Bisoprolol

Product NDC
71335-1678
11-digit product format
713351678
Labeler code
71335
Product ID
71335-1678_4bb725ef-4484-4f1a-a2b4-471633683660
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Bisoprolol fumarate
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Bryant Ranch Prepack
Application
ANDA075474
Marketing category
ANDA
Marketing start
2019-06-20
Substance
BISOPROLOL FUMARATE
Active strength
5 mg/1
Pharmacologic classes
Adrenergic beta-Antagonists [MoA], beta-Adrenergic Blocker [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A075474-001BISOPROLOL FUMARATEBISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-25
A075474-002BISOPROLOL FUMARATEBISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A075474-001AB
A075474-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-255bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-25d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-25d06236e962d9…
2024-10-29 15:01 UTC2024-10A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-2579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-25301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-251e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-258072bd15b7f6…
2024-05-31 18:47 UTC2024-05A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-255c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-255d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-254b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-2574a2ff9319b5…
2019-12-13 00:20 UTC2019-12A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-25bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A075474-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2002-10-25782e0a99824c…
2021-12-28 21:50 UTC2021-12A075474-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2002-10-25782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 80 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A075474-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A075474-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075474-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075474-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A075474-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A075474-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075474-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075474-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075474-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075474-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075474-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075474-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075474-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075474-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075474-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075474-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075474-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075474-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A075474-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A075474-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075474-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075474-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075474-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075474-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075474-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075474-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A075474-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A075474-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075474-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075474-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A075474-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A075474-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A075474-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A075474-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A075474-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A075474-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A075474-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A075474-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A075474-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A075474-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Bisoprolol
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BISOPROLOL FUMARATE5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
UR59KN573LInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
854905Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
91d114ce-5551-455e-82df-d058eb222ac1Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
97e4a60d-917d-ef62-dc8a-bd557b62b708Product name720260129
9b303cd4-3186-2454-5706-3137e8b2dfd2Product name420221110

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71335-1678-1Bisoprolol30 in 1 BOTTLETABLET, FILM COATED303
71335-1678-2Bisoprolol100 in 1 BOTTLETABLET, FILM COATED1003
71335-1678-3Bisoprolol90 in 1 BOTTLETABLET, FILM COATED903
71335-1678-4Bisoprolol28 in 1 BOTTLETABLET, FILM COATED283
71335-1678-5Bisoprolol120 in 1 BOTTLETABLET, FILM COATED1203

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71335-1678BISOPROLOL (BISOPROLOL FUMARATE) TABLET, FILM COATED [BRYANT RANCH PREPACK]3Current NDC, Legacy NDC, 5 package rows20231118_91d114ce-5551-455e-82df-d058eb222ac1.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
BisoprololBISOPROLOL FUMARATEBryant Ranch Prepack7ec24259-0f37-4389-873b-e62267a21d672024-05-23Warnings, Adverse reactionsExact identifier
application applno (ANDA): 075474
application number: ANDA075474
BisoprololBISOPROLOL FUMARATEBryant Ranch Prepack78056d0b-2265-4da3-a4fe-b96d982898482023-12-07Warnings, Adverse reactionsExact identifier
application applno (ANDA): 075474
application number: ANDA075474
BisoprololBISOPROLOL FUMARATEBryant Ranch Prepack91d114ce-5551-455e-82df-d058eb222ac12023-11-17Warnings, Adverse reactionsExact identifier
application applno (ANDA): 075474
application number: ANDA075474
ndc (product): 71335-1678
BisoprololBISOPROLOL FUMARATETruPharma, LLCbba0bc2b-602f-4df1-a761-85bd3c80c7de2021-01-14Warnings, Adverse reactionsExact identifier
application applno (ANDA): 075474
application number: ANDA075474

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
854905bisoprolol fumarate 5 MG Oral TabletPSN91d114ce-5551-455e-82df-d058eb222ac13
854905bisoprolol fumarate 5 MG Oral TabletSCD91d114ce-5551-455e-82df-d058eb222ac13

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
71335-1678-17133516780130 TABLET, FILM COATED in 1 BOTTLE (71335-1678-1) 2020-07-280000-00-00NoNoCurrent
71335-1678-271335167802100 TABLET, FILM COATED in 1 BOTTLE (71335-1678-2) 2021-12-290000-00-00NoNoCurrent
71335-1678-37133516780390 TABLET, FILM COATED in 1 BOTTLE (71335-1678-3) 2021-12-290000-00-00NoNoCurrent
71335-1678-47133516780428 TABLET, FILM COATED in 1 BOTTLE (71335-1678-4) 2021-12-290000-00-00NoNoCurrent
71335-1678-571335167805120 TABLET, FILM COATED in 1 BOTTLE (71335-1678-5) 2021-12-290000-00-00NoNoCurrent