Naproxen Sodium

Product NDC
69452-179
11-digit product format
694520179
Labeler code
69452
Product ID
69452-179_0d85dc59-4954-47fc-e063-6394a90a01cd
Type
HUMAN OTC DRUG
Nonproprietary name
Naproxen Sodium
Dosage form
CAPSULE, LIQUID FILLED
Route
ORAL
Labeler
Bionpharma Inc.
Application
NDA021920
Marketing category
NDA
Marketing start
2018-11-01
Substance
NAPROXEN SODIUM
Active strength
220 mg/1
Pharmacologic classes
Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Nonsteroidal Anti-inflammatory Drug [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

NDC auxiliary status#

Explicit status records from FDA unfinished, excluded, and compounder auxiliary files. Absence of a row is not itself a regulatory status. Browse every current auxiliary row, including rows without a usable NDC. · Browse every captured source and parsed snapshot.

Current NDC status page 1 of 1 · 5 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage69452-17969452-179-11DDiscontinued by firm2026-08-03
excluded packagepackage69452-17969452-179-15DDiscontinued by firm2026-08-03
excluded packagepackage69452-17969452-179-20DDiscontinued by firm2026-08-03
excluded packagepackage69452-17969452-179-78DDiscontinued by firm2026-08-03
excluded packagepackage69452-17969452-179-79DDiscontinued by firm2026-08-03

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021920-001NAPROXEN SODIUMNAPROXEN SODIUMEQ 200MG BASECAPSULE / ORALRLD, RS2006-02-17

Orange Book patents#

Current patent rows page 1 of 1 · 8 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N021920-001100223442026-03-03U-1731Drug product2018-07-23
N021920-001100223442026-03-03U-1732Drug product2018-07-23
N021920-001100289252026-03-03U-1731Drug product2018-07-24
N021920-001100289252026-03-03U-1732Drug product2018-07-24
N021920-001110902802026-03-03U-1731Drug product2021-08-24
N021920-001110902802026-03-03U-1732Drug product2021-08-24
N021920-00196939782026-03-03Drug product2017-11-13
N021920-00196939792026-03-03Drug product2017-11-13

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06N021920-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORALRLD, RS2006-02-17a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-01 22:54:322026-06N021920-001100223442026-03-03U-1731Drug product2018-07-23a50c72e98297…
2026-08-01 22:54:322026-06N021920-001100223442026-03-03U-1732Drug product2018-07-23a50c72e98297…
2026-08-01 22:54:322026-06N021920-001100289252026-03-03U-1731Drug product2018-07-24a50c72e98297…
2026-08-01 22:54:322026-06N021920-001100289252026-03-03U-1732Drug product2018-07-24a50c72e98297…
2026-08-01 22:54:322026-06N021920-001110902802026-03-03U-1731Drug product2021-08-24a50c72e98297…
2026-08-01 22:54:322026-06N021920-001110902802026-03-03U-1732Drug product2021-08-24a50c72e98297…
2026-08-01 22:54:322026-06N021920-00196939782026-03-03Drug product2017-11-13a50c72e98297…
2026-08-01 22:54:322026-06N021920-00196939792026-03-03Drug product2017-11-13a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 2 · 22 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
naproxen sodiumNAPROXEN SODIUMBionpharma Inc.9343c79f-9994-4599-bcfe-0a93e49d726e2026-05-12WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMAmazon.com Services LLC04a298dc-c525-8198-e063-6294a90a6f962026-04-27WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
naproxen sodiumNAPROXEN SODIUMBionpharma Inc.ba4f927a-4bbe-0d87-e053-2995a90a8c202026-04-20WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMMEIJER DISTRIBUTION INC89f82399-9f71-49dd-8710-b60f346c576c2025-12-12WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMTARGET Corporation36bf8594-9303-c816-e063-6294a90af7052025-12-08WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
AleveNAPROXEN SODIUMBayer HealthCare LLC.1266393e-b55e-4e34-9710-0b87209f41582025-12-04WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Aleve Easy Open Arthritis CapNAPROXEN SODIUMBayer HealthCare LLC.3b5442c6-c6e1-4df3-8cec-40bbb4ec469f2025-12-04WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMAlbertsons Companiesf9df7495-9da7-8838-e053-6294a90a6fda2024-09-30WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMAMERISOURCE BERGEN16b3bbee-4881-b439-e063-6394a90a7c8f2024-04-22WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMBionpharma Inc.3e10256f-0a5f-49e4-9518-a72b10490f892023-12-27WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
ndc (product): 69452-179
Naproxen SodiumNAPROXEN SODIUMVALU MERCHANDISERS COMPANYfed305f1-e32d-e1ff-e053-6294a90a273d2023-10-03WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMRite Aid Corporationa359c47e-e2b4-5560-e053-2a95a90a28442023-03-03WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMKROGER COMPANY7487e685-ea64-43a2-9a4e-f5278840be042022-12-29WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMWal-Mart Stores, Inc.073ecef7-f5b1-4ee0-98bc-82972e3d84f92022-12-29WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMWALGREEN COMPANYa13bd208-f29f-1cbc-e053-2995a90a08ba2022-12-29WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMHEBdf8ea301-c48b-4da4-9e8e-5c69cac6cba72022-12-29WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMTOP CARE (Topco Associates LLC)c62b7fa0-5ae9-276c-e053-2995a90ade252022-12-29WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMCHAIN DRUG MARKETING ASSOCIATION INC.c482db41-b115-c24f-e053-2a95a90a29472022-12-21WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMWALGREEN COMPANY462a7e41-b899-4e08-8113-b48ece0ad8d82022-03-17WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920
Naproxen SodiumNAPROXEN SODIUMDISCOUNT DRUG MART, INC.b00c0e86-4c0b-45bf-948f-824ea0f09e392022-03-16WarningsExact identifier
application applno (NDA): 021920
application number: NDA021920

Additional Listing Data#

Finished product
Yes
Brand name base
Naproxen Sodium
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
NAPROXEN SODIUM220 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9TN87S3A3CInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1112231Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
3e10256f-0a5f-49e4-9518-a72b10490f89Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
fef6ad89-235f-4274-ba49-a8e53642473eProduct name220250225
87fed3e6-8fba-48ef-96b0-3a7fb54b96ffProduct name320230306
a62a50ac-1535-4461-9768-8ae703e2e9fbProduct name120210525
f52be47f-7aa7-46c0-b1fa-50c18dd50206Product name120201029
b5fdaaec-7251-4da6-9cb2-4e9e76939ec8Product name120200623
444b3e50-f226-46ef-bfca-2e7035d140cdProduct name120190611
e76dbbc1-775d-722c-08ff-ed45e8a80defProduct name320181002
7cda52fc-125f-421c-8fea-bc1974370c49Product name220180703
597b1cfd-7b31-5048-62be-ca5cd740da2fProduct name120140508
6f4f4521-fd56-1ae6-888b-3b021bd75c7cProduct name120140508
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508
bc07ef78-e82d-0c19-31f4-31f263780582Product name120140508
ce67e27d-1d21-5465-4409-b0662dd99d4dProduct name120140508
ec2149b3-5c6d-5344-f757-c86411073075Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
69452-179-11Naproxen Sodium20 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED205
69452-179-15Naproxen Sodium40 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED405
69452-179-20Naproxen Sodium100 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED1005
69452-179-22Naproxen Sodium120 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED1205
69452-179-78Naproxen Sodium80 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED805
69452-179-79Naproxen Sodium160 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED1605

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
69452-179NAPROXEN SODIUM CAPSULE, LIQUID FILLED [BIONPHARMA INC.]5Current NDC, Legacy NDC, 6 package rows20231228_3e10256f-0a5f-49e4-9518-a72b10490f89.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1112231naproxen sodium 220 MG Oral CapsulePSN3e10256f-0a5f-49e4-9518-a72b10490f895
1112231naproxen sodium 220 MG Oral CapsuleSCD3e10256f-0a5f-49e4-9518-a72b10490f895
1112231naproxen sodium 220 MG (as naproxen 200 MG) Oral CapsuleSY3e10256f-0a5f-49e4-9518-a72b10490f895

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
69452-179-116945201791120 in 1 BOTTLE, PLASTICHistorical
69452-179-156945201791540 in 1 BOTTLE, PLASTICHistorical
69452-179-2069452017920100 in 1 BOTTLE, PLASTICHistorical
69452-179-2269452017922120 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (69452-179-22) 2018-11-010000-00-00NoNoCurrent
69452-179-786945201797880 in 1 BOTTLE, PLASTICHistorical
69452-179-7969452017979160 in 1 BOTTLE, PLASTICHistorical