aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer]

RxCUI
1536680
RxNorm name
aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer]
Display name
ALKA-SELTZER (Effervescent)
Full name
aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer]
Term type
SBD
Status
Active
Strength
325-1,000-1,916 mg
Dose form
Tab
Route
Effervescent
Updated
2026-09-14 22:58:22

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
062014
Active start
062014
Multiple ingredient
YES
Branded
YES

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
aspirin325 MG / 1 EACHaspirinaspirin
citric acid1000 MG / 1 EACHcitric acidcitric acid
sodium bicarbonate1916 MG / 1 EACHsodium bicarbonatesodium bicarbonate

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Effervescent Oral Tablet1535727

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
aspirin1191
citric acid21183
sodium bicarbonate36676

Source Vocabulary Codes#

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
0280-4000-010280-4000Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATEBayer HealthCare LLC.M013
0280-4000-020280-4000Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATEBayer HealthCare LLC.M013
0280-4000-030280-4000Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATEBayer HealthCare LLC.M013
0280-4000-040280-4000Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATEBayer HealthCare LLC.M013
0280-4000-050280-4000Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATEBayer HealthCare LLC.M013
0280-4000-060280-4000Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATEBayer HealthCare LLC.M013
0280-4000-070280-4000Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATEBayer HealthCare LLC.M013
50269-307-0650269-307Alka Seltzer Originial 1s Blister Pack ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATEJC World Bell Wholesale Co., Inc.M013
70264-014-0170264-014Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATER J General CorporationM013
85237-1829-185237-1829Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATESelect Consumer GroupM013

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
M0130280-4000Alka-Seltzer Original ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATEOTC MONOGRAPH DRUGBayer HealthCare LLC.

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 62 matching rows.

NDC11, Source, Active table
NDC11SourceActive
00280400001rxnav_ndcsyes
00280400002rxnav_ndcsyes
00280400003rxnav_ndcsyes
00280400004rxnav_ndcsyes
00280400005rxnav_ndcsyes
00280400006rxnav_ndcsyes
00280400007rxnav_ndcsyes
16500004011rxnav_ndcsyes
16500004012rxnav_ndcsyes
16500004019rxnav_ndcsyes
16500004022rxnav_ndcsyes
16500004030rxnav_ndcsyes
50269030706rxnav_ndcsyes
53666040333rxnav_ndcsyes
70264001401rxnav_ndcsyes
85237182900rxnav_ndcsyes
85237182901rxnav_ndcsyes
85237182902rxnav_ndcsyes
85237182903rxnav_ndcsyes
85237182904rxnav_ndcsyes
85237182906rxnav_ndcsyes
85237182907rxnav_ndcsyes
00280402036rxnav_historical
16500004211rxnav_historical_indirect
16500004212rxnav_historical_indirect
16500004219rxnav_historical_indirect
16500004802rxnav_historical_indirect
16500004806rxnav_historical_indirect
16500004810rxnav_historical_indirect
16500040110rxnav_historical_indirect
16500040120rxnav_historical_indirect
16500040190rxnav_historical_indirect
16500040220rxnav_historical_indirect
16500040240rxnav_historical_indirect
16500042050rxnav_historical_indirect
16500042110rxnav_historical_indirect
16500042120rxnav_historical_indirect
16500042190rxnav_historical_indirect
16500045240rxnav_historical_indirect
16500045300rxnav_historical_indirect
16500048020rxnav_historical_indirect
16500048060rxnav_historical_indirect
16500048100rxnav_historical_indirect
29485650303rxnav_historical
29485753502rxnav_historical
29485753503rxnav_historical
53666010010rxnav_historical_indirect
53666040315rxnav_historical_indirect
54569353300rxnav_historical_indirect
65662000501rxnav_historical
66715510600rxnav_historical
66715970300rxnav_historical
66715970301rxnav_historical
66715970302rxnav_historical
66715970303rxnav_historical
67751014301rxnav_historical
67751014302rxnav_historical
70262030450rxnav_historical
73097000102rxnav_historical
73097000140rxnav_historical
73097000148rxnav_historical
73097000172rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Alka-Seltzer OriginalANHYDROUS CITRIC ACID, ASPIRIN, AND SODIUM BICARBONATESelect Consumer Group3ca80d74-1e8b-49d9-e063-6394a90a43122026-05-24WarningsExact identifier
ndc (package): 85237-1829-1
ndc (product): 85237-1829
ndc11 (package): 85237182907
ndc11 (package): 85237182901
ndc11 (package): 85237182903
ndc11 (package): 85237182906
ndc11 (package): 85237182900
ndc11 (package): 85237182902
ndc11 (package): 85237182904
rxcui: 1536680
Alka-Seltzer OriginalANHYDROUS CITRIC ACID, ASPIRIN, AND SODIUM BICARBONATEBayer HealthCare LLC.5be36a7f-7d1f-468d-9c29-92c8cd3ef1bc2025-12-04WarningsExact identifier
ndc (package): 0280-4000-06
ndc (package): 0280-4000-02
ndc (package): 0280-4000-05
ndc (package): 0280-4000-03
ndc (package): 0280-4000-01
ndc (package): 0280-4000-07
ndc (package): 0280-4000-04
ndc (product): 0280-4000
ndc11 (package): 00280400004
ndc11 (package): 00280400006
ndc11 (package): 00280400007
ndc11 (package): 00280400003
ndc11 (package): 00280400002
ndc11 (package): 00280400001
ndc11 (package): 00280400005
rxcui: 1536680
Alka-Seltzer OriginalANHYDROUS CITRIC ACID, ASPIRIN, AND SODIUM BICARBONATER J General Corporationdbb0d067-71f0-45e4-bc98-548cf4a90b3a2025-11-17WarningsExact identifier
ndc (package): 70264-014-01
ndc (product): 70264-014
ndc11 (package): 70264001401
rxcui: 1536680

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 9 matching rows.

Set ID, RxNorm mappings, Terms table
Set IDRxNorm mappingsTermsSPL versionLabelEffective
5be36a7f-7d1f-468d-9c29-92c8cd3ef1bcAlka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SBD] · Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet [SY] · ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SY]411Alka-Seltzer ® Original20251204
dbb0d067-71f0-45e4-bc98-548cf4a90b3aAlka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SBD] · Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet [SY] · ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SY]46Alka-Seltzer ® Original20251117
8876a416-6a8d-466f-932a-dddf673c32beAlka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SBD] · Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet [SY] · ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SY]43Alka Seltzer Originial 1s Blister Pack20231105
73e85be6-1236-453b-b41c-37381a054773Alka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SBD] · Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet [SY] · ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SY]43Alka Seltzer20121109
4feee16b-43be-bb71-e063-6394a90af959Alka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SBD] · Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet [SY] · ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SY]41SurviveX Travel Med Kit20260507
3ca80d74-1e8b-49d9-e063-6394a90a4312Alka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SBD] · Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet [SY] · ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SY]41Alka-Seltzer ® Original20250818
973da92c-a2d9-e173-e053-2995a90a0455Alka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SBD] · Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet [SY] · ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SY]41Bitterfeld Alka-Seltzer Original20191113
8d334678-2fda-75c5-e053-2a95a90ae344Alka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SBD] · Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet [SY] · ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SY]41Alka Seltzer Original20190708
3b37ab81-2717-4afd-8f66-89a7bed1140eAlka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet [PSN] · aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SBD] · Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet [SY] · ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] [SY]41Alka-Seltzer ® Original20160314

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
3ca80d74-1e8b-49d9-e063-6394a90a4312Alka-Seltzer ® OriginalSelect Consumer Group20260524
5be36a7f-7d1f-468d-9c29-92c8cd3ef1bcAlka-Seltzer ® OriginalBayer HealthCare LLC.20251204
dbb0d067-71f0-45e4-bc98-548cf4a90b3aAlka-Seltzer ® OriginalR J General Corporation20251117
3ca80d74-1e8b-49d9-e063-6394a90a4312Alka-Seltzer ® OriginalSelect Consumer Group20250818
fbfa46b6-1773-4053-b323-66f4321d6472Alka-Seltzer ®Lil' Drug Store Products, Inc20231215
da6b52eb-694a-fa8e-e053-2a95a90aaa18Alka-Seltzer ®Lil' Drug Store Products, Inc.20231214
f05a1c0a-58ef-3810-e053-2a95a90a82ecAlka Seltzer Original FlavorLil' Drug Store Products, Inc.20231206
8876a416-6a8d-466f-932a-dddf673c32beAlka Seltzer Originial 1s Blister PackJC World Bell Wholesale Co., Inc. | Bayer HealthCare LLC20231105
fbf52eee-b307-4640-8f90-909bebe54a42Alka Seltzer OriginalNavajo Manufacturing Company Inc.20230301
973da92c-a2d9-e173-e053-2995a90a0455Bitterfeld Alka-Seltzer OriginalBayer Bitterfeld GMBH20191113
8d334678-2fda-75c5-e053-2a95a90ae344Alka Seltzer OriginalSavings Distributors LLC20190708
3b37ab81-2717-4afd-8f66-89a7bed1140eAlka-Seltzer ® OriginalYour Safety Company20160314
73e85be6-1236-453b-b41c-37381a054773Alka SeltzerSalimex, S.A. | Bayer de Mexico, S.A. de CV20121109

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCA09ABAcid preparationsATC1-4citric acid
ATCB05XAElectrolyte solutionsATC1-4sodium bicarbonate
ATCA01ADOther agents for local oral treatmentATC1-4aspirin
ATCB01ACPlatelet aggregation inhibitors excl. heparinATC1-4aspirin
ATCN02BASalicylic acid and derivativesATC1-4aspirin
ATCB05CBSalt solutionsATC1-4sodium bicarbonate
FDASPLN0000175722Nonsteroidal Anti-inflammatory DrugEPChas_epcaspirin
FDASPLN0000175578Platelet Aggregation InhibitorEPChas_epcaspirin
MEDRTD001241AspirinCHEMhas_ingredientaspirin
MEDRTD019343Citric AcidCHEMhas_ingredientcitric acid
MEDRTD017693Sodium BicarbonateCHEMhas_ingredientsodium bicarbonate
MEDRTD000141Acidosis, Renal TubularDISEASEmay_treatsodium bicarbonate
MEDRTD000141Acidosis, Renal TubularDISEASEmay_treatcitric acid
MEDRTD000224Addison DiseaseDISEASEci_withcitric acid
MEDRTD000471AlkalosisDISEASEci_withsodium bicarbonate
MEDRTD001002AnuriaDISEASEci_withcitric acid
MEDRTD001172Arthritis, RheumatoidDISEASEmay_treataspirin
MEDRTD001778Blood Coagulation DisordersDISEASEci_withaspirin
MEDRTD001791Blood Platelet DisordersDISEASEci_withaspirin
MEDRTD002544Cerebral InfarctionDISEASEmay_preventaspirin
MEDRTD002644ChickenpoxDISEASEci_withaspirin
MEDRTD002675Child, PreschoolDISEASEci_withaspirin
MEDRTD003681DehydrationDISEASEci_withcitric acid
MEDRTD004342Drug HypersensitivityDISEASEci_withsodium bicarbonate
MEDRTD004342Drug HypersensitivityDISEASEci_withaspirin
MEDRTD004342Drug HypersensitivityDISEASEci_withcitric acid
MEDRTD062787Drug OverdoseDISEASEmay_treatsodium bicarbonate
MEDRTD064420Drug-Related Side Effects and Adverse ReactionsDISEASEmay_preventsodium bicarbonate
MEDRTD004415DyspepsiaDISEASEmay_treatsodium bicarbonate
MEDRTD004487EdemaDISEASEci_withsodium bicarbonate
MEDRTD005334FeverDISEASEmay_treataspirin
MEDRTD005764Gastroesophageal RefluxDISEASEmay_treatsodium bicarbonate
MEDRTD006073GoutDISEASEmay_treataspirin
MEDRTD006323Heart ArrestDISEASEmay_treatsodium bicarbonate
MEDRTD006356HeartburnDISEASEmay_treatsodium bicarbonate
MEDRTD006396HematemesisDISEASEci_withaspirin
MEDRTD006474Hemorrhagic DisordersDISEASEci_withaspirin
MEDRTD006947HyperkalemiaDISEASEmay_treatsodium bicarbonate
MEDRTD006947HyperkalemiaDISEASEci_withcitric acid
MEDRTD006955HypernatremiaDISEASEci_withsodium bicarbonate
MEDRTD006996HypocalcemiaDISEASEci_withsodium bicarbonate
MEDRTD007223InfantDISEASEci_withaspirin
MEDRTD007249InflammationDISEASEmay_treataspirin
MEDRTD002546Ischemic Attack, TransientDISEASEmay_preventaspirin
MEDRTD008551MelenaDISEASEci_withaspirin
MEDRTD009203Myocardial InfarctionDISEASEmay_preventaspirin
MEDRTD009298Nasal PolypsDISEASEci_withaspirin
MEDRTD010003OsteoarthritisDISEASEmay_treataspirin
MEDRTD010146PainDISEASEmay_preventaspirin
MEDRTD010146PainDISEASEmay_treataspirin
MEDRTD011225Pre-EclampsiaDISEASEmay_preventaspirin
MEDRTD011263Pregnancy Trimester, ThirdDISEASEci_withaspirin
MEDRTD011654Pulmonary EdemaDISEASEci_withsodium bicarbonate
MEDRTD051437Renal InsufficiencyDISEASEci_withcitric acid
MEDRTD012213Rheumatic FeverDISEASEmay_treataspirin
MEDRTD014555Urination DisordersDISEASEmay_treatcitric acid
MEDRTN0000000226Acid-Base ActivityMOAhas_moasodium bicarbonate
MEDRTN0000000236Alkylating ActivityMOAhas_moacitric acid
MEDRTN0000000160Cyclooxygenase InhibitorsMOAhas_moaaspirin
MEDRTN0000000220Electrolyte ActivityMOAhas_moasodium bicarbonate
MEDRTN0000008831Decreased Platelet Activating Factor ProductionPEhas_peaspirin
MEDRTN0000008832Decreased Platelet AggregationPEhas_peaspirin
MEDRTN0000008836Decreased Prostaglandin ProductionPEhas_peaspirin
MEDRTN0000009006Decreased Thromboxane ProductionPEhas_peaspirin
MEDRTN0000009054Gastric Acid AlterationPEhas_pesodium bicarbonate
MEDRTN0000009549Increased Renal HCO3- ExcretionPEhas_pecitric acid
MEDRTN0000009549Increased Renal HCO3- ExcretionPEhas_pesodium bicarbonate
MEDRTN0000000026Hepatic MetabolismPKhas_pkaspirin
MEDRTN0000000042Renal ExcretionPKhas_pkaspirin

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH325 MG / 1000 MG / 1916 MG
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESSCHEDULE0
NAMESPrescribable SynonymAlka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet
SOURCESSourceGold Standard Alchemy
SOURCESSourceMetathesaurus FDA Structured Product Labels
SOURCESSourceMicromedex RED BOOK
SOURCESSourceMultum MediSource Lexicon