BUMETANIDE

Product NDC
70748-323
11-digit product format
707480323
Labeler code
70748
Product ID
70748-323_39d376d9-2fab-40d3-8592-668c5083a0c9
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Bumetanide
Dosage form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Labeler
Lupin Pharmaceuticals, Inc.
Application
ANDA217153
Marketing category
ANDA
Marketing start
2024-11-11
Substance
BUMETANIDE
Active strength
.25 mg/mL
Pharmacologic classes
Increased Diuresis at Loop of Henle [PE], Loop Diuretic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217153-001BUMETANIDEBUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-17

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A217153-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-172680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-17d06236e962d9…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217153-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2024-09-17a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A217153-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217153-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217153-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217153-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217153-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217153-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217153-001AP12680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217153-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A217153-001AP1d06236e962d9…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217153-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
BUMETANIDE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BUMETANIDE.25 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
0Y2S3XUQ5HInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
282486Internal RxNorm lookup
1727569Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2c71a17e-ed76-4545-b23e-9f4997b13c2fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1d3f2f0a-cce7-32fe-77bf-6ee61839e736Product name920260113
601d9750-f415-d9d9-619c-0a87b4d3f237Product name320250331
1d3f2f0a-cce7-32fe-77bf-6ee61839e736Product name220171211
9869efd7-d6dd-0665-5b67-53adbe6ef15eProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
70748-323-10BUMETANIDE4 mL in 1 VIALINJECTION46
70748-323-10BUMETANIDE10 in 1 CARTONINJECTION106
70748-323-11BUMETANIDE10 in 1 CARTONINJECTION106
70748-323-11BUMETANIDE10 mL in 1 VIALINJECTION106

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
70748-323-10ML - Milliliter70748-323a37fae7c-f096-4aee-aeab-af8850daad7912024-12-10
70748-323-11ML - Milliliter70748-323e583559f-8ec0-4195-8506-e85308b5334212024-12-10

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
70748-323BUMETANIDE INJECTION [LUPIN PHARMACEUTICALS, INC.]5Current NDC, 4 package rows20250418_2c71a17e-ed76-4545-b23e-9f4997b13c2f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
BUMETANIDEBUMETANIDELupin Pharmaceuticals, Inc.2c71a17e-ed76-4545-b23e-9f4997b13c2f2025-11-25Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217153
application number: ANDA217153
ndc (product): 70748-323

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
282486bumetanide 0.25 MG/ML Injectable SolutionPSN2c71a17e-ed76-4545-b23e-9f4997b13c2f6
1727569bumetanide 1 MG in 4 ML InjectionPSN2c71a17e-ed76-4545-b23e-9f4997b13c2f6
17275694 ML bumetanide 0.25 MG/ML InjectionSCD2c71a17e-ed76-4545-b23e-9f4997b13c2f6
282486bumetanide 0.25 MG/ML Injectable SolutionSCD2c71a17e-ed76-4545-b23e-9f4997b13c2f6
1727569bumetanide 1 MG per 4 ML InjectionSY2c71a17e-ed76-4545-b23e-9f4997b13c2f6

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
70748-323-107074803231010 VIAL in 1 CARTON (70748-323-10) / 4 mL in 1 VIAL10 vial2024-11-11NoNoCurrent
70748-323-117074803231110 VIAL in 1 CARTON (70748-323-11) / 10 mL in 1 VIAL10 vial2024-11-11NoNoCurrent