phytonadione

Product NDC
70121-1682
11-digit product format
701211682
Labeler code
70121
Product ID
70121-1682_a2f87d42-33cd-4706-bd3c-8b15c8095617
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
PHYTONADIONE
Dosage form
INJECTION, EMULSION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Labeler
Amneal Pharmaceuticals LLC
Application
ANDA216601
Marketing category
ANDA
Marketing start
2025-11-04
Substance
PHYTONADIONE
Active strength
1 mg/.5mL
Pharmacologic classes
Increased Prothrombin Activity [PE], Reversed Anticoagulation Activity [PE], Vitamin K [CS], Vitamin K [EPC], Warfarin Reversal Agent [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216601-001PHYTONADIONEPHYTONADIONE1MG/0.5MLINJECTABLE / INJECTIONAB12025-11-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A216601-001AB1

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A216601-001PHYTONADIONE1MG/0.5MLINJECTABLE / INJECTIONAB12025-11-04caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A216601-001PHYTONADIONE1MG/0.5MLINJECTABLE / INJECTIONAB2025-11-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216601-001PHYTONADIONE1MG/0.5MLINJECTABLE / INJECTIONAB2025-11-0431067a03dcf5…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216601-001PHYTONADIONE1MG/0.5MLINJECTABLE / INJECTIONAB12025-11-04a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A216601-001AB11caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A216601-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216601-001AB131067a03dcf5…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216601-001AB11a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
phytonadione
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PHYTONADIONE1 mg/.5mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
A034SE7857Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
727625Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2ce1dd90-11ad-4f74-af16-45b7e59f05daAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
16a2c1cd-ae95-d910-f03d-7e06b11dd243Product name520260202
653485de-0601-41e4-82db-7a60bb223e27Product name120251024
a21a21e5-f36d-4c1f-8918-def921b8f7e3Product name320250124
23fb3cda-2b50-f3d3-ebde-f542350bd77bProduct name420240828
081b54f0-4545-48b6-b854-03e1401f09eaProduct name120230112
48747306-602a-42cc-957b-5b0c69158eeeProduct name120180604
aead65a2-216e-4ff8-a178-44aab77c24edProduct name120180531
db5ebcdb-b6ae-21cd-4dc5-76cd84b5578bProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
70121-1682-1phytonadione1 in 1 TRAYINJECTION, EMULSION16
70121-1682-1phytonadione0.5 mL in 1 SYRINGE, GLASSINJECTION, EMULSION0.56
70121-1682-7phytonadione10 in 1 CARTONINJECTION, EMULSION106

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
70121-1682-1ML - Milliliter70121-168255298310-a997-48b9-ad0b-5fda54167d9a12026-03-17
70121-1682-7ML - Milliliter70121-16825f42a9ac-9eaf-4057-9db5-9c5f29a3b79212026-03-17

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
phytonadionePHYTONADIONEAmneal Pharmaceuticals LLC2ce1dd90-11ad-4f74-af16-45b7e59f05da2025-10-23Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216601
application number: ANDA216601
ndc (product): 70121-1682

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
727625phytonadione 1 MG in 0.5 ML Prefilled SyringePSN2ce1dd90-11ad-4f74-af16-45b7e59f05da6
7276250.5 ML vitamin K1 2 MG/ML Prefilled SyringeSCD2ce1dd90-11ad-4f74-af16-45b7e59f05da6
7276250.5 ML phytonadione 2 MG/ML Prefilled SyringeSY2ce1dd90-11ad-4f74-af16-45b7e59f05da6
727625phytonadione 1 MG per 0.5 ML Prefilled SyringeSY2ce1dd90-11ad-4f74-af16-45b7e59f05da6

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
70121-1682-1701211682011 in 1 TRAYHistorical
70121-1682-77012116820710 TRAY in 1 CARTON (70121-1682-7) / 1 SYRINGE, GLASS in 1 TRAY (70121-1682-1) / .5 mL in 1 SYRINGE, GLASS10 tray2025-11-04NoNoCurrent