Methylene Blue

Product NDC
71288-811
11-digit product format
712880811
Labeler code
71288
Product ID
71288-811_65ff33db-d8c2-4591-8988-78e08b2298b6
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Methylene Blue
Dosage form
INJECTION
Route
INTRAVENOUS
Labeler
Meitheal Pharmaceuticals Inc.
Application
ANDA217380
Marketing category
ANDA
Marketing start
2025-01-23
Substance
METHYLENE BLUE
Active strength
5 mg/mL
Pharmacologic classes
Oxidation-Reduction Activity [MoA], Oxidation-Reduction Agent [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217380-001METHYLENE BLUEMETHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2025-01-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A217380-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A217380-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2025-01-23caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A217380-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2025-01-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217380-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2025-01-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08A217380-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2025-01-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217380-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2025-01-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217380-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2025-01-23b8a1b40f171c…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217380-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2025-01-23a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A217380-001AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A217380-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217380-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217380-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217380-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217380-001AP1b8a1b40f171c…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217380-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Methylene Blue
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METHYLENE BLUE5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
T42P99266KInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1788984Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2566ce72-9d19-42e5-80f9-8fc4612b1effAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c39b72c3-7732-4ed2-a995-e6aa3a665a54Product name320250819

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71288-811-10Methylene Blue10 mL in 1 VIAL, SINGLE-DOSEINJECTION108
71288-811-11Methylene Blue5 in 1 CARTONINJECTION58

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
71288-811-10ML - Milliliter71288-811b53c63e7-5947-4714-9bc0-46f0d7f999e112025-02-10
71288-811-11ML - Milliliter71288-811499feb7b-a9bb-42e3-8f4c-a838a3d29cad12025-02-10

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71288-811METHYLENE BLUE INJECTION [MEITHEAL PHARMACEUTICALS INC.]8Current NDC, 2 package rows20250205_2566ce72-9d19-42e5-80f9-8fc4612b1eff.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Methylene BlueMETHYLENE BLUEMeitheal Pharmaceuticals Inc.2566ce72-9d19-42e5-80f9-8fc4612b1eff2025-01-27Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217380
application number: ANDA217380
ndc (product): 71288-811

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1788984methylene blue 50 MG in 10 ML InjectionPSN2566ce72-9d19-42e5-80f9-8fc4612b1eff8
178898410 ML methylene blue 5 MG/ML InjectionSCD2566ce72-9d19-42e5-80f9-8fc4612b1eff8
1788984methylene blue 50 MG per 10 ML InjectionSY2566ce72-9d19-42e5-80f9-8fc4612b1eff8

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
71288-811-107128808111010 mL in 1 VIAL, SINGLE-DOSE10 mlHistorical
71288-811-11712880811115 VIAL, SINGLE-DOSE in 1 CARTON (71288-811-11) / 10 mL in 1 VIAL, SINGLE-DOSE (71288-811-10) 2025-01-23NoNoCurrent