Lubiprostone

Product NDC
70771-1764
11-digit product format
707711764
Labeler code
70771
Product ID
70771-1764_570c527a-5ee5-4950-b27a-48f652af549f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Lubiprostone
Dosage form
CAPSULE
Route
ORAL
Labeler
Zydus Lifesciences Limited
Application
ANDA214131
Marketing category
ANDA
Marketing start
2023-03-23
Substance
LUBIPROSTONE
Active strength
24 ug/1
Pharmacologic classes
Chloride Channel Activator [EPC], Chloride Channel Activators [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A214131-001LUBIPROSTONELUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23
A214131-002LUBIPROSTONELUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A214131-001AB
A214131-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 48 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23caaa826d4ba7…
2026-08-18 06:07:402026-07A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-2303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-2303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-232680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-232680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-235bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-235bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23d06236e962d9…
2024-10-29 15:01 UTC2024-10A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-2379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-2379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-231e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-231e350fbaab3a…
2024-05-31 18:47 UTC2024-05A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-238072bd15b7f6…
2024-05-31 18:47 UTC2024-05A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-238072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-236a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-236a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-231c564ffb4f44…
2024-02-18 07:12 UTC2024-02A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-231c564ffb4f44…
2023-12-20 04:57 UTC2023-12A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-23a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-23a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A214131-001LUBIPROSTONE8MCGCAPSULE / ORALAB2023-03-239b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A214131-002LUBIPROSTONE24MCGCAPSULE / ORALAB2023-03-239b2671bbb829…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 48 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A214131-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A214131-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A214131-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A214131-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214131-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214131-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A214131-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A214131-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214131-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214131-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214131-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214131-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214131-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214131-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214131-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214131-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214131-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214131-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214131-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214131-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A214131-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A214131-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214131-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214131-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214131-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214131-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214131-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214131-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A214131-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A214131-002AB18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214131-001AB16a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214131-002AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A214131-001AB11c564ffb4f44…
2024-02-18 07:12 UTC2024-02A214131-002AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A214131-001AB1ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A214131-002AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214131-001AB1a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214131-002AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A214131-001AB19b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A214131-002AB19b2671bbb829…

Additional Listing Data#

Finished product
Yes
Brand name base
Lubiprostone
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LUBIPROSTONE24 ug/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7662KG2R6KInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
616578Internal RxNorm lookup
794639Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
81f9c9de-f89d-4ab0-a8ca-18d3691e42f9Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
3b517f14-6449-952f-8aaf-98f2ec9051d0Product name320251024

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
70771-1764-1Lubiprostone100 in 1 BOTTLECAPSULE1002
70771-1764-6Lubiprostone60 in 1 BOTTLECAPSULE602

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
70771-1764LUBIPROSTONE CAPSULE [ZYDUS LIFESCIENCES LIMITED]2Current NDC, 2 package rows20241204_81f9c9de-f89d-4ab0-a8ca-18d3691e42f9.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
LubiprostoneLUBIPROSTONEAsclemed USA, Inc.5797e57c-4e87-48d9-b16d-992f64db594f2025-02-06Warnings, Adverse reactionsExact identifier
application applno (ANDA): 214131
application number: ANDA214131
LubiprostoneLUBIPROSTONEZydus Lifesciences Limited81f9c9de-f89d-4ab0-a8ca-18d3691e42f92024-11-30Exact identifier
application applno (ANDA): 214131
application number: ANDA214131
ndc (product): 70771-1764
LubiprostoneLUBIPROSTONEZydus Pharmaceuticals USA Inc.6c11a204-6831-4269-a3c4-1702ed83f74b2023-03-27Warnings, Adverse reactionsExact identifier
application applno (ANDA): 214131
application number: ANDA214131

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
616578lubiprostone 24 MCG Oral CapsulePSN81f9c9de-f89d-4ab0-a8ca-18d3691e42f92
794639lubiprostone 8 MCG Oral CapsulePSN81f9c9de-f89d-4ab0-a8ca-18d3691e42f92
794639lubiprostone 0.008 MG Oral CapsuleSCD81f9c9de-f89d-4ab0-a8ca-18d3691e42f92
616578lubiprostone 0.024 MG Oral CapsuleSCD81f9c9de-f89d-4ab0-a8ca-18d3691e42f92
616578lubiprostone 24 MCG Oral CapsuleSY81f9c9de-f89d-4ab0-a8ca-18d3691e42f92
794639lubiprostone 8 MCG Oral CapsuleSY81f9c9de-f89d-4ab0-a8ca-18d3691e42f92

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
70771-1764-170771176401100 CAPSULE in 1 BOTTLE (70771-1764-1) 100 capsule2023-03-23NoNoCurrent
70771-1764-67077117640660 CAPSULE in 1 BOTTLE (70771-1764-6) 60 capsule2023-03-23NoNoCurrent