Bupivacaine hydrochloride

Product NDC
70069-752
11-digit product format
700690752
Labeler code
70069
Product ID
70069-752_2b24af95-6f20-4945-bf8c-742f1d6f2721
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Bupivacaine hydrochloride
Dosage form
INJECTION, SOLUTION
Route
INFILTRATION; PERINEURAL
Labeler
Somerset Therapeutics, LLC
Application
ANDA217792
Marketing category
ANDA
Marketing start
2023-11-27
Substance
BUPIVACAINE HYDROCHLORIDE
Active strength
2.5 mg/mL
Pharmacologic classes
Amide Local Anesthetic [EPC], Amides [CS], Local Anesthesia [PE]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217792-001BUPIVACAINE HYDROCHLORIDEBUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20
A217792-002BUPIVACAINE HYDROCHLORIDEBUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A217792-001AP
A217792-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20caaa826d4ba7…
2026-08-18 06:07:402026-07A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20d06236e962d9…
2024-10-29 15:01 UTC2024-10A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-2079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-2079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-201e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-201e350fbaab3a…
2024-05-31 18:47 UTC2024-05A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-208072bd15b7f6…
2024-05-31 18:47 UTC2024-05A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-208072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-206a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-206a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-201c564ffb4f44…
2024-02-18 07:12 UTC2024-02A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-201c564ffb4f44…
2023-12-20 04:57 UTC2023-12A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20ea1830bbd6c7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217792-001BUPIVACAINE HYDROCHLORIDE0.25%INJECTABLE / INJECTIONAP2023-11-20a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217792-002BUPIVACAINE HYDROCHLORIDE0.5%INJECTABLE / INJECTIONAP2023-11-20a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A217792-001AP1caaa826d4ba7…
2026-08-18 06:07:402026-07A217792-002AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A217792-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A217792-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217792-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217792-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217792-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A217792-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217792-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217792-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217792-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217792-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217792-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217792-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217792-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217792-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A217792-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A217792-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217792-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217792-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A217792-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A217792-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A217792-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A217792-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A217792-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A217792-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A217792-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A217792-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A217792-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A217792-002AP18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A217792-001AP16a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A217792-002AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A217792-001AP11c564ffb4f44…
2024-02-18 07:12 UTC2024-02A217792-002AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A217792-001AP1ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A217792-002AP1ea1830bbd6c7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217792-001AP1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217792-002AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Bupivacaine hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BUPIVACAINE HYDROCHLORIDE2.5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7TQO7W3VT8Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1012396Internal RxNorm lookup
1012404Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
bcaab86f-20f0-4482-8d73-e29b36dced58Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
cbf85893-59ef-423f-87d4-a573c000a8b9Product name820250731
5dad6767-dcd1-b0da-8727-7f3f7bc3a435Product name220250303
e3a99641-4540-4894-9108-00cab3c57b7eProduct name120211207
5da98533-f072-406b-9e1b-6ac19eca9926Product name120210622
306b993e-3140-4823-ad5e-88b708f9d2acProduct name120210510
a831e694-3663-4a83-82be-6c309429f750Product name220200608

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
70069-752-01Bupivacaine hydrochloride50 mL in 1 VIALINJECTION, SOLUTION504
70069-752-01Bupivacaine hydrochloride1 in 1 CARTONINJECTION, SOLUTION14
70069-752-10Bupivacaine hydrochloride50 mL in 1 VIALINJECTION, SOLUTION504
70069-752-10Bupivacaine hydrochloride10 in 1 CARTONINJECTION, SOLUTION104
70069-752-25Bupivacaine hydrochloride25 in 1 CARTONINJECTION, SOLUTION254
70069-752-25Bupivacaine hydrochloride50 mL in 1 VIALINJECTION, SOLUTION504

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
70069-752-01ML - Milliliter70069-752b38c7ef3-fe84-48b8-82fa-f8a0b7155e6a12024-07-12
70069-752-10ML - Milliliter70069-752a32d8834-b725-41fc-96e0-77f35c327b2612024-08-12
70069-752-25ML - Milliliter70069-752479a8cb8-5c4d-47d9-b547-02fd370f806412023-12-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
70069-752BUPIVACAINE HYDROCHLORIDE INJECTION, SOLUTION [SOMERSET THERAPEUTICS, LLC]4Current NDC, 6 package rows20240621_bcaab86f-20f0-4482-8d73-e29b36dced58.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Bupivacaine hydrochlorideBUPIVACAINE HYDROCHLORIDESomerset Therapeutics, LLCbcaab86f-20f0-4482-8d73-e29b36dced582024-06-20Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217792
application number: ANDA217792
ndc (product): 70069-752

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1012396BUPivacaine HCl 0.25 % Injectable SolutionPSNbcaab86f-20f0-4482-8d73-e29b36dced584
1012404BUPivacaine HCl 0.5 % Injectable SolutionPSNbcaab86f-20f0-4482-8d73-e29b36dced584
1012396bupivacaine hydrochloride 2.5 MG/ML Injectable SolutionSCDbcaab86f-20f0-4482-8d73-e29b36dced584
1012404bupivacaine hydrochloride 5 MG/ML Injectable SolutionSCDbcaab86f-20f0-4482-8d73-e29b36dced584
1012396bupivacaine hydrochloride 0.25 % Injectable SolutionSYbcaab86f-20f0-4482-8d73-e29b36dced584
1012404bupivacaine hydrochloride 0.5 % Injectable SolutionSYbcaab86f-20f0-4482-8d73-e29b36dced584

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
70069-752-01700690752011 VIAL in 1 CARTON (70069-752-01) / 50 mL in 1 VIAL1 vial2024-05-16NoNoCurrent
70069-752-107006907521010 VIAL in 1 CARTON (70069-752-10) / 50 mL in 1 VIAL10 vial2024-05-30NoNoCurrent
70069-752-257006907522525 VIAL in 1 CARTON (70069-752-25) / 50 mL in 1 VIAL25 vial2023-11-27NoNoCurrent