Tosymra

Product NDC
70792-812
11-digit product format
707920812
Labeler code
70792
Product ID
70792-812_803144a8-2d17-47ac-98d0-515198ba722d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Sumatriptan
Dosage form
SPRAY
Route
NASAL
Labeler
Tonix Medicines, Inc.
Application
NDA210884
Marketing category
NDA
Marketing start
2023-07-01
Substance
SUMATRIPTAN
Active strength
10 mg/.1mL
Pharmacologic classes
Serotonin 1b Receptor Agonists [MoA], Serotonin 1d Receptor Agonists [MoA], Serotonin-1b and Serotonin-1d Receptor Agonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N210884-001TOSYMRASUMATRIPTAN10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25

Orange Book patents#

Current patent rows page 1 of 1 · 9 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N210884-00182687912026-05-09Drug product2019-02-21
N210884-00184406312026-05-09U-1719Drug product2019-02-21
N210884-00192832802026-05-09Drug product2019-02-21
N210884-001106033052030-06-16U-1719Drug product2020-03-31
N210884-001113379622030-06-16U-1719Drug product2022-05-25
N210884-001120901392030-06-16Drug product2024-10-17
N210884-00196102802030-06-16U-1719Drug product2019-02-21
N210884-00199747702030-06-16U-1719Drug product2019-02-21
N210884-00192112822031-07-19U-1719Drug product2019-02-21

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-2587673890dc5c…
2021-03-12 10:30 UTC2021-03N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-255aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-258869cabd3fbd…
2020-11-12 02:37 UTC2020-11N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25c0c555d07b60…
2019-12-14 00:12 UTC2019-12N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-253f01610625f2…
2019-09-15 20:21 UTC2019-09N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25b00525d2431f…
2019-07-19 19:46 UTC2019-07N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-259b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-253f0d92c62455…
2023-05-13 08:27 UTC2023-05N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25053a50430f4f…
2023-01-26 05:58 UTC2023-01N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-253bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-253a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N210884-001TOSYMRA10MG/SPRAYSPRAY / NASALRLD, RS2019-01-25e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 9 · 330 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N210884-00182687912026-05-09Drug product2019-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N210884-00184406312026-05-09U-1719Drug product2019-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N210884-00192832802026-05-09Drug product2019-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N210884-001106033052030-06-16U-1719Drug product2020-03-31caaa826d4ba7…
2026-08-18 06:07:402026-07N210884-001113379622030-06-16U-1719Drug product2022-05-25caaa826d4ba7…
2026-08-18 06:07:402026-07N210884-001120901392030-06-16Drug product2024-10-17caaa826d4ba7…
2026-08-18 06:07:402026-07N210884-00196102802030-06-16U-1719Drug product2019-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N210884-00199747702030-06-16U-1719Drug product2019-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N210884-00192112822031-07-19U-1719Drug product2019-02-21caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210884-00182687912026-05-09Drug product2019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210884-00184406312026-05-09U-1719Drug product2019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210884-00192832802026-05-09Drug product2019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210884-001106033052030-06-16U-1719Drug product2020-03-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210884-001113379622030-06-16U-1719Drug product2022-05-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210884-001120901392030-06-16Drug product2024-10-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210884-00196102802030-06-16U-1719Drug product2019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210884-00199747702030-06-16U-1719Drug product2019-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210884-00192112822031-07-19U-1719Drug product2019-02-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-00182687912026-05-09Drug product2019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-00184406312026-05-09U-1719Drug product2019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-00192832802026-05-09Drug product2019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-001106033052030-06-16U-1719Drug product2020-03-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-001113379622030-06-16U-1719Drug product2022-05-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-001120901392030-06-16Drug product2024-10-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-00196102802030-06-16U-1719Drug product2019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-00199747702030-06-16U-1719Drug product2019-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210884-00192112822031-07-19U-1719Drug product2019-02-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08N210884-00182687912026-05-09Drug product2019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210884-00184406312026-05-09U-1719Drug product2019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210884-00192832802026-05-09Drug product2019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210884-001106033052030-06-16U-1719Drug product2020-03-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210884-001113379622030-06-16U-1719Drug product2022-05-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210884-001120901392030-06-16Drug product2024-10-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210884-00196102802030-06-16U-1719Drug product2019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210884-00199747702030-06-16U-1719Drug product2019-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210884-00192112822031-07-19U-1719Drug product2019-02-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210884-00182687912026-05-09Drug product2019-02-21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210884-00184406312026-05-09U-1719Drug product2019-02-21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210884-00192832802026-05-09Drug product2019-02-21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210884-001106033052030-06-16U-1719Drug product2020-03-31fd3edfee7708…

Additional Listing Data#

Finished product
Yes
Brand name base
Tosymra
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
SUMATRIPTAN10 mg/.1mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8R78F6L9VOInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
401978Internal RxNorm lookup
2178073Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
d9f682f0-d50a-4fe6-ab1b-e5a7ec27b3a5Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
59adc2ba-d5f0-4a52-b35a-cc77921a79d2Product name420250724
efd58dcf-540a-4531-8766-e713129ca6f2Product name120250307
726062af-1135-4707-a1d7-57256991bbf9Product name220250226
2839c963-7eb3-970a-287f-ff1b6d381268Product name220250103
1e973b2d-e028-69cd-9258-4613ba80fdc5Product name320210512
3eb481d3-8b69-436f-82dd-4a66345568abProduct name120190611
e76dbbc1-775d-722c-08ff-ed45e8a80defProduct name320181002
c100f0c7-e9dd-42f4-b0a8-0d81bd2a877cProduct name120160303
49615343-b619-4365-8118-8f2ed6046e78Product name120160224
a6319377-430a-43db-82f9-30d1d9d89cf8Product name120151216
19c71a3d-ed9c-166b-a7e5-38c250c35631Product name120140508
f6199b09-e585-7ceb-4b09-803cf5ce1ed1Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
70792-812-59Tosymra1 in 1 CARTONSPRAY13
70792-812-59Tosymra1 in 1 BLISTER PACKSPRAY13
70792-812-61Tosymra6 in 1 CARTONSPRAY63
70792-812-61Tosymra1 in 1 BLISTER PACKSPRAY13
70792-812-89Tosymra1 in 1 BLISTER PACKSPRAY13
70792-812-89Tosymra1 in 1 CARTONSPRAY13

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
70792-812-61EA - Each70792-8126fe85c7b-1439-488e-aa0a-a07631faf9a812025-05-14
70792-812-89EA - Each70792-812dc737879-a677-4c7b-addc-d7210be01c1e12025-05-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
70792-812TOSYMRA (SUMATRIPTAN) SPRAY [TONIX MEDICINES, INC.]3Current NDC, 6 package rows20250309_d9f682f0-d50a-4fe6-ab1b-e5a7ec27b3a5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TosymraSUMATRIPTANTonix Medicines, Inc.d9f682f0-d50a-4fe6-ab1b-e5a7ec27b3a52025-02-21Warnings, Adverse reactionsExact identifier
application applno (NDA): 210884
application number: NDA210884
ndc (product): 70792-812
TOSYMRASUMATRIPTANUpsher-Smith Laboratories, LLC015a5cf9-f246-48bc-b91e-cd730a53d8aa2024-11-18Warnings, Adverse reactionsExact identifier
application applno (NDA): 210884
application number: NDA210884

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
401978SUMAtriptan 10 MG/ACTUAT Nasal SprayPSNd9f682f0-d50a-4fe6-ab1b-e5a7ec27b3a53
2178073tosymra 10 MG in 0.1 mL Nasal SprayPSNd9f682f0-d50a-4fe6-ab1b-e5a7ec27b3a53
2178073sumatriptan 10 MG/ACTUAT Nasal Spray [Tosymra]SBDd9f682f0-d50a-4fe6-ab1b-e5a7ec27b3a53
401978sumatriptan 10 MG/ACTUAT Nasal SpraySCDd9f682f0-d50a-4fe6-ab1b-e5a7ec27b3a53
401978sumatriptan 10 MG/Spray Nasal SpraySYd9f682f0-d50a-4fe6-ab1b-e5a7ec27b3a53
2178073Tosymra 10 MG/ACTUAT Nasal SpraySYd9f682f0-d50a-4fe6-ab1b-e5a7ec27b3a53

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
70792-812-59707920812591 BLISTER PACK in 1 CARTON (70792-812-59) / 1 BOTTLE, SPRAY in 1 BLISTER PACK / .1 mL in 1 BOTTLE, SPRAY1 blister pack2024-07-01YesNoCurrent
70792-812-61707920812616 BLISTER PACK in 1 CARTON (70792-812-61) / 1 BOTTLE, SPRAY in 1 BLISTER PACK / .1 mL in 1 BOTTLE, SPRAY6 blister pack2024-07-01NoNoCurrent
70792-812-89707920812891 BLISTER PACK in 1 CARTON (70792-812-89) / 1 BOTTLE, SPRAY in 1 BLISTER PACK / .1 mL in 1 BOTTLE, SPRAY1 blister pack2025-04-01NoNoCurrent