Valproic Acid

Product NDC
70518-4298
11-digit product format
705184298
Labeler code
70518
Product ID
70518-4298_401e1843-e96b-fda9-e063-6294a90a3073
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Valproic Acid
Dosage form
SOLUTION
Route
ORAL
Labeler
REMEDYREPACK INC.
Application
ANDA073178
Marketing category
ANDA
Marketing start
2025-02-27
Substance
VALPROIC ACID
Active strength
250 mg/5mL
Pharmacologic classes
Anti-epileptic Agent [EPC], Decreased Central Nervous System Disorganized Electrical Activity [PE], Mood Stabilizer [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A073178-001VALPROIC ACIDVALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A073178-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-2587673890dc5c…
2021-03-12 10:30 UTC2021-03A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-255aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-258869cabd3fbd…
2020-11-12 02:37 UTC2020-11A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25c0c555d07b60…
2019-12-14 00:12 UTC2019-12A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-253f01610625f2…
2019-09-15 20:21 UTC2019-09A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-25b00525d2431f…
2019-07-19 19:46 UTC2019-07A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-25ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A073178-001VALPROIC ACID250MG/5MLSYRUP / ORALAA1992-08-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-259b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-253f0d92c62455…
2023-05-13 08:27 UTC2023-05A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25053a50430f4f…
2023-01-26 05:58 UTC2023-01A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-253bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-253a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A073178-001VALPROIC ACID250MG/5MLSYRUP / ORAL1992-08-25cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A073178-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A073178-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A073178-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A073178-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A073178-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A073178-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A073178-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A073178-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A073178-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A073178-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A073178-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A073178-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A073178-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A073178-001AA18072bd15b7f6…
2019-12-13 00:20 UTC2019-12A073178-001AA174a2ff9319b5…
2019-12-14 00:12 UTC2019-12A073178-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A073178-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A073178-001AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A073178-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A073178-001AA11c564ffb4f44…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A073178-001AA1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Valproic Acid
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
VALPROIC ACID250 mg/5mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
614OI1Z5WIInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1099687Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1edd220d-d151-4177-9a29-9fee36489fb7Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b10a892b-b985-4cbc-9547-9ac4b72b784fProduct name220250818
7a3a03f1-382a-f9ec-0741-ff24dcbfed69Product name720250624
57fc3d01-4737-4091-9728-9e8a4c9e708dProduct name120200121
5d67ecc7-47c7-ec5e-e9eb-71bf00250645Product name120140508
97fce1a8-50c4-f088-0e31-64d82b6e9081Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
70518-4298-0Valproic Acid10 in 1 BOXSOLUTION103
70518-4298-1Valproic Acid20 mL in 1 CUPSOLUTION203
70518-4298-2Valproic Acid10 in 1 BOXSOLUTION103
70518-4298-3Valproic Acid10 mL in 1 CUPSOLUTION103
70518-4298-4Valproic Acid10 in 1 BOXSOLUTION103
70518-4298-5Valproic Acid5 mL in 1 CUPSOLUTION53

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
70518-4298VALPROIC ACID SOLUTION [REMEDYREPACK INC.]2Current NDC, 6 package rows20250327_1edd220d-d151-4177-9a29-9fee36489fb7.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Valproic AcidVALPROIC ACIDANI Pharmaceuticals, Inc.2314af65-b928-42a9-91eb-6372909ab4f52026-03-31Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 073178
application number: ANDA073178
Valproic AcidVALPROIC ACIDREMEDYREPACK INC.1edd220d-d151-4177-9a29-9fee36489fb72025-10-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 073178
application number: ANDA073178
ndc (product): 70518-4298
Valproic AcidVALPROIC ACIDKesin Pharma Corporation3a2155d0-e79d-3e11-e063-6294a90a4aae2025-07-17Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 073178
application number: ANDA073178
Valproic AcidVALPROIC ACIDNorthStar Rx LLC1286ab49-fa34-488e-e063-6394a90ad5822024-05-27Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 073178
application number: ANDA073178

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1099687valproic acid 250 MG in 5 mL Oral SolutionPSN1edd220d-d151-4177-9a29-9fee36489fb73
1099687valproic acid 50 MG/ML Oral SolutionSCD1edd220d-d151-4177-9a29-9fee36489fb73
1099687valproate sodium 50 MG/ML SyrupSY1edd220d-d151-4177-9a29-9fee36489fb73
1099687valproic acid 250 MG per 5 ML Oral SolutionSY1edd220d-d151-4177-9a29-9fee36489fb73
1099687valproic acid 500 MG per 10 ML Oral SolutionSY1edd220d-d151-4177-9a29-9fee36489fb73
1099687VPA 50 MG/ML Oral SolutionSY1edd220d-d151-4177-9a29-9fee36489fb73

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
70518-4298-07051842980010 CUP in 1 BOX (70518-4298-0) / 20 mL in 1 CUP (70518-4298-1) 10 cup2025-02-27NoNoCurrent
70518-4298-17051842980120 mL in 1 CUP20 mlHistorical
70518-4298-27051842980210 CUP in 1 BOX (70518-4298-2) / 10 mL in 1 CUP (70518-4298-3) 10 cup2025-02-27NoNoCurrent
70518-4298-37051842980310 mL in 1 CUP10 mlHistorical
70518-4298-47051842980410 CUP in 1 BOX (70518-4298-4) / 5 mL in 1 CUP (70518-4298-5) 10 cup2025-02-27NoNoCurrent
70518-4298-5705184298055 mL in 1 CUP5 mlHistorical