Alka-Seltzer Original

Product NDC: 70264-014
11-digit product format: 702640014
Labeler code: 70264
Product ID: 70264-014_43c89573-4cf2-997f-e063-6394a90a76ca
Type: HUMAN OTC DRUG
Nonproprietary name: ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATE
Dosage form: TABLET, EFFERVESCENT
Route: ORAL
Labeler: R J General Corporation
Application: M013
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2010-03-02
Substance: ASPIRIN; SODIUM BICARBONATE; ANHYDROUS CITRIC ACID
Active strength: 325; 1916; 1000 mg/1; mg/1; mg/1
Pharmacologic classes: Acidifying Activity [MoA], Alkalinizing Activity [MoA], Anti-Inflammatory Agents, Non-Steroidal [CS], Anti-coagulant [EPC], Calcium Chelating Activity [MoA], Calculi Dissolution Agent [EPC], Cyclooxygenase Inhibitors [MoA], Decreased Coagulation Factor Activity [PE], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2022-08-30 03:57 UTC · source 2022-08-29	excluded product	product		`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	70264-014-01	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded product	product		`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	70264-014-01	`86f5da6cb304…`	`a595104c45d7…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded product	product		`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	70264-014-01	`bd6a592717d7…`	`303034d00443…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded product	product		`8dfbde2a14a4…`	`c9ff85d89658…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded package	package	70264-014-01	`8dfbde2a14a4…`	`c9ff85d89658…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded product	product		`e2bbac7714bc…`	`27bdfed8d636…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded package	package	70264-014-01	`e2bbac7714bc…`	`27bdfed8d636…`
2020-06-10 20:45 UTC · source 2020-06-10	excluded product	product		`9bebd1f3094a…`	`5416666fcb17…`
2020-06-10 20:45 UTC · source 2020-06-10	excluded package	package	70264-014-01	`9bebd1f3094a…`	`5416666fcb17…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Alka-Seltzer Original
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ASPIRIN	325 mg/1
SODIUM BICARBONATE	1916 mg/1
ANHYDROUS CITRIC ACID	1000 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
R16CO5Y76E	Internal UNII lookup
8MDF5V39QO	Internal UNII lookup
XF417D3PSL	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1536675	Internal RxNorm lookup
1536680	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
dbb0d067-71f0-45e4-bc98-548cf4a90b3a	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
fb7ab793-2c12-4079-b100-a64f73bef25a	Product name	4	20240712
b0cbf770-6cc3-4aa4-9158-755110c2b9f7	Product name	2	20230717
d7724692-1155-4cc8-a415-22f5fc4aec35	Product name	6	20220216
bde672ba-4805-28d0-1986-73543d41b412	Product name	2	20210201
08ffbcbf-26df-b99c-1dab-64fc4cfae89f	Product name	5	20200925
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
419aab54-5d5a-4146-9453-026d4a9991be	Product name	2	20170525
f212291f-05fe-9603-fc7e-bd73e38ce1e6	Product name	2	20161129
ade821ba-260a-47e2-bd89-743e27ac9906	Product name	1	20161121
08ffbcbf-26df-b99c-1dab-64fc4cfae89f	Product name	2	20160823
182f9ab4-4ab5-c449-200f-87ce2ce8e550	Product name	2	20151105
9425d234-4ae1-4b53-adc6-8cc7af6dd657	Product name	1	20150929
2a21311a-89e2-0e83-2ebd-117f9798b2b2	Product name	1	20140508
9007e8a7-ff50-f9b9-7945-f2a1deadd94e	Product name	1	20140508
96c2be53-8e44-452d-56a2-d255b2f1af2d	Product name	1	20140508
bf8bd5f7-495f-4022-2780-7ded7ea7ea44	Product name	1	20140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
70264-014-01	2022-12-26	C162847	48780-1	9d75b9d0-63e5-f424-e053-dadaa90a57ce	Alka-Seltzer ® Original
70264-014-01	2020-01-31	C162847	48780-1	9d75b9d0-63e5-f424-e053-dadaa90a57ce	Alka-Seltzer ® Original

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
70264-014-01	Alka-Seltzer Original	2 in 1 POUCH	TABLET, EFFERVESCENT	2		6
70264-014-01	Alka-Seltzer Original	50 in 1 CARTON	TABLET, EFFERVESCENT	50		6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
70264-014	ALKA-SELTZER ORIGINAL (ANHYDROUS CITRIC ACID, ASPIRIN, AND SODIUM BICARBONATE) TABLET, EFFERVESCENT [R J GENERAL CORPORATION]	5	Current NDC, Legacy NDC, 2 package rows	20241030_dbb0d067-71f0-45e4-bc98-548cf4a90b3a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 33 of 79 · 1,579 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
EXTRA STRENGTH PAIN RELIEVER	ACETAMINOPHEN, ASPIRIN AND CAFFEINE	Geri-Care Pharmaceutical Corp	b670a898-2360-76e2-e053-2a95a90a3380	2025-11-17	Warnings	Exact identifier application number: M013
Pain Reliever PM	ACETAMINOPHEN, DIPHENHYDRAMINE HCL	L.N.K. International, Inc.	ec902e52-0f48-4a61-b67d-17e1c1461619	2025-11-15	Warnings	Exact identifier application number: M013
Pain Reliever Extra Strength	ACETAMINOPHEN	L.N.K. International, Inc.	72babe91-2586-4f05-ae90-6debfd23aa5d	2025-11-15	Warnings	Exact identifier application number: M013
Aspirin Low Dose	ASPIRIN	Strategic Sourcing Services LLC	3c7883da-6f51-4716-b012-0e33d239a60e	2025-11-15	Warnings	Exact identifier application number: M013
Aspirin Low Dose	ASPIRIN	Sam's West Inc	3b84746f-05ab-4f88-b9ae-efb8c5dfc233	2025-11-15	Warnings	Exact identifier application number: M013
Childrens Pain and Fever	ACETAMINOPHEN	Walgreen Company	a482e715-bec0-44a4-bb0e-ea5f5fda558e	2025-11-15	Warnings	Exact identifier application number: M013
Acetaminophen PM Extra Strength	ACETAMINOPHEN, DIPHENHYDRAMINE HCL	ARMY AND AIR FORCE EXCHANGE SERVICE	f1157dbc-d86c-4554-954c-60a74674ff6b	2025-11-15	Warnings	Exact identifier application number: M013
Acetaminophen, Aspirin, Caffeine	ACETAMINOPHEN, ASPIRIN, CAFFEINE	NuCare Pharmaceuticals,Inc.	437e4fd9-c7d9-77d6-e063-6294a90a22b7	2025-11-13	Warnings	Exact identifier application number: M013
Good Sense Pain Relief	ACETAMINOPHEN	L. Perrigo Company	7f78028a-484b-48b3-a37a-1e0b055bbefc	2025-11-13	Warnings	Exact identifier application number: M013
OneSsip Acetaminophen	ACETAMINOPHEN	MEDWISE LIFESCIENCES INC.	3f88de0f-6cf6-3580-e063-6294a90abcb4	2025-11-12	Warnings	Exact identifier application number: M013
Tylenol PM Extra Strength	ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE	Navajo Manufacturing Company Inc.	435b1a31-353d-af20-e063-6294a90aa907	2025-11-11	Warnings	Exact identifier application number: M013
Good Neighbor Pharmacy Pain Relief	ACETAMINOPHEN	Amerisource Bergen	4b829607-f5fb-427f-83b5-5b6b9c44ebeb	2025-11-11	Warnings	Exact identifier application number: M013
Pamprin Max Menstrual Pain Relief	ACETAMINOPHEN AND ASPIRIN AND CAFFEINE	Focus Consumer Healthcare, LLC	5bd4b935-f003-7df8-e053-2a91aa0a5d79	2025-11-10	Warnings	Exact identifier application number: M013
Pain Reliever	ACETAMINOPHEN	Shield Pharmaceuticals Corp	61e50135-a7c2-4a86-8a1a-d47b41d3f9d1	2025-11-07	Warnings	Exact identifier application number: M013
Childrens Chewables	ACETAMINOPHEN	Strategic Sourcing Services LLC	af2cbbaf-9b73-440a-bc88-a790cafccc6b	2025-11-07	Warnings	Exact identifier application number: M013
Aspirin Low Dose	ASPIRIN	L.N.K. International, Inc.	39e142a7-8590-4e1e-8319-6904fb57cc8a	2025-11-06	Warnings	Exact identifier application number: M013
TYLENOL Extra Strength	ACETAMINOPHEN	Kenvue Brands LLC	42321456-d7dd-3b51-e063-6394a90ac292	2025-11-05	Warnings	Exact identifier application number: M013
Childrens Pain Relief	ACETAMINOPHEN	Family Dollar Services Inc	76058eb3-2d3f-4414-87df-7167cd27d26b	2025-11-05	Warnings	Exact identifier application number: M013
Children Pain and Fever Reliver	ACETAMINOPHEN	Target Corporation	1116f808-f61e-47ec-b0d0-d4be5aa905be	2025-11-04	Warnings	Exact identifier application number: M013
Pain Reliever Dye Free	ACETAMINOPHEN	TIME CAP LABORATORIES, INC.	42c4f0b2-6483-0f3c-e063-6294a90a140f	2025-11-04	Warnings	Exact identifier application number: M013

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R16CO5Y76E	ASPIRIN	50-78-2	ASPIRIN
8MDF5V39QO	SODIUM BICARBONATE	144-55-8	SODIUM BICARBONATE
XF417D3PSL	ANHYDROUS CITRIC ACID	77-92-9	ANHYDROUS CITRIC ACID

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1536680	Alka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet	PSN	dbb0d067-71f0-45e4-bc98-548cf4a90b3a	6
1536675	aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet	PSN	dbb0d067-71f0-45e4-bc98-548cf4a90b3a	6
1536680	aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer]	SBD	dbb0d067-71f0-45e4-bc98-548cf4a90b3a	6
1536675	aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet	SCD	dbb0d067-71f0-45e4-bc98-548cf4a90b3a	6
1536680	Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet	SY	dbb0d067-71f0-45e4-bc98-548cf4a90b3a	6
1536675	ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet	SY	dbb0d067-71f0-45e4-bc98-548cf4a90b3a	6
1536680	ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer]	SY	dbb0d067-71f0-45e4-bc98-548cf4a90b3a	6

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
70264-014-01	70264001401	50 POUCH in 1 CARTON (70264-014-01) / 2 TABLET, EFFERVESCENT in 1 POUCH	50 pouch	2010-03-02	0000-00-00	No	No	Current