Bisoprolol Fumarate

Product NDC
70954-456
11-digit product format
709540456
Labeler code
70954
Product ID
70954-456_6517d564-ea55-4084-a8ab-34fea548c24e
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Bisoprolol Fumarate
Dosage form
TABLET
Route
ORAL
Labeler
Novitium Pharma LLC
Application
ANDA215563
Marketing category
ANDA
Marketing start
2021-10-29
Substance
BISOPROLOL FUMARATE
Active strength
10 mg/1
Pharmacologic classes
Adrenergic beta-Antagonists [MoA], beta-Adrenergic Blocker [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A215563-001BISOPROLOL FUMARATEBISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-29
A215563-002BISOPROLOL FUMARATEBISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-29

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A215563-001AB
A215563-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 66 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-29011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-2931067a03dcf5…
2025-08-23 18:47 UTC2025-08A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-296a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-29fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-29fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-29b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-29b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-2903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-2903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-292680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-292680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-295bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-295bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-29d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-29d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-29d06236e962d9…
2024-10-29 15:01 UTC2024-10A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-29d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-2979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-2979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-29301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-29301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-291e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-291e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-298072bd15b7f6…
2024-05-31 18:47 UTC2024-05A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-298072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-295c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-295c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-295d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-295d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-294b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-294b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-29bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-29bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-29782e0a99824c…
2021-12-28 21:50 UTC2021-12A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-29782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215563-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2021-10-296a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215563-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2021-10-296a51e52b5d6a…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 66 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A215563-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A215563-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215563-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215563-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A215563-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A215563-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215563-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215563-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215563-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215563-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215563-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215563-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215563-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215563-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215563-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215563-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215563-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215563-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215563-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A215563-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215563-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215563-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215563-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215563-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215563-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215563-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215563-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A215563-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A215563-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A215563-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A215563-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A215563-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A215563-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A215563-002AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A215563-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A215563-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A215563-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A215563-002AB1782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215563-001AB16a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215563-002AB16a51e52b5d6a…

Additional Listing Data#

Finished product
Yes
Brand name base
Bisoprolol Fumarate
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BISOPROLOL FUMARATE10 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
UR59KN573LInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
854901Internal RxNorm lookup
854905Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6517d564-ea55-4084-a8ab-34fea548c24eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
97e4a60d-917d-ef62-dc8a-bd557b62b708Product name720260129
9b303cd4-3186-2454-5706-3137e8b2dfd2Product name420221110

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
70954-456-10Bisoprolol Fumarate30 in 1 BOTTLETABLET301
70954-456-20Bisoprolol Fumarate100 in 1 BOTTLETABLET1001

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
70954-456-10EA - Each70954-45602c24293-f8a1-45bf-a364-9d5f29ad1ac112022-01-06
70954-456-20EA - Each70954-456a9ba38c5-a955-4c83-9b4c-e6764790777312022-01-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
70954-456BISOPROLOL FUMARATE TABLET [NOVITIUM PHARMA LLC]1Current NDC, Legacy NDC, 2 package rows20211106_6517d564-ea55-4084-a8ab-34fea548c24e.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Bisoprolol FumarateBISOPROLOL FUMARATEGolden State Medical Supply, Inc.df37d337-9978-0c31-e053-2a95a90a32582026-04-21Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215563
application number: ANDA215563
Bisoprolol FumarateBISOPROLOL FUMARATEBryant Ranch Prepackf6ce8f14-43fc-4c5e-8378-62ca7121e9182023-11-17Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215563
application number: ANDA215563
Bisoprolol FumarateBISOPROLOL FUMARATENovitium Pharma LLC6517d564-ea55-4084-a8ab-34fea548c24e2021-11-05Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215563
application number: ANDA215563
ndc (product): 70954-456

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
854901bisoprolol fumarate 10 MG Oral TabletPSNdf37d337-9978-0c31-e053-2a95a90a32582
854905bisoprolol fumarate 5 MG Oral TabletPSNdf37d337-9978-0c31-e053-2a95a90a32582
854901bisoprolol fumarate 10 MG Oral TabletSCDdf37d337-9978-0c31-e053-2a95a90a32582
854905bisoprolol fumarate 5 MG Oral TabletSCDdf37d337-9978-0c31-e053-2a95a90a32582
854901bisoprolol fumarate 10 MG Oral TabletPSN6517d564-ea55-4084-a8ab-34fea548c24e1
854905bisoprolol fumarate 5 MG Oral TabletPSN6517d564-ea55-4084-a8ab-34fea548c24e1
854901bisoprolol fumarate 10 MG Oral TabletSCD6517d564-ea55-4084-a8ab-34fea548c24e1
854905bisoprolol fumarate 5 MG Oral TabletSCD6517d564-ea55-4084-a8ab-34fea548c24e1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
70954-456-107095404561030 TABLET in 1 BOTTLE (70954-456-10) 30 tablet2021-10-290000-00-00NoNoCurrent
70954-456-2070954045620100 TABLET in 1 BOTTLE (70954-456-20) 100 tablet2021-10-290000-00-00NoNoCurrent