for the temporary relief of: • heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains • upset stomach with headache from overindulgence in food or drink • headache, body aches, and pain alone
fully dissolve 2 tablets in 4 ounces of water before taking adults and children 2 tablets every 4 hours, or as directed by a doctor do not exceed 8 tablets in 24 hours adults 60 years and over 2 tablets every 4 hours, or as directed by a doctor do not exceed 4 tablets in 24 hours children under 12 years consult a doctor
www.alkaseltzer.comAnhydrous citric acid 1000 mg
Aspirin 325 mg (NSAID)*
Sodium bicarbonate (heat-treated) 1916 mg
*nonsteroidal anti-inflammatory drug
Antacid
Analgesic
for the temporary relief of:
• heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains
• upset stomach with headache from overindulgence in food or drink
• headache, body aches, and pain alone
Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness.
Allergy alert: Aspirin may cause a severe allergic reaction which may include: • hives • facial swelling • asthma (wheezing) • shock
Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you
• are age 60 or older
• have had stomach ulcers or bleeding problems
• take a blood thinning (anticoagulant) or steroid drug
• take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)
• have 3 or more alcoholic drinks every day while using this product
• take more or for a longer time than directed
• if you are allergic to aspirin or any other pain reliever/fever reducer
• if you have ever had an allergic reaction to this product or any of its ingredients
• stomach bleeding warning applies to you
• you have a history of stomach problems, such as heartburn
• you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
• you are taking a diuretic
• you have asthma
• you have a sodium-restricted diet
• presently taking a prescription drug (antacids may interact with certain prescription drugs)
• taking a prescription drug for diabetes, gout, or arthritis
do not exceed recommended dosage
• an allergic reaction occurs (seek medical help right away)
• you experience any of the following signs of stomach bleeding
• feel faint • vomit blood • have bloody or black stools
• have stomach pain that does not get better
• symptoms get worse or last more than 10 days
• redness or swelling is present
• ringing in the ears or a loss of hearing occurs
• new symptoms occur
ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
In case of overdose, get medical help or contact a Poison Control Center right away.
fully dissolve 2 tablets in 4 ounces of water before taking
| adults and children | 2 tablets every 4 hours, or as directed by a doctor | do not exceed 8 tablets in 24 hours |
| adults 60 years and over | 2 tablets every 4 hours, or as directed by a doctor | do not exceed 4 tablets in 24 hours |
| children under 12 years | consult a doctor |
• do not use if pouch is opened
• each tablet contains: sodium 567 mg
• store at room temperature. Avoid excessive heat.
• Alka-Seltzer® in water contains principally the antacid sodium citrate and the analgesic sodium acetylsalicylate
Water
1-800-986-0369 (Mon - Fri 9AM - 5PM EST) or www.alkaseltzer.com
| Package NDC | Billing unit | Product NDC | DailyMed indexing SPL | SPL version | Effective |
|---|---|---|---|---|---|
| 0280-4000-01 | EA - Each | 0280-4000 | 32606689-6c79-4060-a9aa-b58911c41835 | 1 | 2018-04-19 |
| 0280-4000-02 | EA - Each | 0280-4000 | 7141eb74-1de3-4c07-882b-ff231c88e678 | 1 | 2017-05-03 |
| 0280-4000-03 | EA - Each | 0280-4000 | 83b8a0a2-63fb-4d7c-bdb3-6bda6370195e | 1 | 2017-05-03 |
| 0280-4000-04 | EA - Each | 0280-4000 | ef6e7000-3638-400e-bf65-9c8c723a2c7d | 1 | 2015-01-05 |
| 0280-4000-07 | EA - Each | 0280-4000 | 3e60255b-47dc-4405-a1c5-3fa19568008b | 1 | 2018-03-08 |
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 67751-143 | 67751-143-01, 67751-143-02 |
| 0280-4000 |
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| WATER | 059QF0KO0R | IACT |
| ANHYDROUS CITRIC ACID | XF417D3PSL | ACTIB |
| ASPIRIN | R16CO5Y76E | ACTIB |
| SODIUM BICARBONATE | 8MDF5V39QO | ACTIB |
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Alka-Seltzer Original | ANHYDROUS CITRIC ACID, ASPIRIN, AND SODIUM BICARBONATE | Bayer HealthCare LLC. | 5be36a7f-7d1f-468d-9c29-92c8cd3ef1bc | 2025-12-04 | Warnings | 0280-4000 |
| f5db5155-47d3-b350-e053-2995a90a1370 | fbf52eee-b307-4640-8f90-909bebe54a42 | 2023-03-01 | Warnings | f5db5155-47d3-b350-e053-2995a90a1370 fbf52eee-b307-4640-8f90-909bebe54a42 |
Adverse event summaries are temporarily unavailable. Other product information remains available.