Ramelteon

Product NDC
70518-4257
11-digit product format
705184257
Labeler code
70518
Product ID
70518-4257_4008bca7-b73b-5d1c-e063-6394a90a179b
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Ramelteon
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
REMEDYREPACK INC.
Application
ANDA213815
Marketing category
ANDA
Marketing start
2025-01-20
Substance
RAMELTEON
Active strength
8 mg/1
Pharmacologic classes
Melatonin Receptor Agonist [EPC], Melatonin Receptor Agonists [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A213815-001RAMELTEONRAMELTEON8MGTABLET / ORALAB2020-10-26

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A213815-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-265c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-265d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-264b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-2687673890dc5c…
2021-03-12 10:30 UTC2021-03A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-265aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-268869cabd3fbd…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-266a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-261c564ffb4f44…
2023-12-20 04:57 UTC2023-12A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-269b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-263f0d92c62455…
2023-05-13 08:27 UTC2023-05A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26053a50430f4f…
2023-01-26 05:58 UTC2023-01A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-263bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-263a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A213815-001RAMELTEON8MGTABLET / ORALAB2020-10-26a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A213815-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213815-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A213815-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213815-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213815-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213815-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213815-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213815-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213815-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213815-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213815-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213815-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213815-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A213815-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A213815-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A213815-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A213815-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A213815-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A213815-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A213815-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A213815-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A213815-001AB18869cabd3fbd…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A213815-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A213815-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A213815-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A213815-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A213815-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A213815-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A213815-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A213815-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A213815-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A213815-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A213815-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A213815-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A213815-001AB1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A213815-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Ramelteon
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
RAMELTEON8 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
901AS54I69Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
577348Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
5a3cf917-3569-4fc1-8b81-ffecfd2de005Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
3a82c83c-9d80-697e-efb4-23e95bcb1bc2Product name820240809

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
70518-4257-0Ramelteon30 in 1 BOTTLE, PLASTICTABLET, FILM COATED302

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
70518-4257RAMELTEON TABLET, FILM COATED [REMEDYREPACK INC.]1Current NDC, 1 package rows20250121_5a3cf917-3569-4fc1-8b81-ffecfd2de005.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 5 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
RamelteonRAMELTEONBryant Ranch Prepack86296f99-efef-4cbb-84cb-097b2edcfe9c2026-03-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213815
application number: ANDA213815
RamelteonRAMELTEONUpsher-Smith Laboratories, LLC2d22e6ae-2373-4a2f-8dda-d223230c60102026-01-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213815
application number: ANDA213815
RamelteonRAMELTEONREMEDYREPACK INC.5a3cf917-3569-4fc1-8b81-ffecfd2de0052025-09-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213815
application number: ANDA213815
ndc (product): 70518-4257
RamelteonRAMELTEONDirect_Rxfd169dd8-70a0-b6b4-e053-6394a90a3a6f2025-01-22Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213815
application number: ANDA213815
RamelteonRAMELTEONAdvanced Rx Pharmacy of Tennessee, LLCfe2fc3b7-4600-c14e-e053-6394a90a25862024-12-31Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213815
application number: ANDA213815

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
577348ramelteon 8 MG Oral TabletPSN5a3cf917-3569-4fc1-8b81-ffecfd2de0052
577348ramelteon 8 MG Oral TabletSCD5a3cf917-3569-4fc1-8b81-ffecfd2de0052

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
70518-4257-07051842570030 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (70518-4257-0) 2025-01-20NoNoCurrent