings | M032 |
| Head and Shoulders Scalp Restore Nourishing | PYRITHIONE ZINC | The Procter & Gamble Manufacturing Company | 5a8a42d2-8610-1dfb-e063-6294a90abc7a | 2026-09-02 | Warnings | M032 |
| Koi Beauty 5% Minoxidil Hair Growth Kit | 5% MINOXIDIL HAIR GROWTH KIT | Beijing Sea Heart International Science And Technology Co.,Ltd. | 3b34f263-1232-4bb9-e063-6294a90a494d | 2026-08-27 | Warnings | M032 |
| SMOOTH AND SOFT DANDRUFF | PYRITHIONE ZINC | Universal Distribution Center LLC | 9e235139-07a2-469a-8601-db69379ce347 | 2026-08-24 | Warnings | M032 |
| ITCHY SCALP RELIEF DANDRUFF | PYRITHIONE ZINC | Universal Distribution Center LLC | 634019c2-03a3-4fed-939e-6f9a50ddea7b | 2026-08-24 | Warnings | M032 |
| Minoxidil Hair Regrowth Treatment | MINOXIDIL | Shenzhen Earth Surface Trading Co., Ltd. | 59b4f9e3-c241-6a70-e063-6294a90a364f | 2026-08-23 | Warnings | M032 |
| Minoxidil Hair Regrowth Treatment | MINOXIDIL | Shenzhen Earth Surface Trading Co., Ltd. | 59b52a52-dab0-87b5-e063-6294a90a0596 | 2026-08-23 | Warnings | M032 |
| Minoxidil Hair Regrowth Treatment | MINOXIDIL | Shenzhen Earth Surface Trading Co., Ltd. | 59b67ce0-3546-c18a-e063-6394a90ae50a | 2026-08-23 | Warnings | M032 |
| Anti Dandruff | KETOCONAZOLE | Guangzhou ChuanMa International Trading Co.,Ltd. | 599f2cce-0c27-d425-e063-6394a90a1565 | 2026-08-22 | Warnings | M032 |
| Anti Dandruff | KETOCONAZOLE | Guangzhou ChuanMa International Trading Co.,Ltd. | 59a0a062-92d1-210a-e063-6394a90a9bf9 | 2026-08-22 | Warnings | M032 |
| Ouai Anti-Dandruff | SALICYLIC ACID | The Procter & Gamble Manufacturing Company | 5990c45f-f653-b403-e063-6394a90a329d | 2026-08-21 | Warnings | M032 |
| Dermatology Psoriasis Cream | COAL TAR | G.M.J Natural Products, Inc. | 96cc5455-f3b8-4ded-a158-5de209d7bf0d | 2026-08-21 | Warnings | M032 |
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | DailyMed | SPL version |
|---|---|---|---|---|
| 1549328 | Head & Shoulders Clinical Strength 1 % Medicated Shampoo | PSN | b6ada541-f12b-76f2-e053-2a95a90a5286 | 4 |
| 204642 | selenium sulfide 1 % Medicated Shampoo | PSN | b6ada541-f12b-76f2-e053-2a95a90a5286 | 4 |
| 1549328 | selenium sulfide 10 MG/ML Medicated Shampoo [Head & Shoulders Clinical Strength] | SBD | b6ada541-f12b-76f2-e053-2a95a90a5286 | 4 |
| 204642 | selenium sulfide 10 MG/ML Medicated Shampoo | SCD | b6ada541-f12b-76f2-e053-2a95a90a5286 | 4 |
| 1549328 | Head & Shoulders Clinical Solutions 10 MG/ML Medicated Shampoo | SY | b6ada541-f12b-76f2-e053-2a95a90a5286 | 4 |
| 1549328 | Head & Shoulders Clinical Strength 10 MG/ML Medicated Shampoo | SY | b6ada541-f12b-76f2-e053-2a95a90a5286 | 4 |
| 204642 | selenium sulfide 1 % Lotion Shampoo | SY | b6ada541-f12b-76f2-e053-2a95a90a5286 | 4 |
| 204642 | selenium sulfide 1 % Medicated Shampoo | SY | b6ada541-f12b-76f2-e053-2a95a90a5286 | 4 |
| 1549328 | selenium sulfide 10 MG/ML Medicated Shampoo [Head & Shoulders Clinical Solutions] | SY | b6ada541-f12b-76f2-e053-2a95a90a5286 | 4 |
Packages#
| Package NDC | 11-digit format | Description | Units | Marketing start | Marketing end | Sample | Exclude flag | Status |
|---|---|---|---|---|---|---|---|---|
| 69423-527-40 | 69423052740 | 400 mL in 1 BOTTLE, PLASTIC (69423-527-40) | 400 ml | 2020-11-17 | 2026-12-01 | No | No | Current |