METHADONE HYDROCHLORIDE

Product NDC
71335-1360
11-digit product format
713351360
Labeler code
71335
Product ID
71335-1360_6f29db41-72f8-4eee-b826-d095449170f8
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
METHADONE HYDROCHLORIDE
Dosage form
TABLET
Route
ORAL
Labeler
Bryant Ranch Prepack
Application
ANDA090635
Marketing category
ANDA
Marketing start
2012-01-16
Substance
METHADONE HYDROCHLORIDE
Active strength
10 mg/1
Pharmacologic classes
Full Opioid Agonists [MoA], Opioid Agonist [EPC]
DEA schedule
CII
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A090635-001METHADONE HYDROCHLORIDEMETHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25
A090635-002METHADONE HYDROCHLORIDEMETHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-22

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A090635-001AA
A090635-002AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 80 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25caaa826d4ba7…
2026-08-18 06:07:402026-07A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-22caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-255bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25d06236e962d9…
2024-10-29 15:01 UTC2024-10A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-2579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-251e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-258072bd15b7f6…
2024-05-31 18:47 UTC2024-05A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-228072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-255c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-225c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-255d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-225d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-254b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-224b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A090635-002METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2020-09-22bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A090635-001METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2009-11-25782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 80 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A090635-001AA1caaa826d4ba7…
2026-08-18 06:07:402026-07A090635-002AA1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A090635-001AA1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090635-002AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090635-001AA131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090635-002AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A090635-001AA16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090635-002AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090635-001AA1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090635-002AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090635-001AA1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090635-002AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090635-001AA103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090635-002AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090635-001AA12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090635-002AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090635-001AA15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090635-002AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090635-001AA1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090635-002AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090635-001AA1d06236e962d9…
2024-10-29 15:01 UTC2024-10A090635-002AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090635-001AA179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090635-002AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090635-001AA1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090635-002AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090635-001AA11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090635-002AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090635-001AA18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A090635-002AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090635-001AA15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090635-002AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090635-001AA15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A090635-002AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090635-001AA14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A090635-002AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090635-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090635-001AA1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A090635-002AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A090635-001AA1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
METHADONE HYDROCHLORIDE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METHADONE HYDROCHLORIDE10 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
229809935BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
864706Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7a8635fe-6183-4cda-9029-50e4e6dd5832Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
bc6c52c8-e3e2-9042-21d0-6770dcf1a49bProduct name320250819
a48f0261-b6cc-12b3-49fd-ed131bc5aa96Product name420210902
00dcb24c-d95e-78f6-6c1b-4d7b709bb2b9Product name620200708
a6a96832-f31d-b458-45cb-abb8bd940b44Product name220200304

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71335-1360-0METHADONE HYDROCHLORIDE168 in 1 BOTTLETABLET1684
71335-1360-1METHADONE HYDROCHLORIDE15 in 1 BOTTLETABLET154
71335-1360-2METHADONE HYDROCHLORIDE30 in 1 BOTTLETABLET304
71335-1360-3METHADONE HYDROCHLORIDE90 in 1 BOTTLETABLET904
71335-1360-4METHADONE HYDROCHLORIDE120 in 1 BOTTLETABLET1204
71335-1360-5METHADONE HYDROCHLORIDE180 in 1 BOTTLETABLET1804
71335-1360-6METHADONE HYDROCHLORIDE60 in 1 BOTTLETABLET604
71335-1360-7METHADONE HYDROCHLORIDE28 in 1 BOTTLETABLET284
71335-1360-8METHADONE HYDROCHLORIDE112 in 1 BOTTLETABLET1124
71335-1360-9METHADONE HYDROCHLORIDE56 in 1 BOTTLETABLET564

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
71335-1360-3EA - Each71335-136079fed854-46f3-4fbf-81d3-5fa05d33620312022-07-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71335-1360METHADONE HYDROCHLORIDE TABLET [BRYANT RANCH PREPACK]4Current NDC, Legacy NDC, 10 package rows20231107_7a8635fe-6183-4cda-9029-50e4e6dd5832.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Methadone HydrochlorideMETHADONE HYDROCHLORIDEAscend Laboratories, LLCf0366917-f745-4b01-a662-a98a7d80b4a02026-04-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090635
application number: ANDA090635
METHADONE HYDROCHLORIDEMETHADONE HYDROCHLORIDEBryant Ranch Prepack7a8635fe-6183-4cda-9029-50e4e6dd58322023-11-06Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090635
application number: ANDA090635
ndc (product): 71335-1360

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
864706methadone HCl 10 MG Oral TabletPSN7a8635fe-6183-4cda-9029-50e4e6dd58324
864706methadone hydrochloride 10 MG Oral TabletSCD7a8635fe-6183-4cda-9029-50e4e6dd58324

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
71335-1360-071335136000168 TABLET in 1 BOTTLE (71335-1360-0) 168 tablet2022-09-280000-00-00NoNoCurrent
71335-1360-17133513600115 TABLET in 1 BOTTLE (71335-1360-1) 15 tablet2022-09-280000-00-00NoNoCurrent
71335-1360-27133513600230 TABLET in 1 BOTTLE (71335-1360-2) 30 tablet2019-10-010000-00-00NoNoCurrent
71335-1360-37133513600390 TABLET in 1 BOTTLE (71335-1360-3) 90 tablet2020-08-140000-00-00NoNoCurrent
71335-1360-471335136004120 TABLET in 1 BOTTLE (71335-1360-4) 120 tablet2022-09-280000-00-00NoNoCurrent
71335-1360-571335136005180 TABLET in 1 BOTTLE (71335-1360-5) 180 tablet2022-09-280000-00-00NoNoCurrent
71335-1360-67133513600660 TABLET in 1 BOTTLE (71335-1360-6) 60 tablet2022-09-280000-00-00NoNoCurrent
71335-1360-77133513600728 TABLET in 1 BOTTLE (71335-1360-7) 28 tablet2022-09-280000-00-00NoNoCurrent
71335-1360-871335136008112 TABLET in 1 BOTTLE (71335-1360-8) 112 tablet2022-09-280000-00-00NoNoCurrent
71335-1360-97133513600956 TABLET in 1 BOTTLE (71335-1360-9) 56 tablet2022-09-280000-00-00NoNoCurrent