for the temporary relief of: heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains upset stomach with headache from overindulgence in food or drink headache, body aches, and pain alone
• fully dissolve 2 tablets in 4 ounces of water before taking adults and children 12 years and over 2 tablets every 4 hours, or as directed by a doctor do not exceed 8 tablets in 24 hours adults 60 years and over 2 tablets every 4 hours, or as directed by a doctor do not exceed 4 tablets in 24 hours children under 12 years consult a doctor
www.alkaseltzer.comAnhydrous citric acid 1000 mg
Aspirin 325 mg (NSAID)*
Sodium bicarbonate (heat-treated) 1916 mg
*nonsteroidal anti-inflammatory drug
Antacid
Analgesic
Antacid
for the temporary relief of:
Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness.
Allergy alert: Aspirin may cause a severe allergic reaction which may include: • hives • facial swelling • asthma (wheezing) • shock
Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you
• are age 60 or older
• have had stomach ulcers or bleeding problems
• take a blood thinning (anticoagulant) or steroid drug
• take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)
• have 3 or more alcoholic drinks every day while using this product
• take more or for a longer time than directed
• if you are allergic to aspirin or any other pain reliever/fever reducer
• if you have ever had an allergic reaction to this product or any of its ingredients
• stomach bleeding warning applies to you
• you have a history of stomach problems, such as heartburn
• you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
• you are taking a diuretic
• you have asthma
• you have a sodium-restricted diet
• presently taking a prescription drug (antacids may interact with certain prescription drugs)
• taking a prescription drug for diabetes, gout, or arthritis
do not exceed recommended dosage
• an allergic reaction occurs.Seek medical help right away
• you experience any of the following signs of stomach bleeding
• feel faint • vomit blood • have bloody or black stools • have stomach pain that does not get better
• symptoms get worse or last more than 10 days
• redness or swelling is present
• ringing in the ears or a loss of hearing occurs
• new symptoms occur
ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
In case of overdose, get medical help or contact a Poison Control Center right away.
• fully dissolve 2 tablets in 4 ounces of water before taking
| adults and children 12 years and over | 2 tablets every 4 hours, or as directed by a doctor | do not exceed 8 tablets in 24 hours |
| adults 60 years and over | 2 tablets every 4 hours, or as directed by a doctor | do not exceed 4 tablets in 24 hours |
| children under 12 years | consult a doctor |
•
each tablet contains: sodium 567 mg
• store at room temperature. Avoid excessive heat.
• Alka-Seltzer® in water contains principally the antacid sodium citrate and the analgesic sodium acetylsalicylate
None
1-800-986-0369 (Mon - Fri 9AM - 5PM EST) or www.alkaseltzer.com
| RxCUI | RxNorm string | TTY | SPL version |
|---|---|---|---|
| 1536680 | Alka-Seltzer 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet | PSN | 1 |
| 1536675 | aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet | PSN | 1 |
| 1536680 | aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Alka-Seltzer] | SBD | 1 |
| 1536675 | aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet | SCD | 1 |
| 1536680 | Alka-Seltzer (aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG) Effervescent Oral Tablet | SY | 1 |
| 1536675 | ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet | SY | 1 |
| 1536680 | ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Alka-Seltzer] | SY | 1 |
| Class | Version | Type | Effective |
|---|---|---|---|
| ANHYDROUS CITRIC ACID Pharmacologic Class Indexing | 3 | Indexing - Pharmacologic Class | 20180813 |
| ASPIRIN Pharmacologic Class Indexing | 3 | Indexing - Pharmacologic Class | 20191108 |
| SODIUM CATION Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 73097-001-02 | 2021-01-29 | C162847 | 48780-1 | ba0f9c33-5021-a910-e053-dadaa90a0b85 | Alka Seltzer Original |
| 73097-001-40 | 2021-01-29 | C162847 | 48780-1 | ba0f9c33-5021-a910-e053-dadaa90a0b85 | Alka Seltzer Original |
| 73097-001-48 | 2021-01-29 | C162847 | 48780-1 | ba0f9c33-5021-a910-e053-dadaa90a0b85 | Alka Seltzer Original |
| 73097-001-72 | 2021-01-29 | C162847 | 48780-1 | ba0f9c33-5021-a910-e053-dadaa90a0b85 | Alka Seltzer Original |
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 73097-001-02 | Alka Seltzer Original | 2 in 1 POUCH | TABLET, EFFERVESCENT | 2 | 1 | |
| 73097-001-02 | Alka Seltzer Original | 1 in 1 CARTON | TABLET, EFFERVESCENT | 1 | 1 | |
| 73097-001-40 | Alka Seltzer Original | 20 in 1 CARTON | TABLET, EFFERVESCENT | 20 | 1 | |
| 73097-001-40 | Alka Seltzer Original | 2 in 1 POUCH | TABLET, EFFERVESCENT | 2 | 1 | |
| 73097-001-48 | Alka Seltzer Original | 24 in 1 CARTON | TABLET, EFFERVESCENT | 24 | 1 | |
| 73097-001-48 | Alka Seltzer Original | 2 in 1 POUCH | TABLET, EFFERVESCENT | 2 | 1 | |
| 73097-001-72 | Alka Seltzer Original | 36 in 1 CARTON | TABLET, EFFERVESCENT | 36 | 1 | |
| 73097-001-72 | Alka Seltzer Original | 2 in 1 POUCH | TABLET, EFFERVESCENT | 2 | 1 |
| Package NDC | Billing unit | Product NDC | DailyMed indexing SPL | SPL version | Effective |
|---|---|---|---|---|---|
| 0280-4000-01 | EA - Each | 0280-4000 | 32606689-6c79-4060-a9aa-b58911c41835 | 1 | 2018-04-19 |
| 0280-4000-02 | EA - Each | 0280-4000 | 7141eb74-1de3-4c07-882b-ff231c88e678 | 1 | 2017-05-03 |
| 0280-4000-03 | EA - Each | 0280-4000 | 83b8a0a2-63fb-4d7c-bdb3-6bda6370195e | 1 | 2017-05-03 |
| 0280-4000-04 | EA - Each | 0280-4000 | ef6e7000-3638-400e-bf65-9c8c723a2c7d | 1 | 2015-01-05 |
| 0280-4000-07 | EA - Each | 0280-4000 | 3e60255b-47dc-4405-a1c5-3fa19568008b | 1 | 2018-03-08 |
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 73097-001 | 73097-001-02, 73097-001-40, 73097-001-48, 73097-001-72 |
| 0280-4000 |
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| ANHYDROUS CITRIC ACID | XF417D3PSL | ACTIB |
| ASPIRIN | R16CO5Y76E | ACTIB |
| SODIUM BICARBONATE | 8MDF5V39QO | ACTIB |
| WATER | 059QF0KO0R | IACT |
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Alka-Seltzer Original | ANHYDROUS CITRIC ACID, ASPIRIN, AND SODIUM BICARBONATE | Bayer HealthCare LLC. | 5be36a7f-7d1f-468d-9c29-92c8cd3ef1bc | 2025-12-04 | Warnings | 0280-4000 |
| 8d32fcd8-4ae6-1c8d-e053-2a95a90ad4c7 | 8d334678-2fda-75c5-e053-2a95a90ae344 | 2019-07-08 | Warnings | 8d32fcd8-4ae6-1c8d-e053-2a95a90ad4c7 8d334678-2fda-75c5-e053-2a95a90ae344 |
Adverse event summaries are temporarily unavailable. Other product information remains available.