Ephedrine Sulfate

Product NDC
70700-249
11-digit product format
707000249
Labeler code
70700
Product ID
70700-249_d3361dc6-a75e-ad9e-74fb-50965204eca3
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Ephedrine Sulfate
Dosage form
INJECTION
Route
INTRAVENOUS
Labeler
Xiromed, LLC
Application
ANDA215825
Marketing category
ANDA
Marketing start
2022-04-21
Substance
EPHEDRINE SULFATE
Active strength
50 mg/mL
Pharmacologic classes
Adrenergic alpha-Agonists [MoA], Adrenergic beta-Agonists [MoA], Increased Norepinephrine Activity [PE], Norepinephrine Releasing Agent [EPC], alpha-Adrenergic Agonist [EPC], beta-Adrenergic Agonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A215825-001EPHEDRINE SULFATEEPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A215825-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-211e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-218072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-215c6f7cd8ea54…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-216a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-211c564ffb4f44…
2023-12-20 04:57 UTC2023-12A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-219b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-213f0d92c62455…
2023-05-13 08:27 UTC2023-05A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21053a50430f4f…
2023-01-26 05:58 UTC2023-01A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-213bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-213a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215825-001EPHEDRINE SULFATE50MG/ML (50MG/ML)SOLUTION / INTRAVENOUSAP2022-04-21a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A215825-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215825-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A215825-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215825-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215825-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215825-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215825-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215825-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215825-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215825-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215825-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215825-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215825-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215825-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A215825-001AP15c6f7cd8ea54…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215825-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A215825-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A215825-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A215825-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A215825-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A215825-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A215825-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A215825-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A215825-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A215825-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A215825-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A215825-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A215825-001AP1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215825-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Ephedrine Sulfate
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
EPHEDRINE SULFATE50 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
U6X61U5ZEGInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1116294Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8302176c-d443-97f1-1a49-12b9a204121aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d1bd959e-e326-44fb-b8ca-8c56a84a2a3dProduct name220251211
f1d178e1-1663-4c63-ae37-62a1b322fba4Product name220251106
f606d3ac-dd63-4b29-bea0-db23753b8ddcProduct name120220118
48747306-602a-42cc-957b-5b0c69158eeeProduct name120180604
30254138-2d98-4aa2-8e07-ae82e8b0a389Product name320171103
fee762de-ffd9-404d-8bc6-8c0c208e758dProduct name120170426
db5ebcdb-b6ae-21cd-4dc5-76cd84b5578bProduct name120140508

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
70700-249-23ML - Milliliter70700-249460ec50d-74ba-430a-a4ce-73cd6876eb0712023-08-08
70700-249-25ML - Milliliter70700-24921c90a57-2206-41b7-bb00-291ba97023b912023-08-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
70700-249EPHEDRINE SULFATE INJECTION [XIROMED, LLC]1Current NDC20230413_8302176c-d443-97f1-1a49-12b9a204121a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Ephedrine SulfateEPHEDRINE SULFATEMedical Purchasing Solutions, LLC296b3b1f-a151-fd40-e063-6294a90a4f4e2024-12-16Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215825
application number: ANDA215825
Ephedrine SulfateEPHEDRINE SULFATEXiromed, LLC8302176c-d443-97f1-1a49-12b9a204121a2023-04-11Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215825
application number: ANDA215825
ndc (product): 70700-249

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1116294ePHEDrine sulfate 50 MG in 1 ML InjectionPSN296b3b1f-a151-fd40-e063-6294a90a4f4e2
11162941 ML ephedrine sulfate 50 MG/ML InjectionSCD296b3b1f-a151-fd40-e063-6294a90a4f4e2
1116294ephedrine sulfate 50 MG per 1 ML InjectionSY296b3b1f-a151-fd40-e063-6294a90a4f4e2
1116294ePHEDrine sulfate 50 MG in 1 ML InjectionPSN8302176c-d443-97f1-1a49-12b9a204121a1
11162941 ML ephedrine sulfate 50 MG/ML InjectionSCD8302176c-d443-97f1-1a49-12b9a204121a1
1116294ephedrine sulfate 50 MG per 1 ML InjectionSY8302176c-d443-97f1-1a49-12b9a204121a1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
70700-249-237070002492310 VIAL, SINGLE-DOSE in 1 CARTON (70700-249-23) / 1 mL in 1 VIAL, SINGLE-DOSE2023-04-11NoNoCurrent
70700-249-257070002492525 VIAL, SINGLE-DOSE in 1 CARTON (70700-249-25) / 1 mL in 1 VIAL, SINGLE-DOSE2023-04-11NoNoCurrent